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Title: Genomics and functional genomics in Chlamydomonas reinhardtii

The availability of the Chlamydomonas reinhardtii nuclear genome sequence continues to enable researchers to address biological questions relevant to algae, land plants and animals in unprecedented ways. As we continue to characterize and understand biological processes in C. reinhardtii and translate that knowledge to other systems, we are faced with the realization that many genes encode proteins without a defined function. The field of functional genomics aims to close this gap between genome sequence and protein function. Transcriptomes, proteomes and phenomes can each provide layers of gene-specific functional data while supplying a global snapshot of cellular behavior under different conditions. Herein we present a brief history of functional genomics, the present status of the C. reinhardtii genome, how genome-wide experiments can aid in supplying protein function inferences, and provide an outlook for functional genomics in C. reinhardtii.
Authors:
 [1] ;  [1]
  1. Brookhaven National Lab. (BNL), Upton, NY (United States). Dept. of Biology
Publication Date:
Report Number(s):
BNL-113704-2017-JA
Journal ID: ISSN 1862-5576
Grant/Contract Number:
SC0012704
Type:
Accepted Manuscript
Journal Name:
Microbiology Monographs
Additional Journal Information:
Journal Volume: 30; Journal ID: ISSN 1862-5576
Research Org:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Org:
USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES
OSTI Identifier:
1351725