SuperPose: a simple server for sophisticated structural superposition
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July 2004 |
The Genomic and Cellular Foundations of Animal Origins
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November 2013 |
Strategies to overcome resistance to targeted protein kinase inhibitors
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December 2004 |
Single-molecule paleoenzymology probes the chemistry of resurrected enzymes
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April 2011 |
c-Src Binds to the Cancer Drug Imatinib with an Inactive Abl/c-Kit Conformation and a Distributed Thermodynamic Penalty
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March 2007 |
Ancestral Sequence Reconstruction in Primate Mitochondrial DNA: Compositional Bias and Effect on Functional Inference
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June 2004 |
Protein kinases: evolution of dynamic regulatory proteins
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February 2011 |
An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates
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December 1979 |
Chemical Paleogenetics. Molecular "Restoration Studies" of Extinct Forms of Life.
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January 1963 |
A conserved protonation-dependent switch controls drug binding in the Abl kinase
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December 2008 |
The Different Flexibility of c-Src and c-Abl Kinases Regulates the Accessibility of a Druggable Inactive Conformation
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January 2012 |
Equally Potent Inhibition of c-Src and Abl by Compounds that Recognize Inactive Kinase Conformations
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March 2009 |
MolProbity : all-atom structure validation for macromolecular crystallography
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December 2009 |
Assessing the Accuracy of Ancestral Protein Reconstruction Methods
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January 2006 |
Missense meanderings in sequence space: a biophysical view of protein evolution
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August 2005 |
Joint Bayesian Estimation of Alignment and Phylogeny
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June 2005 |
Features and development of Coot
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March 2010 |
Thermofluor-based high-throughput stability optimization of proteins for structural studies
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October 2006 |
Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor PHA-739358
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September 2007 |
Inferring the palaeoenvironment of ancient bacteria on the basis of resurrected proteins
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September 2003 |
REFMAC 5 dictionary: organization of prior chemical knowledge and guidelines for its use
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November 2004 |
Mechanistic approaches to the study of evolution: the functional synthesis
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September 2007 |
Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase
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March 2003 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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journal
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January 2010 |
The Crystal Structure of a c-Src Complex in an Active Conformation Suggests Possible Steps in c-Src Activation
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June 2005 |
Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification
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June 2001 |
Analyzing protein structure and function using ancestral gene reconstruction
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journal
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June 2010 |
A Src-Like Inactive Conformation in the Abl Tyrosine Kinase Domain
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May 2006 |
The Evolution of Protein Kinase Inhibitors from Antagonists to Agonists of Cellular Signaling
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July 2011 |
Structural Basis of Src Tyrosine Kinase Inhibition with a New Class of Potent and Selective Trisubstituted Purine-based Compounds
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January 2006 |
Tyrosine phosphorylation: thirty years and counting
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journal
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April 2009 |
Defining the conserved internal architecture of a protein kinase
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March 2010 |
Explaining why Gleevec is a specific and potent inhibitor of Abl kinase
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January 2013 |
Conservation of Protein Structure over Four Billion Years
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September 2013 |
Energetic dissection of Gleevec's selectivity toward human tyrosine kinases
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September 2014 |
Scaling and assessment of data quality
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December 2005 |
Evolutionary biochemistry: revealing the historical and physical causes of protein properties
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July 2013 |
MOLREP an Automated Program for Molecular Replacement
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December 1997 |
Evolution of protein kinase signaling from yeast to man
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October 2002 |
PAML 4: Phylogenetic Analysis by Maximum Likelihood
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April 2007 |
XDS
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journal
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January 2010 |
Molecular Dynamics Simulations Show That Conformational Selection Governs the Binding Preferences of Imatinib for Several Tyrosine Kinases
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March 2010 |
High yield bacterial expression of active c-Abl and c-Src tyrosine kinases
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December 2005 |
Palaeotemperature trend for Precambrian life inferred from resurrected proteins
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February 2008 |
Retracing Evolution of Red Fluorescence in GFP-Like Proteins from Faviina Corals
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September 2009 |