Risk of death among children of atomic bomb survivors after 62 years of follow-up: a cohort study

Grant, Eric J.; Furukawa, Kyoji; Sakata, Ritsu; Sugiyama, Hiromi; Sadakane, Atsuko; Takahashi, Ikuno; Utada, Mai; Shimizu, Yukiko; Ozasa, Kotaro

doi:10.1016/S1470-2045(15)00209-0

Title: Risk of death among children of atomic bomb survivors after 62 years of follow-up: a cohort study

Authors:: Grant, Eric J.; Furukawa, Kyoji; Sakata, Ritsu; Sugiyama, Hiromi; Sadakane, Atsuko; Takahashi, Ikuno; Utada, Mai; Shimizu, Yukiko; Ozasa, Kotaro

Publication Date:: Thu Oct 01 00:00:00 EDT 2015

Sponsoring Org.:: USDOE

OSTI Identifier:: 1357304

Grant/Contract Number:: HS0000031

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: Lancet Oncology

Additional Journal Information:: Journal Name: Lancet Oncology Journal Volume: 16 Journal Issue: 13; Journal ID: ISSN 1470-2045

Publisher:: Elsevier

Country of Publication:: United Kingdom

Language:: English

Citation Formats


                    Grant, Eric J., Furukawa, Kyoji, Sakata, Ritsu, Sugiyama, Hiromi, Sadakane, Atsuko, Takahashi, Ikuno, Utada, Mai, Shimizu, Yukiko, and Ozasa, Kotaro. Risk of death among children of atomic bomb survivors after 62 years of follow-up: a cohort study.  United Kingdom: N. p., 2015. 
Web.  doi:10.1016/S1470-2045(15)00209-0.

Copy to clipboard


                    Grant, Eric J., Furukawa, Kyoji, Sakata, Ritsu, Sugiyama, Hiromi, Sadakane, Atsuko, Takahashi, Ikuno, Utada, Mai, Shimizu, Yukiko, & Ozasa, Kotaro. Risk of death among children of atomic bomb survivors after 62 years of follow-up: a cohort study.  United Kingdom.  https://doi.org/10.1016/S1470-2045(15)00209-0

Copy to clipboard


                    Grant, Eric J., Furukawa, Kyoji, Sakata, Ritsu, Sugiyama, Hiromi, Sadakane, Atsuko, Takahashi, Ikuno, Utada, Mai, Shimizu, Yukiko, and Ozasa, Kotaro. Thu .  
"Risk of death among children of atomic bomb survivors after 62 years of follow-up: a cohort study".  United Kingdom.  https://doi.org/10.1016/S1470-2045(15)00209-0.

Copy to clipboard


                    
@article{osti_1357304,

  title        = {Risk of death among children of atomic bomb survivors after 62 years of follow-up: a cohort study},

  author       = {Grant, Eric J. and Furukawa, Kyoji and Sakata, Ritsu and Sugiyama, Hiromi and Sadakane, Atsuko and Takahashi, Ikuno and Utada, Mai and Shimizu, Yukiko and Ozasa, Kotaro},

  abstractNote = {},

  doi          = {10.1016/S1470-2045(15)00209-0},

  journal      = {Lancet Oncology},

  number       = 13,

  volume       = 16,

  place        = {United Kingdom},

  year         = {Thu Oct 01 00:00:00 EDT 2015},

  month        = {Thu Oct 01 00:00:00 EDT 2015}

}

Copy to clipboard

Journal Article:

Free Publicly Available Full Text

Accepted Manuscript (Publisher)

Publisher's Version of Record
https://doi.org/10.1016/S1470-2045(15)00209-0

Other availability

Search WorldCat to find libraries that may hold this journal

Citation Metrics:

Cited by: 28 works

Citation information provided by
Web of Science

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Mortality among the Offspring(F1) of Atomic Bomb Survivors, 1946-85.
journal, January 1991

Yoshimoto, Yasuhiko; Schull, William J.; Kato, Hiroo
Journal of Radiation Research, Vol. 32, Issue 4
DOI: 10.1269/jrr.32.327

Mortality in the Children of Atomic bomb Survivors and Controls
journal, February 1974

Neel, James V.; Kato, Hiroo; Schull, William J.
Genetics, Vol. 76, Issue 2
DOI: 10.1093/genetics/76.2.311

Germline minisatellite mutations in survivors of childhood and young adult cancer treated with radiation
journal, November 2010

Tawn, E. Janet; Rees, Gwen S.; Leith, Cheryl
International Journal of Radiation Biology, Vol. 87, Issue 3
DOI: 10.3109/09553002.2011.530338

Solid Cancer Incidence in Atomic Bomb Survivors: 1958–1998
journal, July 2007

Preston, D. L.; Ron, E.; Tokuoka, S.
Radiation Research, Vol. 168, Issue 1
DOI: 10.1667/RR0763.1

Congenital Anomalies in the Children of Cancer Survivors: A Report From the Childhood Cancer Survivor Study
journal, January 2012

Signorello, Lisa B.; Mulvihill, John J.; Green, Daniel M.
Journal of Clinical Oncology, Vol. 30, Issue 3
DOI: 10.1200/JCO.2011.37.2938

Cancer incidence in children and young adults did not increase relative to parental exposure to atomic bombs
journal, October 2003

Izumi, S.; Koyama, K.; Soda, M.
British Journal of Cancer, Vol. 89, Issue 9
DOI: 10.1038/sj.bjc.6601322

Impact of Comparison Group on Cohort dose Response Regression: an Example Using risk Estimation in Atomic-Bomb Survivors
journal, January 2001

Cologne, John B.; Preston, Dale L.
Health Physics, Vol. 80, Issue 5
DOI: 10.1097/00004032-200105000-00010

Studies of the Mortality of A-Bomb Survivors: I. Plan of Study and Mortality in the Medical Subsample (Selection I), 1950-1958
journal, March 1962

Beebe, Gilbert W.; Ishida, Morihiro; Jablon, Seymour
Radiation Research, Vol. 16, Issue 3
DOI: 10.2307/3571157

Invited Commentary: Missing Doses in the Life Span Study of Japanese Atomic Bomb Survivors
journal, February 2013

Ozasa, K.; Grant, E. J.; Cullings, H. M.
American Journal of Epidemiology, Vol. 177, Issue 6
DOI: 10.1093/aje/kws474

Children of Chernobyl Cleanup Workers do not Show Elevated Rates of Mutations in Minisatellite Alleles
journal, January 2001

Livshits, L. A.; Malyarchuk, S. G.; Lukyanova, E. M.
Radiation Research, Vol. 155, Issue 1
DOI: 10.1667/0033-7587(2001)155[0074:COCCWD]2.0.CO;2

Allowing for Random Errors in Radiation Dose Estimates for the Atomic Bomb Survivor Data
journal, September 1990

Pierce, Donald A.; Stram, Daniel O.; Vaeth, Michael
Radiation Research, Vol. 123, Issue 3
DOI: 10.2307/3577733

Cancer Risk Among Children of Atomic Bomb Survivors: A Review of RERF Epidemiologic Studies
journal, August 1990

Yoshimoto, Yasuhiko
JAMA, Vol. 264, Issue 5
DOI: 10.1001/jama.1990.03450050054027

Radiation-induced transgenerational alterations in genome stability and DNA damage
journal, June 2006

Barber, R. C.; Hickenbotham, P.; Hatch, T.
Oncogene, Vol. 25, Issue 56
DOI: 10.1038/sj.onc.1209723

Evidence relevant to untargeted and transgenerational effects in the offspring of irradiated parents
journal, July 2013

Little, Mark P.; Goodhead, Dudley T.; Bridges, Bryn A.
Mutation Research/Reviews in Mutation Research, Vol. 753, Issue 1
DOI: 10.1016/j.mrrev.2013.04.001

No Evidence of Increased Mutation Rates at Microsatellite Loci in Offspring of A-Bomb Survivors
journal, February 2010

Kodaira, M.; Ryo, H.; Kamada, N.
Radiation Research, Vol. 173, Issue 2
DOI: 10.1667/RR1991.1

Studies of the Mortality of Atomic Bomb Survivors, Report 14, 1950–2003: An Overview of Cancer and Noncancer Diseases
journal, March 2012

Ozasa, Kotaro; Shimizu, Yukiko; Suyama, Akihiko
Radiation Research, Vol. 177, Issue 3
DOI: 10.1667/RR2629.1

Minisatellite germline mutation rate in the Techa River population
journal, December 2006

Dubrova, Yuri E.; Ploshchanskaya, Olga G.; Kozionova, Olga S.
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 602, Issue 1-2
DOI: 10.1016/j.mrfmmm.2006.08.001

Radiation-related mortality among offspring of atomic bomb survivors: A half-century of follow-up
journal, August 2003

Izumi, Shizue; Suyama, Akihiko; Koyama, Kojiro
International Journal of Cancer, Vol. 107, Issue 2
DOI: 10.1002/ijc.11400

Symposium Paper: Genetic studies at the Atomic Bomb Casualty Commission-Radiation Effects Research Foundation: 1946-1997
journal, May 1998

Neel, J. V.
Proceedings of the National Academy of Sciences, Vol. 95, Issue 10
DOI: 10.1073/pnas.95.10.5432

Radiation risk of individual multifactorial diseases in offspring of the atomic-bomb survivors: a clinical health study
journal, March 2013

Tatsukawa, Yoshimi; Cologne, John B.; Hsu, Wan-Ling
Journal of Radiological Protection, Vol. 33, Issue 2
DOI: 10.1088/0952-4746/33/2/281

Similar Records in DOE PAGES and OSTI.GOV collections:

A prospective follow-up study of the association of radiation exposure with fatal and non-fatal stroke among atomic bomb survivors in Hiroshima and Nagasaki (1980–2003)

Journal Article Takahashi, Ikuno ; Abbott, Robert D. ; Ohshita, Tomohiko ; ... - BMJ Open

Use of medical radiotherapy has increased markedly in recent decades. Whether the consequence includes an increased risk of cardiovascular disease remains to be determined. The purpose of this study was to examine the association between radiation exposure and the incidence of stroke among Japanese atomic bomb survivors. Radiation exposure from the atomic bombing was assessed in 9515 subjects (34.8% men) with 24-year follow-up from 1980. Subjects were free of prevalent stroke when follow-up began. Stroke events and the underlying cause of death were reviewed to confirm the first-ever stroke. Subtypes (ischaemic and haemorrhagic events) were categorised based on established criteriamore »« less
https://doi.org/10.1136/bmjopen-2011-000654

Full Text Available
Type 2 diabetes, obesity, and breast cancer risk among Japanese women of the atomic bomb survivor cohort

Journal Article Maskarinec, Gertraud ; Sadakane, Atsuko ; Sugiyama, Hiromi ; ... - Cancer Epidemiology

Not provided.
https://doi.org/10.1016/j.canep.2019.04.009
Effect of follow-up period on minimal-significant dose in the atomic-bomb survivor studies

Journal Article Cologne, John ; Preston, Dale L. ; Grant, Eric J. ; ... - Radiation and Environmental Biophysics

It was recently suggested that earlier reports on solid-cancer mortality and incidence in the Life Span Study of atomic-bomb survivors contain still-useful information about low-dose risk that should not be ignored, because longer follow-up may lead to attenuated estimates of low-dose risk due to longer time since exposure. Here it is demonstrated, through the use of all follow-up data and risk models stratified on period of follow-up (as opposed to sub-setting the data by follow-up period), that the appearance of risk attenuation over time may be the result of less-precise risk estimation—in particular, imprecise estimation of effect-modification parameters—in the earliermore »« less
Cited by 6
https://doi.org/10.1007/s00411-017-0720-7
The possible impact of passive smoke exposure on radiation-related risk estimates for lung cancer among women: the life span study of atomic bomb survivors

Journal Article Hu, Audrey E. ; French, Benjamin ; Sakata, Ritsu ; ... - International Journal of Radiation Biology

Not provided.
https://doi.org/10.1080/09553002.2021.1976863
Cancer risk among children of atomic bomb survivors. A review of RERF epidemiologic studies. Radiation Effects Research Foundation

Journal Article Yoshimoto, Y - JAMA, Journal of the American Medical Association; (USA)

This article summarizes recent epidemiologic studies of cancer risk among the children of atomic bomb survivors conducted at the Radiation Effects Research Foundation. These children include two groups: (1) the in utero-exposed children (ie, those born to mothers who had been pregnant at the time of the bombings of Hiroshima and Nagasaki) and (2) the F1 population, which was conceived after the atomic-bombings and born to parents of whom one or both were atomic bomb survivors. Although from 1950 to 1984 only 18 cancer cases were identified among the in utero sample, cancer risk did appear to significantly increase asmore »« less
https://doi.org/10.1001/jama.264.5.596

Similar Records

Title: Risk of death among children of atomic bomb survivors after 62 years of follow-up: a cohort study

Citation Formats

Mortality among the Offspring(F1) of Atomic Bomb Survivors, 1946-85. journal, January 1991

Mortality in the Children of Atomic bomb Survivors and Controls journal, February 1974

Germline minisatellite mutations in survivors of childhood and young adult cancer treated with radiation journal, November 2010

Solid Cancer Incidence in Atomic Bomb Survivors: 1958–1998 journal, July 2007

Congenital Anomalies in the Children of Cancer Survivors: A Report From the Childhood Cancer Survivor Study journal, January 2012

Cancer incidence in children and young adults did not increase relative to parental exposure to atomic bombs journal, October 2003

Impact of Comparison Group on Cohort dose Response Regression: an Example Using risk Estimation in Atomic-Bomb Survivors journal, January 2001

Studies of the Mortality of A-Bomb Survivors: I. Plan of Study and Mortality in the Medical Subsample (Selection I), 1950-1958 journal, March 1962

Invited Commentary: Missing Doses in the Life Span Study of Japanese Atomic Bomb Survivors journal, February 2013

Children of Chernobyl Cleanup Workers do not Show Elevated Rates of Mutations in Minisatellite Alleles journal, January 2001

Allowing for Random Errors in Radiation Dose Estimates for the Atomic Bomb Survivor Data journal, September 1990

Cancer Risk Among Children of Atomic Bomb Survivors: A Review of RERF Epidemiologic Studies journal, August 1990

Radiation-induced transgenerational alterations in genome stability and DNA damage journal, June 2006

Evidence relevant to untargeted and transgenerational effects in the offspring of irradiated parents journal, July 2013

No Evidence of Increased Mutation Rates at Microsatellite Loci in Offspring of A-Bomb Survivors journal, February 2010

Studies of the Mortality of Atomic Bomb Survivors, Report 14, 1950–2003: An Overview of Cancer and Noncancer Diseases journal, March 2012

Minisatellite germline mutation rate in the Techa River population journal, December 2006

Radiation-related mortality among offspring of atomic bomb survivors: A half-century of follow-up journal, August 2003

Symposium Paper: Genetic studies at the Atomic Bomb Casualty Commission-Radiation Effects Research Foundation: 1946-1997 journal, May 1998

Radiation risk of individual multifactorial diseases in offspring of the atomic-bomb survivors: a clinical health study journal, March 2013

Mortality among the Offspring(F1) of Atomic Bomb Survivors, 1946-85.
journal, January 1991

Mortality in the Children of Atomic bomb Survivors and Controls
journal, February 1974

Germline minisatellite mutations in survivors of childhood and young adult cancer treated with radiation
journal, November 2010

Solid Cancer Incidence in Atomic Bomb Survivors: 1958–1998
journal, July 2007

Congenital Anomalies in the Children of Cancer Survivors: A Report From the Childhood Cancer Survivor Study
journal, January 2012

Cancer incidence in children and young adults did not increase relative to parental exposure to atomic bombs
journal, October 2003

Impact of Comparison Group on Cohort dose Response Regression: an Example Using risk Estimation in Atomic-Bomb Survivors
journal, January 2001

Studies of the Mortality of A-Bomb Survivors: I. Plan of Study and Mortality in the Medical Subsample (Selection I), 1950-1958
journal, March 1962

Invited Commentary: Missing Doses in the Life Span Study of Japanese Atomic Bomb Survivors
journal, February 2013

Children of Chernobyl Cleanup Workers do not Show Elevated Rates of Mutations in Minisatellite Alleles
journal, January 2001

Allowing for Random Errors in Radiation Dose Estimates for the Atomic Bomb Survivor Data
journal, September 1990

Cancer Risk Among Children of Atomic Bomb Survivors: A Review of RERF Epidemiologic Studies
journal, August 1990

Radiation-induced transgenerational alterations in genome stability and DNA damage
journal, June 2006

Evidence relevant to untargeted and transgenerational effects in the offspring of irradiated parents
journal, July 2013

No Evidence of Increased Mutation Rates at Microsatellite Loci in Offspring of A-Bomb Survivors
journal, February 2010

Studies of the Mortality of Atomic Bomb Survivors, Report 14, 1950–2003: An Overview of Cancer and Noncancer Diseases
journal, March 2012

Minisatellite germline mutation rate in the Techa River population
journal, December 2006

Radiation-related mortality among offspring of atomic bomb survivors: A half-century of follow-up
journal, August 2003

Symposium Paper: Genetic studies at the Atomic Bomb Casualty Commission-Radiation Effects Research Foundation: 1946-1997
journal, May 1998

Radiation risk of individual multifactorial diseases in offspring of the atomic-bomb survivors: a clinical health study
journal, March 2013