Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications
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journal
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December 2014 |
Microtubule Assembly: A Review of Progress, Principles, and Perspectives
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book
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January 1984 |
Structural basis for the regulation of tubulin by vinblastine
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journal
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May 2005 |
Molecular characterization of human stathmin expressed in Escherichia coli: site-directed mutagenesis of two phosphorylatable serines (Ser-25 and Ser-63)
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journal
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June 1994 |
cAC10-vcMMAE, an anti-CD30–monomethyl auristatin E conjugate with potent and selective antitumor activity
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journal
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August 2003 |
Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.
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journal
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October 1990 |
Dolastatin 10, a powerful cytostatic peptide derived from a marine animal
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journal
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June 1990 |
Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
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journal
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December 2015 |
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
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journal
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January 2013 |
Microtubules as a target for anticancer drugs
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journal
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April 2004 |
Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
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journal
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August 2009 |
Dynamic instability of microtubule growth
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journal
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November 1984 |
Development of potent monoclonal antibody auristatin conjugates for cancer therapy
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journal
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June 2003 |
Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody-Cytotoxic Drug Conjugate
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journal
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November 2008 |
A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end
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journal
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July 2012 |
Enhanced Activity of Monomethylauristatin F through Monoclonal Antibody Delivery: Effects of Linker Technology on Efficacy and Toxicity
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journal
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January 2006 |
The binding conformation of Taxol in -tubulin: A model based on electron crystallographic density
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journal
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April 2001 |
Structural plasticity of tubulin assembly probed by vinca-domain ligands
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journal
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July 2012 |
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
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journal
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May 2014 |
Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins
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journal
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August 2015 |
The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin
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journal
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September 2011 |
Structural Basis of Microtubule Stabilization by Laulimalide and Peloruside A
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journal
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January 2014 |
Mitosis is not a key target of microtubule agents in patient tumors
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journal
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February 2011 |
Natural products which interact with tubulin in the vinca domain: Maytansine, rhizoxin, phomopsin a, dolastatins 10 and 15 and halichondrin B
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journal
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January 1992 |
Structural insight into the inhibition of tubulin by vinca domain peptide ligands
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journal
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September 2008 |
Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP.
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journal
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October 1992 |
The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization
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journal
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April 2014 |
A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
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journal
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August 2014 |
The Dolastatins
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book
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January 1997 |
Structural basis of tubulin tyrosination by tubulin tyrosine ligase
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journal
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January 2013 |
Microtubule Polymerization Dynamics
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journal
|
November 1997 |
Large Scale Purification of Brain Tubulin With the Modified Weisenberg Procedure
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book
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January 2007 |
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
|
journal
|
March 2004 |
Structural Basis of Microtubule Stabilization by Laulimalide and Peloruside A
|
journal
|
January 2014 |
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
|
journal
|
May 2014 |
Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins
|
journal
|
August 2015 |
The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization
|
journal
|
April 2014 |
Enhanced Activity of Monomethylauristatin F through Monoclonal Antibody Delivery: Effects of Linker Technology on Efficacy and Toxicity
|
journal
|
January 2006 |
Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications
|
journal
|
December 2014 |
Dynamic instability of microtubule growth
|
journal
|
November 1984 |
Structural insight into the inhibition of tubulin by vinca domain peptide ligands
|
journal
|
September 2008 |
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
|
journal
|
March 2004 |
Structural basis for the regulation of tubulin by vinblastine
|
journal
|
May 2005 |
Development of potent monoclonal antibody auristatin conjugates for cancer therapy
|
journal
|
June 2003 |
Microtubules as a target for anticancer drugs
|
journal
|
April 2004 |
Mitosis is not a key target of microtubule agents in patient tumors
|
journal
|
February 2011 |
Molecular characterization of human stathmin expressed in Escherichia coli: site-directed mutagenesis of two phosphorylatable serines (Ser-25 and Ser-63)
|
journal
|
June 1994 |
Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
|
journal
|
August 2009 |
A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end
|
journal
|
July 2012 |
Structural basis of tubulin tyrosination by tubulin tyrosine ligase
|
journal
|
January 2013 |
An MBoC Favorite: Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP
|
journal
|
October 2012 |
Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
|
journal
|
December 2015 |
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
|
journal
|
January 2013 |
Microtubule Polymerization Dynamics
|
journal
|
November 1997 |
The Dawn of the Antibody–Drug Conjugates Era: How T-DM1 Reinvented the Future of Chemotherapy for Solid Tumors
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journal
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October 2022 |
U.S. Food and Drug Administration Approval Summary: Brentuximab Vedotin for the Treatment of Relapsed Hodgkin Lymphoma or Relapsed Systemic Anaplastic Large-Cell Lymphoma
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journal
|
September 2012 |
cAC10-vcMMAE, an anti-CD30–monomethyl auristatin E conjugate with potent and selective antitumor activity
|
journal
|
August 2003 |