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Title: Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus

Authors:
 [1] ;  [1] ;  [2] ;  [3] ;  [1] ;  [1] ;  [2] ;  [4] ;  [5] ;  [3] ;  [3] ;  [1] ;  [3] ;  [2] ;  [1]
  1. Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States
  2. BioScience at Rice and Department of Chemistry, Rice University, Houston, Texas 77251, United States
  3. Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory, Argonne, Illinois 60439, United States
  4. Department of Biochemistry, University of Wisconsin—Madison, Madison, Wisconsin 53705, United States
  5. BioScience at Rice and Department of Chemistry, Rice University, Houston, Texas 77251, United States, Department of Biotechnology and Bioinformatics, Jaypee University of Information Technology, Waknaghat, Himachal Pradesh, India 173234
Publication Date:
Grant/Contract Number:
AC02-06CH11357
Type:
Published Article
Journal Name:
Biochemistry
Additional Journal Information:
Journal Volume: 55; Journal Issue: 36; Related Information: CHORUS Timestamp: 2017-08-25 04:30:10; Journal ID: ISSN 0006-2960
Publisher:
American Chemical Society
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
OSTI Identifier:
1324326