skip to main content
DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Production of platinum radioisotopes at Brookhaven Linac Isotope Producer (BLIP)

Abstract

The accelerator production of platinum isotopes was investigated at the Brookhaven Linac Isotope Producer (BLIP). In this paper high purity natural platinum foils were irradiated at 53.2, 65.7, 105.2, 151.9, 162.9 and 173.3 MeV. The irradiated foils were digested in aqua regia and then converted to their hydrochloride salt with concentrated hydrochloric acid before analyzing by gamma spectrometry periodically for at least 10 days post end of bombardment. A wide range of platinum (Pt), gold (Au) and iridiu m (Ir) isotopes were identified. Effective cross sections at BLIP for Pt-188, Pt-189, Pt-191 and Pt-195m were compared to literature and theoretical cross sections determined using Empire-3.2. The majority of the effective cross sections (<70 MeV) confirm those reported in the literature. While the absolute values of the theoretical cross sections were up to a factor of 3 lower, Empire 3.2 modeled thresholds and maxima correlated well with experimental values. Preliminary evaluation into a rapid separation of Pt isotopes from high levels of Ir and Au isotopes proved to be a promising approach for large scale production. In conclusion, this study demonstrated that with the use of isotopically enriched target material accelerator production of selected platinum isotopes is feasible over a widemore » proton energy range.« less

Authors:
 [1];  [2];  [3];  [4];  [2];  [2];  [2];  [2];  [2];  [2];  [4];  [4];  [4]
  1. Brookhaven National Lab. (BNL), Upton, NY (United States); Idaho State Univ., Pocatello, ID (United States)
  2. Brookhaven National Lab. (BNL), Upton, NY (United States)
  3. Millsaps College, Jackson, MS (United States)
  4. Univ. of Massachusetts, Lowell, MA (United States)
Publication Date:
Research Org.:
Brookhaven National Lab. (BNL), Upton, NY (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Nuclear Physics (NP) (SC-26)
OSTI Identifier:
1337635
Report Number(s):
BNL-113184-2016-JA
Journal ID: ISSN 2100-014X; R&D Project: EST-003-NEFA; KB0301041
Grant/Contract Number:  
SC0012704
Resource Type:
Accepted Manuscript
Journal Name:
EPJ Web of Conferences
Additional Journal Information:
Journal Volume: 146; Journal ID: ISSN 2100-014X
Publisher:
EDP Sciences
Country of Publication:
United States
Language:
English
Subject:
73 NUCLEAR PHYSICS AND RADIATION PHYSICS

Citation Formats

Smith, Suzanne V., Mccutchan, Elizabeth, Gurdal, Gulhan, Lister, Christopher, Muench, Lisa, Nino, Michael, Sonzogni, Alexandro, Herman, Michael, Nobre, Gustavo, Cullen, Chris, Chillery, Thomas, Chowdury, Partha, and Harding, Robert. Production of platinum radioisotopes at Brookhaven Linac Isotope Producer (BLIP). United States: N. p., 2017. Web. doi:10.1051/epjconf/201714609029.
Smith, Suzanne V., Mccutchan, Elizabeth, Gurdal, Gulhan, Lister, Christopher, Muench, Lisa, Nino, Michael, Sonzogni, Alexandro, Herman, Michael, Nobre, Gustavo, Cullen, Chris, Chillery, Thomas, Chowdury, Partha, & Harding, Robert. Production of platinum radioisotopes at Brookhaven Linac Isotope Producer (BLIP). United States. doi:10.1051/epjconf/201714609029.
Smith, Suzanne V., Mccutchan, Elizabeth, Gurdal, Gulhan, Lister, Christopher, Muench, Lisa, Nino, Michael, Sonzogni, Alexandro, Herman, Michael, Nobre, Gustavo, Cullen, Chris, Chillery, Thomas, Chowdury, Partha, and Harding, Robert. Wed . "Production of platinum radioisotopes at Brookhaven Linac Isotope Producer (BLIP)". United States. doi:10.1051/epjconf/201714609029. https://www.osti.gov/servlets/purl/1337635.
@article{osti_1337635,
title = {Production of platinum radioisotopes at Brookhaven Linac Isotope Producer (BLIP)},
author = {Smith, Suzanne V. and Mccutchan, Elizabeth and Gurdal, Gulhan and Lister, Christopher and Muench, Lisa and Nino, Michael and Sonzogni, Alexandro and Herman, Michael and Nobre, Gustavo and Cullen, Chris and Chillery, Thomas and Chowdury, Partha and Harding, Robert},
abstractNote = {The accelerator production of platinum isotopes was investigated at the Brookhaven Linac Isotope Producer (BLIP). In this paper high purity natural platinum foils were irradiated at 53.2, 65.7, 105.2, 151.9, 162.9 and 173.3 MeV. The irradiated foils were digested in aqua regia and then converted to their hydrochloride salt with concentrated hydrochloric acid before analyzing by gamma spectrometry periodically for at least 10 days post end of bombardment. A wide range of platinum (Pt), gold (Au) and iridiu m (Ir) isotopes were identified. Effective cross sections at BLIP for Pt-188, Pt-189, Pt-191 and Pt-195m were compared to literature and theoretical cross sections determined using Empire-3.2. The majority of the effective cross sections (<70 MeV) confirm those reported in the literature. While the absolute values of the theoretical cross sections were up to a factor of 3 lower, Empire 3.2 modeled thresholds and maxima correlated well with experimental values. Preliminary evaluation into a rapid separation of Pt isotopes from high levels of Ir and Au isotopes proved to be a promising approach for large scale production. In conclusion, this study demonstrated that with the use of isotopically enriched target material accelerator production of selected platinum isotopes is feasible over a wide proton energy range.},
doi = {10.1051/epjconf/201714609029},
journal = {EPJ Web of Conferences},
number = ,
volume = 146,
place = {United States},
year = {2017},
month = {9}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record

Save / Share:

Works referenced in this record:

Personalized medicine for targeted and platinum-based chemotherapy of lung and bladder cancer
journal, February 2013

  • Cimino, George D.; Pan, Chong-xian; Henderson, Paul T.
  • Bioanalysis, Vol. 5, Issue 3
  • DOI: 10.4155/bio.12.325

ESCL8R and LEVIT8R: Software for interactive graphical analysis of HPGe coincidence data sets
journal, July 1995

  • Radford, D. C.
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 361, Issue 1-2
  • DOI: 10.1016/0168-9002(95)00183-2