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Title: Cytoskeletal motor-driven active self-assembly in in vitro systems

Abstract

Molecular motor-driven self-assembly has been an active area of soft matter research for the past decade. Because molecular motors transform chemical energy into mechanical work, systems which employ molecular motors to drive self-assembly processes are able to overcome kinetic and thermodynamic limits on assembly time, size, complexity, and structure. Here, we review the progress in elucidating and demonstrating the rules and capabilities of motor-driven active self-assembly. Lastly, we focus on the types of structures created and the degree of control realized over these structures, and discuss the next steps necessary to achieve the full potential of this assembly mode which complements robotic manipulation and passive self-assembly.

Authors:
 [1];  [2];  [3];  [1];  [2];  [4]
  1. Columbia Univ., New York, NY (United States). Dept. of Biomedical Engineering
  2. Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nanosystems Synthesis/Analysis Dept.
  3. Hokkaido Univ., Sapporo (Japan). Faculty of Science
  4. Hokkaido Univ., Sapporo (Japan). Faculty of Science. Graduate School of Chemical Sciences and Engineering
Publication Date:
Research Org.:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Columbia Univ., New York, NY (United States); Hokkaido Univ., Sapporo (Japan)
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22); US Army Research Office (ARO); Japan Society for the Promotion of Science (Japan)
OSTI Identifier:
1335667
Alternate Identifier(s):
OSTI ID: 1343058
Report Number(s):
SAND-2016-9575J; SAND2016-7201J
Journal ID: ISSN 1744-683X; SMOABF; 649560
Grant/Contract Number:  
AC04-94AL85000; W911NF-13-1-0390; 24104004
Resource Type:
Accepted Manuscript
Journal Name:
Soft Matter
Additional Journal Information:
Journal Volume: 12; Journal Issue: 4; Journal ID: ISSN 1744-683X
Publisher:
Royal Society of Chemistry
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Lam, A. T., VanDelinder, V., Kabir, A. M. R., Hess, H., Bachand, G. D., and Kakugo, A. Cytoskeletal motor-driven active self-assembly in in vitro systems. United States: N. p., 2015. Web. doi:10.1039/c5sm02042e.
Lam, A. T., VanDelinder, V., Kabir, A. M. R., Hess, H., Bachand, G. D., & Kakugo, A. Cytoskeletal motor-driven active self-assembly in in vitro systems. United States. doi:10.1039/c5sm02042e.
Lam, A. T., VanDelinder, V., Kabir, A. M. R., Hess, H., Bachand, G. D., and Kakugo, A. Wed . "Cytoskeletal motor-driven active self-assembly in in vitro systems". United States. doi:10.1039/c5sm02042e. https://www.osti.gov/servlets/purl/1335667.
@article{osti_1335667,
title = {Cytoskeletal motor-driven active self-assembly in in vitro systems},
author = {Lam, A. T. and VanDelinder, V. and Kabir, A. M. R. and Hess, H. and Bachand, G. D. and Kakugo, A.},
abstractNote = {Molecular motor-driven self-assembly has been an active area of soft matter research for the past decade. Because molecular motors transform chemical energy into mechanical work, systems which employ molecular motors to drive self-assembly processes are able to overcome kinetic and thermodynamic limits on assembly time, size, complexity, and structure. Here, we review the progress in elucidating and demonstrating the rules and capabilities of motor-driven active self-assembly. Lastly, we focus on the types of structures created and the degree of control realized over these structures, and discuss the next steps necessary to achieve the full potential of this assembly mode which complements robotic manipulation and passive self-assembly.},
doi = {10.1039/c5sm02042e},
journal = {Soft Matter},
number = 4,
volume = 12,
place = {United States},
year = {2015},
month = {11}
}

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Cited by: 11 works
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