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Title: A Rapid Method for Quantification OF 242Pu in Urine Using Extraction Chromatography and ICP-MS

Occupational exposure to plutonium is generally monitored through analysis of urine samples. Typically, plutonium is separated from the sample and other actinides, and the concentration is determined using alpha spectroscopy. Current methods for separations and analysis are lengthy and require long count times. A new method for monitoring occupational exposure levels of plutonium has been developed, which requires fewer steps and overall less time than the alpha spectroscopy method. In this method, the urine is acidified, and a 239Pu internal standard is added. The urine is digested in a microwave oven, and plutonium is separated using an Eichrom TRU Resin column. The plutonium is eluted, and the eluant is injected directly into the Inductively Coupled Plasma–Mass Spectrometer (ICP-MS). Compared to a direct “dilute and shoot” method, a 30-fold improvement in sensitivity is achieved. This method was validated by analyzing several batches of spiked samples. Based on these analyses, a combined standard uncertainty plot, which relates uncertainty to concentration, was produced. As a result, the MDA 95 was calculated to be 7.0 × 10 –7 μg L –1, and the Lc95 was calculated to be 3.5 × 10 –7 μg L –1 for this method.
Authors:
 [1] ;  [2] ;  [2] ;  [3]
  1. Univ. of Nevada, Las Vegas, NV (United States). Radiochemistry Program
  2. Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). Analytical Services and Instrumentation Division
  3. Colorado State Univ., Fort Collins, CO (United States). Dept. of Environmental and Radiological Health Sciences
Publication Date:
Report Number(s):
LLNL-JRNL-744298
Journal ID: ISSN 0017-9078
Grant/Contract Number:
NA0000979; AC52‐07NA27344
Type:
Accepted Manuscript
Journal Name:
Health Physics
Additional Journal Information:
Journal Volume: 112; Journal Issue: 3; Journal ID: ISSN 0017-9078
Publisher:
Health Physics Society
Research Org:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States). Nuclear Science and Security Consortium
Sponsoring Org:
USDOE National Nuclear Security Administration (NNSA), Office of Defense Programs (DP) (NA-10)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 61 RADIATION PROTECTION AND DOSIMETRY; bioassay; plasma; plutonium; radiation protection; Radiation protection and dosimetry
OSTI Identifier:
1355354
Alternate Identifier(s):
OSTI ID: 1465265