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Title: Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia

Postmortem brain studies support dysregulated expression of the histone deacetylase enzymes, HDAC1 and HDAC2, as a central feature in diseases including schizophrenia, bipolar disorder, and depression.
Authors:
ORCiD logo [1] ;  [1] ;  [2] ;  [1] ;  [2] ;  [2] ;  [1] ;  [2]
  1. Brigham and Women's Hospital (Harvard Medical School), Boston, MA (United States). Massachusetts General Hospital
  2. National Inst. of Health (NIH), Bethesda, MD (United States)
Publication Date:
Grant/Contract Number:
SC0008430
Type:
Published Article
Journal Name:
ACS Chemical Neuroscience
Additional Journal Information:
Journal Volume: 8; Journal Issue: 3; Journal ID: ISSN 1948-7193
Publisher:
American Chemical Society (ACS)
Research Org:
Brigham and Women's Hospital (Harvard Medical School), Boston, MA (United States). Massachusetts General Hospital
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES
OSTI Identifier:
1357307
Alternate Identifier(s):
OSTI ID: 1426181