skip to main content

DOE PAGESDOE PAGES

Title: Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters

Authors:
 [1] ;  [2] ;  [1] ;  [3] ;  [4] ;  [5] ;  [1] ;  [1]
  1. DILIsym Services Inc, Research Triangle Park North Carolina USA
  2. DILIsym Services Inc, Research Triangle Park North Carolina USA, University of North Carolina Institute for Drug Safety Sciences, The Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill North Carolina USA
  3. ADME Transporters, Drug Safety and Metabolism, Innovative Medicines and Early Development, AstraZeneca, Cambridge United Kingdom
  4. Drug Safety and Metabolism, AstraZeneca R&D, Waltham Massachusetts USA
  5. University of North Carolina Institute for Drug Safety Sciences, The Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill North Carolina USA
Publication Date:
Type:
Published Article
Journal Name:
Clinical Pharmacology and Therapeutics
Additional Journal Information:
Journal Name: Clinical Pharmacology and Therapeutics Journal Volume: 101 Journal Issue: 4; Journal ID: ISSN 0009-9236
Publisher:
Wiley Blackwell (John Wiley & Sons)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
OSTI Identifier:
1344128
Alternate Identifier(s):
OSTI ID: 1344129

Yang, K., Battista, C., Woodhead, JL, Stahl, SH, Mettetal, JT, Watkins, PB, Siler, SQ, and Howell, BA. Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters. United States: N. p., Web. doi:10.1002/cpt.619.
Yang, K., Battista, C., Woodhead, JL, Stahl, SH, Mettetal, JT, Watkins, PB, Siler, SQ, & Howell, BA. Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters. United States. doi:10.1002/cpt.619.
Yang, K., Battista, C., Woodhead, JL, Stahl, SH, Mettetal, JT, Watkins, PB, Siler, SQ, and Howell, BA. 2017. "Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters". United States. doi:10.1002/cpt.619.
@article{osti_1344128,
title = {Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters},
author = {Yang, K. and Battista, C. and Woodhead, JL and Stahl, SH and Mettetal, JT and Watkins, PB and Siler, SQ and Howell, BA},
abstractNote = {},
doi = {10.1002/cpt.619},
journal = {Clinical Pharmacology and Therapeutics},
number = 4,
volume = 101,
place = {United States},
year = {2017},
month = {2}
}