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Title: Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1 H )-ones as potent and selective PKC θ inhibitors

Authors:
; ; ; ; ; ; ; ; ; ; ; ; ;
Publication Date:
Grant/Contract Number:
AC02-05CH11231
Type:
Publisher's Accepted Manuscript
Journal Name:
Bioorganic and Medicinal Chemistry
Additional Journal Information:
Journal Volume: 24; Journal Issue: 11; Related Information: CHORUS Timestamp: 2018-09-13 13:57:23; Journal ID: ISSN 0968-0896
Publisher:
Elsevier
Sponsoring Org:
USDOE
Country of Publication:
United Kingdom
Language:
English
OSTI Identifier:
1337404

Katoh, Taisuke, Takai, Takafumi, Yukawa, Takafumi, Tsukamoto, Tetsuya, Watanabe, Etsurou, Mototani, Hideyuki, Arita, Takeo, Hayashi, Hiroki, Nakagawa, Hideyuki, Klein, Michael G., Zou, Hua, Sang, Bi-Ching, Snell, Gyorgy, and Nakada, Yoshihisa. Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1 H )-ones as potent and selective PKC θ inhibitors. United Kingdom: N. p., Web. doi:10.1016/j.bmc.2016.04.008.
Katoh, Taisuke, Takai, Takafumi, Yukawa, Takafumi, Tsukamoto, Tetsuya, Watanabe, Etsurou, Mototani, Hideyuki, Arita, Takeo, Hayashi, Hiroki, Nakagawa, Hideyuki, Klein, Michael G., Zou, Hua, Sang, Bi-Ching, Snell, Gyorgy, & Nakada, Yoshihisa. Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1 H )-ones as potent and selective PKC θ inhibitors. United Kingdom. doi:10.1016/j.bmc.2016.04.008.
Katoh, Taisuke, Takai, Takafumi, Yukawa, Takafumi, Tsukamoto, Tetsuya, Watanabe, Etsurou, Mototani, Hideyuki, Arita, Takeo, Hayashi, Hiroki, Nakagawa, Hideyuki, Klein, Michael G., Zou, Hua, Sang, Bi-Ching, Snell, Gyorgy, and Nakada, Yoshihisa. 2016. "Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1 H )-ones as potent and selective PKC θ inhibitors". United Kingdom. doi:10.1016/j.bmc.2016.04.008.
@article{osti_1337404,
title = {Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1 H )-ones as potent and selective PKC θ inhibitors},
author = {Katoh, Taisuke and Takai, Takafumi and Yukawa, Takafumi and Tsukamoto, Tetsuya and Watanabe, Etsurou and Mototani, Hideyuki and Arita, Takeo and Hayashi, Hiroki and Nakagawa, Hideyuki and Klein, Michael G. and Zou, Hua and Sang, Bi-Ching and Snell, Gyorgy and Nakada, Yoshihisa},
abstractNote = {},
doi = {10.1016/j.bmc.2016.04.008},
journal = {Bioorganic and Medicinal Chemistry},
number = 11,
volume = 24,
place = {United Kingdom},
year = {2016},
month = {6}
}