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Title: The Chlorella vulgaris S-Nitrosoproteome under Nitrogen-Replete and -Deplete Conditions

Oleaginous microalgae synthesize and accumulate large quantities of lipids that are promising feedstocks for the production of biofuels (Hu et al., 2008; Williams and Laurens, 2010; Day et al., 2012; Quinn and Davis, 2015). The algal species Chlorella vulgaris accumulates triacylglycerides that dominate its cellular composition (>60% lipid based on dry cell weight) when cultured in medium lacking a nitrogen source (Guarnieri et al., 2011; Ikaran et al., 2015), which is a 'lipid trigger' in an array of microalgae. As such, C. vulgaris represents a model algal species for examination of lipid accumulation mechanisms and a potential deployment organism in industrial algal biofuels applications. C. vulgaris has been extensively characterized biochemically and physiologically (Converti et al., 2009; Liang et al., 2009), and de novo-generated transcriptomic and proteomic datasets have indicated that post-transcriptional and -translational mechanisms likely govern lipid accumulation in response to nitrogen starvation (Guarnieri et al., 2011, 2013). However, the specific mechanisms underlying lipid biosynthesis in response to nitrogen stress remain elusive.
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  1. National Renewable Energy Lab. (NREL), Golden, CO (United States)
Publication Date:
Report Number(s):
Journal ID: ISSN 2296-4185
Grant/Contract Number:
Accepted Manuscript
Journal Name:
Frontiers in Bioengineering and Biotechnology
Additional Journal Information:
Journal Volume: 4; Journal ID: ISSN 2296-4185
Frontiers Research Foundation
Research Org:
National Renewable Energy Lab. (NREL), Golden, CO (United States)
Sponsoring Org:
USDOE Office of Energy Efficiency and Renewable Energy (EERE), NREL Laboratory Directed Research and Development (LDRD)
Country of Publication:
United States
09 BIOMASS FUELS; Chlorella; biofuels; microalgae; S-nitrosylation; nitric oxide
OSTI Identifier: