Self-Assembly of an α-Helical Peptide into a Crystalline Two-Dimensional Nanoporous Framework
Abstract
Sequence-specific peptides have been demonstrated to self-assemble into structurally defined nano-scale ob-jects including nanofibers, nanotubes, and nanosheets. The latter structures display significant promise for the construction of hybrid materials for functional devices due to their extended planar geometry. Realization of this objective necessitates the ability to control the structural features of the resultant assemblies through the peptide sequence. The design of a amphiphilic peptide, 3FD-IL, is described that comprises two repeats of a canonical 18 amino acid sequence associated with straight xhelical structures. Peptide 3FD-IL displays three-fold screw symmetry in a helical conformation and self-assem-bles into nanosheets based on hexagonal packing of helices. Biophysical evidence from TEM, cryo-TEM, SAXS, AFM, and STEM measurements on the 3FD-IL nanosheets support a structural model based on a honeycomb lattice, in which the length of the peptide determines the thickness of the nanosheet and the packing of helices defines the presence of nanoscale channels that permeate the sheet. The honeycomb structure can be rationalized on the basis of geometrical packing frus-tration in which the channels occupy defect sites that define a periodic super-lattice. The resultant 2D materials may have potential as materials for nanoscale transport and controlled release applications.
- Authors:
-
- Emory Univ., Atlanta, GA (United States). Dept. of Chemistry
- Emory Univ., Atlanta, GA (United States). School of Medicine, Dept. of Pediatrics
- Brookhaven National Lab. (BNL), Upton, NY (United States)
- Argonne National Lab. (ANL), Argonne, IL (United States). X-ray Science Division
- Publication Date:
- Research Org.:
- Brookhaven National Lab. (BNL), Upton, NY (United States); Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Biological and Environmental Research (BER); National Institutes of Health (NIH); USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1351722
- Alternate Identifier(s):
- OSTI ID: 1373400
- Report Number(s):
- BNL-113693-2017-JA
Journal ID: ISSN 0002-7863
- Grant/Contract Number:
- SC0012704; W-31-109-Eng-38; S10RR025679; R01GM104540; UL1TR000454; CHE-1309817; CHE-1012620; CHE-1412580; AC02-06CH11357
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Journal of the American Chemical Society
- Additional Journal Information:
- Journal Volume: 138; Journal Issue: 50; Journal ID: ISSN 0002-7863
- Publisher:
- American Chemical Society (ACS)
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; Peptide design; self-assembly; nanosheet; porus material; honeycomb structure; porous material
Citation Formats
Magnotti, Elizabeth L., Hughes, Spencer A., Dillard, Rebecca S., Wang, Shengyuan, Hough, Lillian, Karumbamkandathil, Arshad, Lian, Tianquan, Wall, Joseph S., Zuo, Xiaobing, Wright, Elizabeth R., and Conticello, Vincent P. Self-Assembly of an α-Helical Peptide into a Crystalline Two-Dimensional Nanoporous Framework. United States: N. p., 2016.
Web. doi:10.1021/jacs.6b06592.
Magnotti, Elizabeth L., Hughes, Spencer A., Dillard, Rebecca S., Wang, Shengyuan, Hough, Lillian, Karumbamkandathil, Arshad, Lian, Tianquan, Wall, Joseph S., Zuo, Xiaobing, Wright, Elizabeth R., & Conticello, Vincent P. Self-Assembly of an α-Helical Peptide into a Crystalline Two-Dimensional Nanoporous Framework. United States. https://doi.org/10.1021/jacs.6b06592
Magnotti, Elizabeth L., Hughes, Spencer A., Dillard, Rebecca S., Wang, Shengyuan, Hough, Lillian, Karumbamkandathil, Arshad, Lian, Tianquan, Wall, Joseph S., Zuo, Xiaobing, Wright, Elizabeth R., and Conticello, Vincent P. Tue .
"Self-Assembly of an α-Helical Peptide into a Crystalline Two-Dimensional Nanoporous Framework". United States. https://doi.org/10.1021/jacs.6b06592. https://www.osti.gov/servlets/purl/1351722.
@article{osti_1351722,
title = {Self-Assembly of an α-Helical Peptide into a Crystalline Two-Dimensional Nanoporous Framework},
author = {Magnotti, Elizabeth L. and Hughes, Spencer A. and Dillard, Rebecca S. and Wang, Shengyuan and Hough, Lillian and Karumbamkandathil, Arshad and Lian, Tianquan and Wall, Joseph S. and Zuo, Xiaobing and Wright, Elizabeth R. and Conticello, Vincent P.},
abstractNote = {Sequence-specific peptides have been demonstrated to self-assemble into structurally defined nano-scale ob-jects including nanofibers, nanotubes, and nanosheets. The latter structures display significant promise for the construction of hybrid materials for functional devices due to their extended planar geometry. Realization of this objective necessitates the ability to control the structural features of the resultant assemblies through the peptide sequence. The design of a amphiphilic peptide, 3FD-IL, is described that comprises two repeats of a canonical 18 amino acid sequence associated with straight xhelical structures. Peptide 3FD-IL displays three-fold screw symmetry in a helical conformation and self-assem-bles into nanosheets based on hexagonal packing of helices. Biophysical evidence from TEM, cryo-TEM, SAXS, AFM, and STEM measurements on the 3FD-IL nanosheets support a structural model based on a honeycomb lattice, in which the length of the peptide determines the thickness of the nanosheet and the packing of helices defines the presence of nanoscale channels that permeate the sheet. The honeycomb structure can be rationalized on the basis of geometrical packing frus-tration in which the channels occupy defect sites that define a periodic super-lattice. The resultant 2D materials may have potential as materials for nanoscale transport and controlled release applications.},
doi = {10.1021/jacs.6b06592},
journal = {Journal of the American Chemical Society},
number = 50,
volume = 138,
place = {United States},
year = {2016},
month = {11}
}
Web of Science
Works referenced in this record:
Nanoarchitectonics for Dynamic Functional Materials from Atomic-/Molecular-Level Manipulation to Macroscopic Action
journal, October 2015
- Ariga, Katsuhiko; Li, Junbai; Fei, Jinbo
- Advanced Materials, Vol. 28, Issue 6
Two-dimensional nanoarchitectonics: organic and hybrid materials
journal, January 2012
- Govindaraju, T.; Avinash, M. B.
- Nanoscale, Vol. 4, Issue 20
Structurally Defined Nanoscale Sheets from Self-Assembly of Collagen-Mimetic Peptides
journal, March 2014
- Jiang, Tao; Xu, Chunfu; Liu, Yang
- Journal of the American Chemical Society, Vol. 136, Issue 11
Structurally Homogeneous Nanosheets from Self-Assembly of a Collagen-Mimetic Peptide
journal, June 2014
- Jiang, Tao; Xu, Chunfu; Zuo, Xiaobing
- Angewandte Chemie International Edition, Vol. 53, Issue 32
Rational Design of Multilayer Collagen Nanosheets with Compositional and Structural Control
journal, June 2015
- Jiang, Tao; Vail, Owen A.; Jiang, Zhigang
- Journal of the American Chemical Society, Vol. 137, Issue 24
Self-Assembly of Left- and Right-Handed Molecular Screws
journal, December 2013
- Xu, Fei; Khan, I. John; McGuinness, Kenneth
- Journal of the American Chemical Society, Vol. 135, Issue 50
Dissecting Electrostatic Contributions to Folding and Self-Assembly Using Designed Multicomponent Peptide Systems
journal, March 2016
- Parmar, Avanish S.; James, Jose K.; Grisham, Daniel R.
- Journal of the American Chemical Society, Vol. 138, Issue 13
Free-floating ultrathin two-dimensional crystals from sequence-specific peptoid polymers
journal, April 2010
- Nam, Ki Tae; Shelby, Sarah A.; Choi, Philip H.
- Nature Materials, Vol. 9, Issue 5
Shaken, Not Stirred: Collapsing a Peptoid Monolayer To Produce Free-Floating, Stable Nanosheets
journal, December 2011
- Sanii, Babak; Kudirka, Romas; Cho, Andrew
- Journal of the American Chemical Society, Vol. 133, Issue 51
Folding of a single-chain, information-rich polypeptoid sequence into a highly ordered nanosheet
journal, January 2011
- Kudirka, Romas; Tran, Helen; Sanii, Babak
- Biopolymers, Vol. 96, Issue 5
Assembly and molecular order of two-dimensional peptoid nanosheets through the oil–water interface
journal, September 2014
- Robertson, Ellen J.; Olivier, Gloria K.; Qian, Menglu
- Proceedings of the National Academy of Sciences, Vol. 111, Issue 37
Self-assembled arginine-coated peptide nanosheets in water
journal, January 2013
- Hamley, Ian W.; Dehsorkhi, Ashkan; Castelletto, Valeria
- Chemical Communications, Vol. 49, Issue 18
Tunable assembly of amyloid-forming peptides into nanosheets as a retrovirus carrier
journal, February 2015
- Dai, Bin; Li, Dan; Xi, Wenhui
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 10
Self-assembly of coherently dynamic, auxetic, two-dimensional protein crystals
journal, May 2016
- Suzuki, Yuta; Cardone, Giovanni; Restrepo, David
- Nature, Vol. 533, Issue 7603
Metal-directed, chemically tunable assembly of one-, two- and three-dimensional crystalline protein arrays
journal, March 2012
- Brodin, Jeffrey D.; Ambroggio, X. I.; Tang, Chunyan
- Nature Chemistry, Vol. 4, Issue 5
Exceptionally stable, redox-active supramolecular protein assemblies with emergent properties
journal, February 2014
- Brodin, J. D.; Carr, J. R.; Sontz, P. A.
- Proceedings of the National Academy of Sciences, Vol. 111, Issue 8
Helix to helix packing in proteins
journal, January 1981
- Chothia, Cyrus; Levitt, Michael; Richardson, Douglas
- Journal of Molecular Biology, Vol. 145, Issue 1
Helix packing angle preferences
journal, November 1997
- Bowie, James U.
- Nature Structural & Molecular Biology, Vol. 4, Issue 11
Helix-helix packing angle preferences for finite helix axes
journal, December 1998
- Walther, Dirk; Springer, Clayton; Cohen, Fred E.
- Proteins: Structure, Function, and Genetics, Vol. 33, Issue 4
Folding, aggregation and molecular recognition in peptides
journal, August 1992
- Karle, I. L.
- Acta Crystallographica Section B Structural Science, Vol. 48, Issue 4
Nucleation, Growth, and Form in Crystals of Peptide Helices
journal, January 2008
- Vasudev, Prema G.; Shamala, Narayanaswamy; Balaram, Padmanabhan
- The Journal of Physical Chemistry B, Vol. 112, Issue 4
Packed protein bilayers in the 0.90 å resolution structure of a designed alpha helical bundle
journal, January 1999
- Privé, Gilbert G.; Anderson, Daniel H.; Wesson, Laura
- Protein Science, Vol. 8, Issue 7
Centrosymmetric bilayers in the 0.75 å resolution structure of a designed alpha-helical peptide, D, L-Alpha-1
journal, January 1999
- Patterson, William R.; Anderson, Daniel H.; Degrado, William F.
- Protein Science, Vol. 8, Issue 7
A novel, multilayer structure of a helical peptide
journal, March 1996
- Taylor, K. S.; Lou, M. -Z.; Chin, T. -M.
- Protein Science, Vol. 5, Issue 3
Smectic ordering in solutions and films of a rod-like polymer owing to monodispersity of chain length
journal, September 1997
- Yu, Seungju M.; Conticello, Vincent P.; Zhang, Guanghui
- Nature, Vol. 389, Issue 6647
Nanometer-Scale Smectic Ordering of Genetically Engineered Rodlike Polymers: Synthesis and Characterization of Monodisperse Derivatives of Poly(γ-benzyl α, l -glutamate)
journal, July 2000
- Yu, Seungju M.; Soto, Carissa M.; Tirrell, David A.
- Journal of the American Chemical Society, Vol. 122, Issue 28
The Structure of α-Helical Coiled Coils
book, January 2005
- Lupas, Andrei N.; Gruber, Markus
- Fibrous Proteins: Coiled-Coils, Collagen and Elastomers, p. 37-38
New currency for old rope: from coiled-coil assemblies to α-helical barrels
journal, August 2012
- Woolfson, Derek N.; Bartlett, Gail J.; Bruning, Marc
- Current Opinion in Structural Biology, Vol. 22, Issue 4
A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology
journal, May 2012
- Fletcher, Jordan M.; Boyle, Aimee L.; Bruning, Marc
- ACS Synthetic Biology, Vol. 1, Issue 6
A de novo peptide hexamer with a mutable channel
journal, October 2011
- Zaccai, Nathan R.; Chi, Bertie; Thomson, Andrew R.
- Nature Chemical Biology, Vol. 7, Issue 12
Computational design of water-soluble α-helical barrels
journal, October 2014
- Thomson, Andrew R.; Wood, Christopher W.; Burton, Antony J.
- Science, Vol. 346, Issue 6208
High thermodynamic stability of parametrically designed helical bundles
journal, October 2014
- Huang, Po-Ssu; Oberdorfer, Gustav; Xu, Chunfu
- Science, Vol. 346, Issue 6208
Computational design of a protein crystal
journal, April 2012
- Lanci, C. J.; MacDermaid, C. M.; Kang, S. -g.
- Proceedings of the National Academy of Sciences, Vol. 109, Issue 19
The crystal structure of the designed trimeric coiled coil coil-VaLd: Implications for engineering crystals and supramolecular assemblies
journal, January 1997
- Ogihara, Nancy L.; Weiss, Manfred S.; Eisenberg, David
- Protein Science, Vol. 6, Issue 1, p. 80-88
Engineering nanoscale order into a designed protein fiber
journal, June 2007
- Papapostolou, D.; Smith, A. M.; Atkins, E. D. T.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 26
Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design
journal, July 2012
- Sharp, T. H.; Bruning, M.; Mantell, J.
- Proceedings of the National Academy of Sciences, Vol. 109, Issue 33
Modular Design of Self-Assembling Peptide-Based Nanotubes
journal, August 2015
- Burgess, Natasha C.; Sharp, Thomas H.; Thomas, Franziska
- Journal of the American Chemical Society, Vol. 137, Issue 33
Computationally designed peptides for self-assembly of nanostructured lattices
journal, September 2016
- Zhang, Huixi Violet; Polzer, Frank; Haider, Michael J.
- Science Advances, Vol. 2, Issue 9
The structure of proteins: Two hydrogen-bonded helical configurations of the polypeptide chain
journal, April 1951
- Pauling, L.; Corey, R. B.; Branson, H. R.
- Proceedings of the National Academy of Sciences, Vol. 37, Issue 4, p. 205-211
The role of the α-helix dipole in protein function and structure
journal, January 1985
- Hol, Wim G. J.
- Progress in Biophysics and Molecular Biology, Vol. 45, Issue 3
A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants
journal, November 1993
- Harbury, P.; Zhang, T; Kim, P.
- Science, Vol. 262, Issue 5138, p. 1401-1407
Coiled coils: new structures and new functions
journal, October 1996
- Lupas, A.
- Trends in Biochemical Sciences, Vol. 21, Issue 10
ATP Synthase b Subunit Dimerization Domain: A Right-Handed Coiled Coil with Offset Helices
journal, December 2006
- Del Rizzo, Paul A.; Bi, Yumin; Dunn, Stanley D.
- Journal of Molecular Biology, Vol. 364, Issue 4
The “Second Stalk” of Escherichia coli ATP Synthase: Structure of the Isolated Dimerization Domain † , ‡
journal, May 2002
- Del Rizzo, Paul A.; Bi, Yumin; Dunn, Stanley D.
- Biochemistry, Vol. 41, Issue 21
Probing Designability via a Generalized Model of Helical Bundle Geometry
journal, January 2011
- Grigoryan, Gevorg; DeGrado, William F.
- Journal of Molecular Biology, Vol. 405, Issue 4
Repacking protein cores with backbone freedom: structure prediction for coiled coils.
journal, August 1995
- Harbury, P. B.; Tidor, B.; Kim, P. S.
- Proceedings of the National Academy of Sciences, Vol. 92, Issue 18
Frustration and Frustrated Crystal Structures of Polymers and Biopolymers
journal, February 2012
- Lotz, Bernard
- Macromolecules, Vol. 45, Issue 5
Thermotropic polypeptides. 2. Molecular packing and thermotropic behavior of poly(L-glutamates) with long n-alkyl side chains
journal, November 1985
- Watanabe, Junji; Ono, Hirobumi; Uematsu, Ichitaro
- Macromolecules, Vol. 18, Issue 11
Columnar liquid crystals in polypeptides. 1. A columnar hexagonal liquid crystal observed in poly(.gamma.-octadecyl L-glutamate)
journal, May 1991
- Watanabe, Junji; Takashina, Yoshimasa
- Macromolecules, Vol. 24, Issue 11
Crystal transition and structure of poly (γ-n-alkyl glutamate)s
journal, April 1991
- Sasaki, Shintaro
- Journal of Polymer Science Part B: Polymer Physics, Vol. 29, Issue 5
Crystal structure of poly(γ-methyl L-glutamate) at high temperature
journal, February 1985
- Sasaki, Shintaro; Uematsu, Ichitaro
- Journal of Polymer Science: Polymer Physics Edition, Vol. 23, Issue 2
Metal-organic framework nanosheets as building blocks for molecular sieving membranes
journal, December 2014
- Peng, Y.; Li, Y.; Ban, Y.
- Science, Vol. 346, Issue 6215
Bulk Synthesis of Exfoliated Two-Dimensional Polymers Using Hydrazone-Linked Covalent Organic Frameworks
journal, September 2013
- Bunck, David N.; Dichtel, William R.
- Journal of the American Chemical Society, Vol. 135, Issue 40
Toward a Single-Layer Two-Dimensional Honeycomb Supramolecular Organic Framework in Water
journal, October 2013
- Zhang, Kang-Da; Tian, Jia; Hanifi, David
- Journal of the American Chemical Society, Vol. 135, Issue 47
Free-Standing Monolayer Two-Dimensional Supramolecular Organic Framework with Good Internal Order
journal, November 2015
- Pfeffermann, Martin; Dong, Renhao; Graf, Robert
- Journal of the American Chemical Society, Vol. 137, Issue 45
Self-Exfoliated Guanidinium-Based Ionic Covalent Organic Nanosheets (iCONs)
journal, February 2016
- Mitra, Shouvik; Kandambeth, Sharath; Biswal, Bishnu P.
- Journal of the American Chemical Society, Vol. 138, Issue 8
π-Conjugated Nickel Bis(dithiolene) Complex Nanosheet
journal, February 2013
- Kambe, Tetsuya; Sakamoto, Ryota; Hoshiko, Ken
- Journal of the American Chemical Society, Vol. 135, Issue 7
Synthesis of Free-Standing, Monolayered Organometallic Sheets at the Air/Water Interface
journal, July 2011
- Bauer, Thomas; Zheng, Zhikun; Renn, Alois
- Angewandte Chemie International Edition, Vol. 50, Issue 34
Synthesis of Two-Dimensional Analogues of Copolymers by Site-to-Site Transmetalation of Organometallic Monolayer Sheets
journal, April 2014
- Zheng, Zhikun; Opilik, Lothar; Schiffmann, Florian
- Journal of the American Chemical Society, Vol. 136, Issue 16
A photofunctional bottom-up bis(dipyrrinato)zinc(II) complex nanosheet
journal, April 2015
- Sakamoto, Ryota; Hoshiko, Ken; Liu, Qian
- Nature Communications, Vol. 6, Issue 1
Supramolecular Thiophene Nanosheets
journal, March 2013
- Zheng, Yijun; Zhou, Haixin; Liu, Dian
- Angewandte Chemie International Edition, Vol. 52, Issue 18
Reversible Scrolling of Two-Dimensional Sheets from the Self-Assembly of Laterally Grafted Amphiphilic Rods
journal, May 2009
- Lee, Eunji; Kim, Jung-Keun; Lee, Myongsoo
- Angewandte Chemie International Edition, Vol. 48, Issue 20
Large-Area, Free-Standing, Two-Dimensional Supramolecular Polymer Single-Layer Sheets for Highly Efficient Electrocatalytic Hydrogen Evolution
journal, August 2015
- Dong, Renhao; Pfeffermann, Martin; Liang, Haiwei
- Angewandte Chemie International Edition, Vol. 54, Issue 41
Folding DNA to create nanoscale shapes and patterns
journal, March 2006
- Rothemund, Paul W. K.
- Nature, Vol. 440, Issue 7082, p. 297-302
Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments
journal, April 2013
- Gradišar, Helena; Božič, Sabina; Doles, Tibor
- Nature Chemical Biology, Vol. 9, Issue 6
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
journal, May 2012
- King, N. P.; Sheffler, W.; Sawaya, M. R.
- Science, Vol. 336, Issue 6085
Accurate design of co-assembling multi-component protein nanomaterials
journal, May 2014
- King, Neil P.; Bale, Jacob B.; Sheffler, William
- Nature, Vol. 510, Issue 7503
Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression: Designed Protein Tetrahedron
journal, August 2015
- Bale, Jacob B.; Park, Rachel U.; Liu, Yuxi
- Protein Science, Vol. 24, Issue 10
Self-Assembling Cages from Coiled-Coil Peptide Modules
journal, April 2013
- Fletcher, J. M.; Harniman, R. L.; Barnes, F. R. H.
- Science, Vol. 340, Issue 6132
Structure of a Chaperone-Usher Pilus Reveals the Molecular Basis of Rod Uncoiling
journal, January 2016
- Hospenthal, Manuela K.; Redzej, Adam; Dodson, Karen
- Cell, Vol. 164, Issue 1-2
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy
journal, October 2015
- Sborgi, Lorenzo; Ravotti, Francesco; Dandey, Venkata P.
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 43
Structure of the Type VI Secretion System Contractile Sheath
journal, February 2015
- Kudryashev, Mikhail; Wang, Ray Yu-Ruei; Brackmann, Maximilian
- Cell, Vol. 160, Issue 5
Structural Plasticity of Helical Nanotubes Based on Coiled-Coil Assemblies
journal, February 2015
- Egelman, E. H.; Xu, C.; DiMaio, F.
- Structure, Vol. 23, Issue 2
De novo protein structure determination from near-atomic-resolution cryo-EM maps
journal, February 2015
- Wang, Ray Yu-Ruei; Kudryashev, Mikhail; Li, Xueming
- Nature Methods, Vol. 12, Issue 4
3D reconstruction of two-dimensional crystals
journal, September 2015
- Stahlberg, Henning; Biyani, Nikhil; Engel, Andreas
- Archives of Biochemistry and Biophysics, Vol. 581
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journal, March 2019
- Zhang, Jianting; Zhou, Kun; Zhang, Yejun
- Advanced Materials, Vol. 31, Issue 23
Pillar[5]arene-Based Supramolecular Organic Framework with Multi-Guest Detection and Recyclable Separation Properties
journal, December 2017
- Lin, Qi; Fan, Yan-Qing; Mao, Peng-Peng
- Chemistry - A European Journal, Vol. 24, Issue 4
Comparing proteins and nucleic acids for next-generation biomolecular engineering
journal, July 2018
- Pugh, Genevieve C.; Burns, Jonathan R.; Howorka, Stefan
- Nature Reviews Chemistry, Vol. 2, Issue 7
Degradation of phthalic acid esters (PAEs) by an enzyme mimic and its application in the degradation of intracellular DEHP
journal, January 2019
- Li, Xia; Li, Jianpeng; Zhu, Junxiang
- Chemical Communications, Vol. 55, Issue 89
The art of two-dimensional soft nanomaterials
journal, June 2019
- Zheng, Caini; Zhu, Jinhui; Yang, Chongqing
- Science China Chemistry, Vol. 62, Issue 9
Designing phenylalanine-based hybrid biological materials: controlling morphology via molecular composition
journal, January 2018
- Mushnoori, Srinivas; Schmidt, Kassandra; Nanda, Vikas
- Organic & Biomolecular Chemistry, Vol. 16, Issue 14
A novel pillar[5]arene-based supramolecular organic framework gel to achieve an ultrasensitive response by introducing the competition of cation⋯π and π⋯π interactions
journal, January 2018
- Zhang, You-Ming; Li, Yong-Fu; Zhong, Kai-Peng
- Soft Matter, Vol. 14, Issue 18
2D Crystal Engineering of Nanosheets Assembled from Helical Peptide Building Blocks
journal, August 2019
- Merg, Andrea D.; Touponse, Gavin; van Genderen, Eric
- Angewandte Chemie, Vol. 131, Issue 38
The design and biomedical applications of self-assembled two-dimensional organic biomaterials
journal, January 2019
- Zhang, Xiaoyuan; Gong, Coucong; Akakuru, Ozioma Udochukwu
- Chemical Society Reviews, Vol. 48, Issue 23
2D Crystal Engineering of Nanosheets Assembled from Helical Peptide Building Blocks
journal, September 2019
- Merg, Andrea D.; Touponse, Gavin; van Genderen, Eric
- Angewandte Chemie International Edition, Vol. 58, Issue 38