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Title: Discovery of highly potent and selective Bruton’s tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability

Authors:
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Publication Date:
Type:
Publisher's Accepted Manuscript
Journal Name:
Bioorganic and Medicinal Chemistry Letters
Additional Journal Information:
Journal Volume: 26; Journal Issue: 2; Related Information: CHORUS Timestamp: 2018-09-17 08:58:17; Journal ID: ISSN 0960-894X
Publisher:
Elsevier
Sponsoring Org:
USDOE
Country of Publication:
United Kingdom
Language:
English
OSTI Identifier:
1358848

Young, Wendy B., Barbosa, James, Blomgren, Peter, Bremer, Meire C., Crawford, James J., Dambach, Donna, Eigenbrot, Charles, Gallion, Steve, Johnson, Adam R., Kropf, Jeffrey E., Lee, Seung H., Liu, Lichuan, Lubach, Joseph W., Macaluso, Jen, Maciejewski, Pat, Mitchell, Scott A., Ortwine, Daniel F., Di Paolo, Julie, Reif, Karin, Scheerens, Heleen, Schmitt, Aaron, Wang, Xiaojing, Wong, Harvey, Xiong, Jin-Ming, Xu, Jianjun, Yu, Christine, Zhao, Zhongdong, and Currie, Kevin S.. Discovery of highly potent and selective Bruton’s tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability. United Kingdom: N. p., Web. doi:10.1016/j.bmcl.2015.11.076.
Young, Wendy B., Barbosa, James, Blomgren, Peter, Bremer, Meire C., Crawford, James J., Dambach, Donna, Eigenbrot, Charles, Gallion, Steve, Johnson, Adam R., Kropf, Jeffrey E., Lee, Seung H., Liu, Lichuan, Lubach, Joseph W., Macaluso, Jen, Maciejewski, Pat, Mitchell, Scott A., Ortwine, Daniel F., Di Paolo, Julie, Reif, Karin, Scheerens, Heleen, Schmitt, Aaron, Wang, Xiaojing, Wong, Harvey, Xiong, Jin-Ming, Xu, Jianjun, Yu, Christine, Zhao, Zhongdong, & Currie, Kevin S.. Discovery of highly potent and selective Bruton’s tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability. United Kingdom. doi:10.1016/j.bmcl.2015.11.076.
Young, Wendy B., Barbosa, James, Blomgren, Peter, Bremer, Meire C., Crawford, James J., Dambach, Donna, Eigenbrot, Charles, Gallion, Steve, Johnson, Adam R., Kropf, Jeffrey E., Lee, Seung H., Liu, Lichuan, Lubach, Joseph W., Macaluso, Jen, Maciejewski, Pat, Mitchell, Scott A., Ortwine, Daniel F., Di Paolo, Julie, Reif, Karin, Scheerens, Heleen, Schmitt, Aaron, Wang, Xiaojing, Wong, Harvey, Xiong, Jin-Ming, Xu, Jianjun, Yu, Christine, Zhao, Zhongdong, and Currie, Kevin S.. 2016. "Discovery of highly potent and selective Bruton’s tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability". United Kingdom. doi:10.1016/j.bmcl.2015.11.076.
@article{osti_1358848,
title = {Discovery of highly potent and selective Bruton’s tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability},
author = {Young, Wendy B. and Barbosa, James and Blomgren, Peter and Bremer, Meire C. and Crawford, James J. and Dambach, Donna and Eigenbrot, Charles and Gallion, Steve and Johnson, Adam R. and Kropf, Jeffrey E. and Lee, Seung H. and Liu, Lichuan and Lubach, Joseph W. and Macaluso, Jen and Maciejewski, Pat and Mitchell, Scott A. and Ortwine, Daniel F. and Di Paolo, Julie and Reif, Karin and Scheerens, Heleen and Schmitt, Aaron and Wang, Xiaojing and Wong, Harvey and Xiong, Jin-Ming and Xu, Jianjun and Yu, Christine and Zhao, Zhongdong and Currie, Kevin S.},
abstractNote = {},
doi = {10.1016/j.bmcl.2015.11.076},
journal = {Bioorganic and Medicinal Chemistry Letters},
number = 2,
volume = 26,
place = {United Kingdom},
year = {2016},
month = {1}
}