Cooperation in microbial communities and their biotechnological applications
Abstract
Microbial communities are increasingly utilized in biotechnology. Efficiency and productivity in many of these applications depends on the presence of cooperative interactions between members of the community. Two key processes underlying these interactions are the production of public goods and metabolic cross-feeding, which can be understood in the general framework of ecological and evolutionary (eco-evo) dynamics. In this review, we illustrate the relevance of cooperative interactions in microbial biotechnological processes, discuss their mechanistic origins and analyse their evolutionary resilience. Cooperative behaviours can be damaged by the emergence of ‘cheating’ cells that benefit from the cooperative interactions but do not contribute to them. Despite this, cooperative interactions can be stabilized by spatial segregation, by the presence of feedbacks between the evolutionary dynamics and the ecology of the community, by the role of regulatory systems coupled to the environmental conditions and by the action of horizontal gene transfer. Cooperative interactions enrich microbial communities with a higher degree of robustness against environmental stress and can facilitate the evolution of more complex traits. Therefore, the evolutionary resilience of microbial communities and their ability to constraint detrimental mutants should be considered to design robust biotechnological applications.
- Authors:
-
- School of Informatics, BBSRC/EPSRC/MRC Synthetic Biology Research Centre, University of Edinburgh, Edinburgh EH8 9AB UK
- Center for Nonlinear Studies, Theoretical Division (T-6), Los Alamos National Laboratory, Los Alamos NM 87545 USA
- School of Life Sciences, BBSRC/EPSRC Warwick Integrative Synthetic Biology Centre, University of Warwick, Coventry CV4 7AL UK
- Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH UK
- Publication Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC)
- OSTI Identifier:
- 1359990
- Alternate Identifier(s):
- OSTI ID: 1359991; OSTI ID: 1625849
- Grant/Contract Number:
- XWJX00/3000FENG; AC52-06NA25396
- Resource Type:
- Published Article
- Journal Name:
- Environmental Microbiology
- Additional Journal Information:
- Journal Name: Environmental Microbiology; Journal ID: ISSN 1462-2912
- Publisher:
- Wiley
- Country of Publication:
- United Kingdom
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; Microbiology
Citation Formats
Cavaliere, Matteo, Feng, Song, Soyer, Orkun S., and Jiménez, José I. Cooperation in microbial communities and their biotechnological applications. United Kingdom: N. p., 2017.
Web. doi:10.1111/1462-2920.13767.
Cavaliere, Matteo, Feng, Song, Soyer, Orkun S., & Jiménez, José I. Cooperation in microbial communities and their biotechnological applications. United Kingdom. https://doi.org/10.1111/1462-2920.13767
Cavaliere, Matteo, Feng, Song, Soyer, Orkun S., and Jiménez, José I. Wed .
"Cooperation in microbial communities and their biotechnological applications". United Kingdom. https://doi.org/10.1111/1462-2920.13767.
@article{osti_1359990,
title = {Cooperation in microbial communities and their biotechnological applications},
author = {Cavaliere, Matteo and Feng, Song and Soyer, Orkun S. and Jiménez, José I.},
abstractNote = {Microbial communities are increasingly utilized in biotechnology. Efficiency and productivity in many of these applications depends on the presence of cooperative interactions between members of the community. Two key processes underlying these interactions are the production of public goods and metabolic cross-feeding, which can be understood in the general framework of ecological and evolutionary (eco-evo) dynamics. In this review, we illustrate the relevance of cooperative interactions in microbial biotechnological processes, discuss their mechanistic origins and analyse their evolutionary resilience. Cooperative behaviours can be damaged by the emergence of ‘cheating’ cells that benefit from the cooperative interactions but do not contribute to them. Despite this, cooperative interactions can be stabilized by spatial segregation, by the presence of feedbacks between the evolutionary dynamics and the ecology of the community, by the role of regulatory systems coupled to the environmental conditions and by the action of horizontal gene transfer. Cooperative interactions enrich microbial communities with a higher degree of robustness against environmental stress and can facilitate the evolution of more complex traits. Therefore, the evolutionary resilience of microbial communities and their ability to constraint detrimental mutants should be considered to design robust biotechnological applications.},
doi = {10.1111/1462-2920.13767},
journal = {Environmental Microbiology},
number = ,
volume = ,
place = {United Kingdom},
year = {Wed Apr 26 00:00:00 EDT 2017},
month = {Wed Apr 26 00:00:00 EDT 2017}
}
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https://doi.org/10.1111/1462-2920.13767
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