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Title: Two Decades of Laccases: Advancing Sustainability in the Chemical Industry

Abstract

Given the current state of environmental affairs and that our future on this planet as we know it is in jeopardy, research and development into greener and more sustainable technologies within the chemical and forest products industries is at its peak. The need for environmentally benign practices is propelling new green processes, given the global scale of these industries. These challenges are also impacting academic research and our reagents of interest are laccases. Furthermore, these enzymes are employed in a variety of biotechnological applications due to their native function as catalytic oxidants. They are about as green as it gets when it comes to chemical processes, requiring O2 as their only co-substrate and producing H2O as the sole by-product. The following account will review our twenty year journey on the use of these enzymes within our research group, from their initial use in biobleaching of kraft pulps and for fiber modification within the pulp and paper industry, to their current application as green catalytic oxidants in the field of synthetic organic chemistry.

Authors:
 [1]; ORCiD logo [2]
  1. Georgia Inst. of Technology, Atlanta, GA (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
  2. Georgia Inst. of Technology, Atlanta, GA (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Univ. of Tennessee, Knoxville, TN (United States)
Publication Date:
Research Org.:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Biological and Environmental Research (BER)
OSTI Identifier:
1376597
Grant/Contract Number:  
AC05-00OR22725
Resource Type:
Accepted Manuscript
Journal Name:
Chemical Record
Additional Journal Information:
Journal Volume: 17; Journal Issue: 1; Journal ID: ISSN 1527-8999
Publisher:
Wiley
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; biotechnology; green chemistry; laccases; organic synthesis; sustainability

Citation Formats

Cannatelli, Mark D., and Ragauskas, Arthur J. Two Decades of Laccases: Advancing Sustainability in the Chemical Industry. United States: N. p., 2016. Web. doi:10.1002/tcr.201600033.
Cannatelli, Mark D., & Ragauskas, Arthur J. Two Decades of Laccases: Advancing Sustainability in the Chemical Industry. United States. https://doi.org/10.1002/tcr.201600033
Cannatelli, Mark D., and Ragauskas, Arthur J. Fri . "Two Decades of Laccases: Advancing Sustainability in the Chemical Industry". United States. https://doi.org/10.1002/tcr.201600033. https://www.osti.gov/servlets/purl/1376597.
@article{osti_1376597,
title = {Two Decades of Laccases: Advancing Sustainability in the Chemical Industry},
author = {Cannatelli, Mark D. and Ragauskas, Arthur J.},
abstractNote = {Given the current state of environmental affairs and that our future on this planet as we know it is in jeopardy, research and development into greener and more sustainable technologies within the chemical and forest products industries is at its peak. The need for environmentally benign practices is propelling new green processes, given the global scale of these industries. These challenges are also impacting academic research and our reagents of interest are laccases. Furthermore, these enzymes are employed in a variety of biotechnological applications due to their native function as catalytic oxidants. They are about as green as it gets when it comes to chemical processes, requiring O2 as their only co-substrate and producing H2O as the sole by-product. The following account will review our twenty year journey on the use of these enzymes within our research group, from their initial use in biobleaching of kraft pulps and for fiber modification within the pulp and paper industry, to their current application as green catalytic oxidants in the field of synthetic organic chemistry.},
doi = {10.1002/tcr.201600033},
journal = {Chemical Record},
number = 1,
volume = 17,
place = {United States},
year = {Fri Aug 05 00:00:00 EDT 2016},
month = {Fri Aug 05 00:00:00 EDT 2016}
}

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Potential of a Funalia trogii laccase enzyme as an anticancer agent
journal, March 2014


The Structure of Rigidoporus lignosus Laccase Containing a Full Complement of Copper Ions, Reveals an Asymmetrical Arrangement for the T3 Copper Pair
journal, October 2004

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Synergistic enzymatic and microbial lignin conversion
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Synthesis andin vitro evaluation of some novel benzofuran derivatives as potential anti-HIV-1, anticancer, and antimicrobial agents
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Spectroscopic Studies and Electronic Structure Description of the High Potential Type 1 Copper Site in Fungal Laccase:  Insight into the Effect of the Axial Ligand
journal, August 1999

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Oxidation of non-phenolic substrates: An expanded role for laccase in lignin biodegradation
journal, July 1990


Visible-Light-Driven Oxidation of Organic Substrates with Dioxygen Mediated by a [Ru(bpy) 3 ] 2+ /Laccase System
journal, August 2015

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Laccase-Mediator Biobleaching Applied to a Direct Yellow Dyed Paper
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Highly efficient synthesis of aldehydes by layer by layer multi-walled carbon nanotubes (MWCNTs) laccase mediator systems
journal, June 2015


Molecular docking and dynamics simulation analyses unraveling the differential enzymatic catalysis by plant and fungal laccases with respect to lignin biosynthesis and degradation
journal, November 2014

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First description of a laccase-like enzyme in soil algae
journal, July 2010

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One-pot synthesis of 1,4-naphthoquinones and related structures with laccase
journal, January 2007

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  • Green Chemistry, Vol. 9, Issue 5
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Characterization of polyphenol oxidase from Chaetomium thermophile, a thermophilic fungus.
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Nature of the Intermediate Formed in the Reduction of O 2 to H 2 O at the Trinuclear Copper Cluster Active Site in Native Laccase
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Shifting the optimal pH of activity for a laccase from the fungus Trametes versicolor by structure-based mutagenesis
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Works referencing / citing this record:

Synthesis of Azobenzene Dyes Mediated by CotA Laccase
journal, November 2018

  • Sousa, Ana Catarina; Baptista, Sara R.; Martins, Lígia O.
  • Chemistry - An Asian Journal, Vol. 14, Issue 1
  • DOI: 10.1002/asia.201801450

Sequential Two‐Step Stereoselective Amination of Allylic Alcohols through the Combination of Laccases and Amine Transaminases
journal, November 2019

  • Albarrán‐Velo, Jesús; Lavandera, Iván; Gotor‐Fernández, Vicente
  • ChemBioChem, Vol. 21, Issue 1-2
  • DOI: 10.1002/cbic.201900473

One‐Pot Catalytic Synthesis of Aniline‐Copolymer‐Containing Reactive Aldehyde Groups Using a Laccase‐Mediator System
journal, September 2019

  • Khlupova, Maria; Morozova, Olga; Shumakovich, Galina
  • ChemistrySelect, Vol. 4, Issue 35
  • DOI: 10.1002/slct.201902403

Gongronella sp. w5 elevates Coprinopsis cinerea laccase production by carbon source syntrophism and secondary metabolite induction
journal, November 2018

  • Hu, Jun; Zhang, Yinliang; Xu, Yong
  • Applied Microbiology and Biotechnology, Vol. 103, Issue 1
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A first report on competitive inhibition of laccase enzyme by lignin degradation intermediates
journal, December 2019


Decolorization and detoxification of textile wastewaters by recombinant Myceliophthora thermophila and Trametes trogii laccases
journal, November 2018


Soil and entomopathogenic fungi with potential for biodegradation of insecticides: degradation of flubendiamide in vivo by fungi and in vitro by laccase
journal, November 2019

  • Yada, George M.; Shiraishi, Igor S.; Dekker, Robert F. H.
  • Annals of Microbiology, Vol. 69, Issue 13
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Immobilized Cerrena sp. laccase: preparation, thermal inactivation, and operational stability in malachite green decolorization
journal, November 2017


Aryl C–H amination initiated by laccase-mediated oxidation of 4-phenylurazole
journal, January 2019

  • Chen, Yu-Jue; Zhang, Guo-Yan; He, Yan-Hong
  • Catalysis Science & Technology, Vol. 9, Issue 16
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Efficient and sustainable laccase-catalyzed iodination of p -substituted phenols using KI as iodine source and aerial O 2 as oxidant
journal, January 2019

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