Carbon nanospikes grown on metal wires as microelectrode sensors for dopamine

Zestos, Alexander G.; Yang, Cheng; Jacobs, Christopher B.; Hensley, Dale; Venton, B. Jill

doi:10.1039/C5AN01467K

Title: Carbon nanospikes grown on metal wires as microelectrode sensors for dopamine

Journal Article · 13 September 2015 · Analyst

DOI: https://doi.org/10.1039/C5AN01467K · OSTI ID:1295130

Zestos, Alexander G. ^[1]; Yang, Cheng ^[1]; Jacobs, Christopher B. ^[2]; Hensley, Dale ^[3]; Venton, B. Jill ^[1]

Univ. of Virginia, Charlottesville, VA (United States)
Univ. of Virginia, Charlottesville, VA (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

Carbon nanomaterials are advantageous as electrodes for neurotransmitter detection, but the difficulty of nanomaterials deposition on electrode substrates limits the reproducibility and future applications. In our study, we used plasma enhanced chemical vapor deposition (PECVD) to directly grow a thin layer of carbon nanospikes (CNS) on cylindrical metal substrates. No catalyst is required and the CNS surface coverage is uniform over the cylindrical metal substrate. We characterized the CNS growth on several metallic substrates including tantalum, niobium, palladium, and nickel wires. Using fast-scan cyclic voltammetry (FSCV), bare metal wires could not detect 1 mu M dopamine while carbon nanospike coated wires could. Moreover, the highest sensitivity and optimized S/N ratio was recorded from carbon nanospike-tantalum (CNS-Ta) microwires grown for 7.5 minutes, which had a LOD of 8 +/- 2 nM for dopamine with FSCV. CNS-Ta microelectrodes were more reversible and had a smaller Delta E-p for dopamine than carbon-fiber microelectrodes, suggesting faster electron transfer kinetics. The kinetics of dopamine redox were adsorption controlled at CNS-Ta microelectrodes and repeated electrochemical measurements displayed stability for up to ten hours in vitro and over a ten day period as well. The oxidation potential was significantly different for ascorbic acid and uric acid compared to dopamine. Finally, growing carbon nanospikes on metal wires is a promising method to produce uniformly-coated, carbon nanostructured cylindrical microelectrodes for sensitive dopamine detection.

View Accepted Manuscript (DOE)

Cite

Export

Save

Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States). Center for Nanophase Materials Sciences (CNMS)

Sponsoring Organization:: USDOE

Grant/Contract Number:: AC05-00OR22725

OSTI ID:: 1295130

Journal Information:: Analyst, Journal Name: Analyst Journal Issue: 21 Vol. 140; ISSN ANALAO; ISSN 0003-2654

Publisher:: Royal Society of ChemistryCopyright Statement

Country of Publication:: United States

Language:: English

References (46)

Catalyst-Free Efficient Growth, Orientation and Biosensing Properties of Multilayer Graphene Nanoflake Films with Sharp Edge Planes Shang, Nai Gui; Papakonstantinou, Pagona; McMullan, Martin Advanced Functional Materials, Vol. 18, Issue 21 https://doi.org/10.1002/adfm.200800951	journal	November 2008
Nanostructuring Platinum Nanoparticles on Multilayered Graphene Petal Nanosheets for Electrochemical Biosensing Claussen, Jonathan C.; Kumar, Anurag; Jaroch, David B. Advanced Functional Materials, Vol. 22, Issue 16 https://doi.org/10.1002/adfm.201200551	journal	May 2012
Electrochemical Properties of Different Carbon-Fiber Microelectrodes Using Fast-Scan Cyclic Voltammetry Huffman, Megan L.; Venton, B. Jill Electroanalysis, Vol. 20, Issue 22 https://doi.org/10.1002/elan.200804343	journal	November 2008
Carbon Nanofiber Electrode for Neurochemical Monitoring Zhang, David A.; Rand, Emily; Marsh, Michael Molecular Neurobiology, Vol. 48, Issue 2 https://doi.org/10.1007/s12035-013-8531-6	journal	August 2013
Parametric analysis of the effects of cocaine and cocaine pretreatment on dopamine release in the nucleus accumbens measured by fast cyclic voltammetry Williams, J. E. G.; Wieczorek, W.; Willner, P. Brain Research, Vol. 678, Issue 1-2 https://doi.org/10.1016/0006-8993(95)00188-V	journal	April 1995
Production of petal-like graphite sheets by hydrogen arc discharge Ando, Y.; Zhao, X.; Ohkohchi, M. Carbon, Vol. 35, Issue 1 https://doi.org/10.1016/S0008-6223(96)00139-X	journal	January 1997
Uniform carbon nanoflake films and their field emissions Shang, N. G.; Au, F. C. K.; Meng, X. M. Chemical Physics Letters, Vol. 358, Issue 3-4 https://doi.org/10.1016/S0009-2614(02)00430-X	journal	May 2002
Critical guidelines for validation of the selectivity of in-vivo chemical microsensors Phillips, Paul E. M.; Wightman, R. Mark TrAC Trends in Analytical Chemistry, Vol. 22, Issue 8 https://doi.org/10.1016/S0165-9936(03)00907-5	journal	September 2003
Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review Yang, Cheng; Denno, Madelaine E.; Pyakurel, Poojan Analytica Chimica Acta, Vol. 887 https://doi.org/10.1016/j.aca.2015.05.049	journal	August 2015
Simultaneous monitoring of dopamine concentration at spatially different brain locations in vivo Zachek, Matthew K.; Takmakov, Pavel; Park, Jinwoo Biosensors and Bioelectronics, Vol. 25, Issue 5 https://doi.org/10.1016/j.bios.2009.10.008	journal	January 2010
A carbon nanofiber based biosensor for simultaneous detection of dopamine and serotonin in the presence of ascorbicacid Rand, Emily; Periyakaruppan, Adaikkappan; Tanaka, Zuki Biosensors and Bioelectronics, Vol. 42 https://doi.org/10.1016/j.bios.2012.10.080	journal	April 2013
Growth of conformal single-walled carbon nanotube films from Mo/Fe/Al2O3 deposited by electron beam evaporation Hart, Anastasios John; Slocum, Alexander H.; Royer, Laure Carbon, Vol. 44, Issue 2 https://doi.org/10.1016/j.carbon.2005.07.008	journal	February 2006
Electrochemical methods for ascorbic acid determination Pisoschi, Aurelia Magdalena; Pop, Aneta; Serban, Andreea Iren Electrochimica Acta, Vol. 121 https://doi.org/10.1016/j.electacta.2013.12.127	journal	March 2014
Vertically aligned carbon nanofiber as nano-neuron interface for monitoring neural function Yu, Zhe; McKnight, Timothy E.; Ericson, M. Nance Nanomedicine: Nanotechnology, Biology and Medicine, Vol. 8, Issue 4 https://doi.org/10.1016/j.nano.2012.02.011	journal	May 2012
Epoxy insulated carbon fiber and carbon nanotube fiber microelectrodes Zestos, Alexander G.; Nguyen, Michael D.; Poe, Brian L. Sensors and Actuators B: Chemical, Vol. 182 https://doi.org/10.1016/j.snb.2013.03.066	journal	June 2013
Growth, structure and field emission characteristics of petal like carbon nano-structured thin films Srivastava, Sanjay K.; Shukla, A. K.; Vankar, V. D. Thin Solid Films, Vol. 492, Issue 1-2 https://doi.org/10.1016/j.tsf.2005.07.283	journal	December 2005
Subsecond Adsorption and Desorption of Dopamine at Carbon-Fiber Microelectrodes Bath, Bradley D.; Michael, Darren J.; Trafton, B. Jill Analytical Chemistry, Vol. 72, Issue 24 https://doi.org/10.1021/ac000849y	journal	December 2000
Noise at microelectrodes and microelectrode arrays in amperometry and voltammetry Long, John T.; Weber, Stephen G. Analytical Chemistry, Vol. 60, Issue 20 https://doi.org/10.1021/ac00171a032	journal	October 1988
Resolving Neurotransmitters Detected by Fast-Scan Cyclic Voltammetry Heien, Michael L. A. V.; Johnson, Michael A.; Wightman, R. Mark Analytical Chemistry, Vol. 76, Issue 19 https://doi.org/10.1021/ac0491509	journal	October 2004
Rapid, Sensitive Detection of Neurotransmitters at Microelectrodes Modified with Self-assembled SWCNT Forests Xiao, Ning; Venton, B. Jill Analytical Chemistry, Vol. 84, Issue 18 https://doi.org/10.1021/ac301445w	journal	August 2012
High Temporal Resolution Measurements of Dopamine with Carbon Nanotube Yarn Microelectrodes Jacobs, Christopher B.; Ivanov, Ilia N.; Nguyen, Michael D. Analytical Chemistry, Vol. 86, Issue 12 https://doi.org/10.1021/ac404050t	journal	May 2014
Polyethylenimine Carbon Nanotube Fiber Electrodes for Enhanced Detection of Neurotransmitters Zestos, Alexander G.; Jacobs, Christopher B.; Trikantzopoulos, Elefterios Analytical Chemistry, Vol. 86, Issue 17 https://doi.org/10.1021/ac5003273	journal	August 2014
Carbon Nanopipette Electrodes for Dopamine Detection in Drosophila Rees, Hillary R.; Anderson, Sean E.; Privman, Eve Analytical Chemistry, Vol. 87, Issue 7 https://doi.org/10.1021/ac504596y	journal	March 2015
Carbon Microelectrodes with a Renewable Surface Takmakov, Pavel; Zachek, Matthew K.; Keithley, Richard B. Analytical Chemistry, Vol. 82, Issue 5 https://doi.org/10.1021/ac902753x	journal	March 2010
Nanostructured Carbon Fiber Disk Electrodes for Sensitive Determinations of Adenosine and Uric Acid Brajter-Toth, Anna; El-Nour, Kholoud Abou; Cavalheiro, Eder T. Analytical Chemistry, Vol. 72, Issue 7 https://doi.org/10.1021/ac9906680	journal	April 2000
Contiguous Petal-like Carbon Nanosheet Outgrowths from Graphite Fibers by Plasma CVD Bhuvana, Thiruvelu; Kumar, Anurag; Sood, Aditya ACS Applied Materials & Interfaces, Vol. 2, Issue 3 https://doi.org/10.1021/am9009154	journal	February 2010
Conical Tungsten Tips as Substrates for the Preparation of Ultramicroelectrodes ^† Hermans, Andre; Wightman, R. Mark Langmuir, Vol. 22, Issue 25 https://doi.org/10.1021/la061209e	journal	December 2006
Specific Oxygen-Containing Functional Groups on the Carbon Surface Underlie an Enhanced Sensitivity to Dopamine at Electrochemically Pretreated Carbon Fiber Microelectrodes Roberts, James G.; Moody, Benjamin P.; McCarty, Gregory S. Langmuir, Vol. 26, Issue 11 https://doi.org/10.1021/la9048924	journal	June 2010
Vertically Aligned Carbon Nanofiber Arrays Record Electrophysiological Signals from Hippocampal Slices Yu, Zhe; McKnight, Timothy E.; Ericson, M. Nance Nano Letters, Vol. 7, Issue 8 https://doi.org/10.1021/nl070291a	journal	August 2007
Carbon Nanotube Yarn Electrodes for Enhanced Detection of Neurotransmitter Dynamics in Live Brain Tissue Schmidt, Andreas C.; Wang, Xin; Zhu, Yuntian ACS Nano, Vol. 7, Issue 9 https://doi.org/10.1021/nn402857u	journal	August 2013
Direct growth of aligned carbon nanotubes on bulk metals Talapatra, S.; Kar, S.; Pal, S. K. Nature Nanotechnology, Vol. 1, Issue 2 https://doi.org/10.1038/nnano.2006.56	journal	October 2006
New electrodes for old: from carbon nanotubes to edge plane pyrolytic graphite Banks, Craig E.; Compton, Richard G. The Analyst, Vol. 131, Issue 1 https://doi.org/10.1039/B512688F	journal	January 2006
Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivity Heien, Michael L. A. V.; Phillips, Paul E. M.; Stuber, Garret D. The Analyst, Vol. 128, Issue 12, p. 1413-1419 https://doi.org/10.1039/b307024g	journal	January 2003
Carbon nanotube-modified microelectrodes for simultaneous detection of dopamine and serotonin in vivo Swamy, B. E. Kumara; Venton, B. Jill The Analyst, Vol. 132, Issue 9 https://doi.org/10.1039/b705552h	journal	January 2007
Functional groups modulate the sensitivity and electron transfer kinetics of neurochemicals at carbon nanotube modified microelectrodes Jacobs, Christopher B.; Vickrey, Trisha L.; Venton, B. Jill The Analyst, Vol. 136, Issue 17 https://doi.org/10.1039/c0an00854k	journal	January 2011
Carbon nanofiber electrode array for electrochemical detection of dopamine using fast scan cyclic voltammetry Koehne, Jessica E.; Marsh, Michael; Boakye, Adwoa The Analyst, Vol. 136, Issue 9 https://doi.org/10.1039/c1an15025a	journal	January 2011
Comparison of Nafion- and overoxidized polypyrrole-carbon nanotube electrodes for neurotransmitter detection Peairs, M. Jennifer; Ross, Ashley E.; Venton, B. Jill Analytical Methods, Vol. 3, Issue 10 https://doi.org/10.1039/c1ay05348e	journal	January 2011
A review of plasma enhanced chemical vapour deposition of carbon nanotubes Meyyappan, M. Journal of Physics D: Applied Physics, Vol. 42, Issue 21 https://doi.org/10.1088/0022-3727/42/21/213001	journal	October 2009
Growth and Electrochemical Characterization of Carbon Nanospike Thin Film Electrodes Sheridan, Leah B.; Hensley, Dale K.; Lavrik, Nickolay V. Journal of The Electrochemical Society, Vol. 161, Issue 9 https://doi.org/10.1149/2.0891409jes	journal	January 2014
Plasma-Enhanced Chemical Vapor Deposition of Multiwalled Carbon Nanofibers Matthews, Kristopher; Cruden, Brett A.; Chen, Bin Journal of Nanoscience and Nanotechnology, Vol. 2, Issue 5 https://doi.org/10.1166/153348802760394025	journal	October 2002
Plasma-Enhanced Chemical Vapor Deposition of Multiwalled Carbon Nanofibers Matthews, Kristopher; Cruden, Brett A.; Chen, Bin Journal of Nanoscience and Nanotechnology, Vol. 2, Issue 5 https://doi.org/10.1166/jnn.2002.133	journal	October 2002
Characterization of Spontaneous, Transient Adenosine Release in the Caudate-Putamen and Prefrontal Cortex Nguyen, Michael D.; Lee, Scott T.; Ross, Ashley E. PLoS ONE, Vol. 9, Issue 1 https://doi.org/10.1371/journal.pone.0087165	journal	January 2014
Carbon Microelectrodes with a Renewable Surface K., Zachek, Matthew; Carrie, Donley,; B., Keithley, Richard The University of North Carolina at Chapel Hill University Libraries https://doi.org/10.17615/dkzq-5b82	text	January 2010
Conical Tungsten Tips as Substrates for the Preparation of Ultramicroelectrodes † Andre, Hermans,; Mark, Wightman, R. The University of North Carolina at Chapel Hill University Libraries https://doi.org/10.17615/e96b-gw46	text	January 2006
Simultaneous monitoring of dopamine concentration at spatially different brain locations in vivo K., Zachek, Matthew; Mark, Wightman, R.; S., McCarty, Gregory The University of North Carolina at Chapel Hill University Libraries https://doi.org/10.17615/ff6w-k672	text	January 2010
Catalytic CVD Synthesis of Carbon Nanotubes: Towards High Yield and Low Temperature Growth Magrez, Arnaud; Seo, Jin Won; Smajda, Rita Materials, Vol. 3, Issue 11 https://doi.org/10.3390/ma3114871	journal	November 2010

Cited By (7)

Review: new insights into optimizing chemical and 3D surface structures of carbon electrodes for neurotransmitter detection Cao, Qun; Puthongkham, Pumidech; Venton, B. Jill Analytical Methods, Vol. 11, Issue 3 https://doi.org/10.1039/c8ay02472c	journal	January 2019
Polymer modified carbon fiber-microelectrodes and waveform modifications enhance neurotransmitter metabolite detection Raju, Dilpreet; Mendoza, Alexander; Wonnenberg, Pauline Analytical Methods, Vol. 11, Issue 12 https://doi.org/10.1039/c8ay02737d	journal	January 2019
Recent advances in fast-scan cyclic voltammetry Puthongkham, Pumidech; Venton, B. Jill The Analyst, Vol. 145, Issue 4 https://doi.org/10.1039/c9an01925a	journal	January 2020
Carbon Nanotubes, Nanofibers and Nanospikes for Electrochemical Sensing: A Review Shanta, Aysha S.; Al Mamun, Khandakar A.; Islam, Syed K. The 25th Annual Symposium of Connecticut Microelectronics and Optoelectronics Consortium (CMOC 2016) https://doi.org/10.1142/9789813232341_0003	conference	October 2017
Carbon Nanotubes, Nanofibers and Nanospikes for Electrochemical Sensing: A Review Shanta, Aysha S.; Al Mamun, Khandakar A.; Islam, Syed K. International Journal of High Speed Electronics and Systems, Vol. 26, Issue 03 https://doi.org/10.1142/s0129156417400080	journal	June 2017
Carbon Nanoelectrodes for the Electrochemical Detection of Neurotransmitters Zestos, Alexander G. International Journal of Electrochemistry, Vol. 2018 https://doi.org/10.1155/2018/3679627	journal	August 2018
Recent Advances in the Detection of Neurotransmitters Si, Bo; Song, Edward Chemosensors, Vol. 6, Issue 1 https://doi.org/10.3390/chemosensors6010001	journal	January 2018

Similar Records

Carbon nanotubes grown on metal microelectrodes for the detection of dopamine

Journal Article · 2015 · Analytical Chemistry · OSTI ID:1241476

Yang, Cheng; Jacobs, Christopher B.; Nguyen, Michael; +7 more

Carbon nanospikes have better electrochemical properties than carbon nanotubes due to greater surface roughness and defect sites

Journal Article · 2019 · Carbon · OSTI ID:1560398

Cao, Qun; Hensley, Dale K.; Lavrik, Nickolay V.; +1 more

Carbon nanospike coated nanoelectrodes for measurements of neurotransmitters

Journal Article · 2021 · Faraday Discussions · OSTI ID:2502201

Cao, Qun; Shao, Zijun; Hensley, Dale; +1 more

Related Subjects

36 MATERIALS SCIENCE

Title: Carbon nanospikes grown on metal wires as microelectrode sensors for dopamine

Citation Formats

References (46)

Cited By (7)

Similar Records

Related Subjects