Therapeutic advances in idiopathic pulmonary fibrosis
|
journal
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November 2015 |
A methodology for performing global uncertainty and sensitivity analysis in systems biology
|
journal
|
September 2008 |
Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions
|
journal
|
January 2007 |
TGF-β1 as an Enhancer of Fas-Mediated Apoptosis of Lung Epithelial Cells
|
journal
|
June 2002 |
Multiscale Computational Modeling Reveals a Critical Role for TNF-α Receptor 1 Dynamics in Tuberculosis Granuloma Formation
|
journal
|
February 2011 |
Prostaglandin E 2 Synthesis and Suppression of Fibroblast Proliferation by Alveolar Epithelial Cells Is Cyclooxygenase-2–Dependent
|
journal
|
December 2002 |
Systems Pharmacology Approach Toward the Design of Inhaled Formulations of Rifampicin and Isoniazid for Treatment of Tuberculosis: Design of Inhaled Formulations for Treatment of TB
|
journal
|
March 2015 |
Regulation of Immune Responses by Tgf-β
|
journal
|
April 1998 |
Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity
|
journal
|
September 2001 |
Drug-induced pulmonary fibrosis.
|
journal
|
April 1984 |
Oxidative stress enhanced the transforming growth factor-β2-induced epithelial-mesenchymal transition through chemokine ligand 1 on ARPE-19 cell
|
journal
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March 2020 |
IL-4, IL-13, and dexamethasone augment fibroblast proliferation in asthma
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journal
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April 2001 |
Idiopathic Pulmonary Fibrosis: Pathogenesis and Therapeutic Approaches
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journal
|
January 2004 |
The epithelium in idiopathic pulmonary fibrosis: breaking the barrier
|
journal
|
January 2014 |
MOUSE CD1-SPECIFIC NK1 T CELLS: Development, Specificity, and Function
|
journal
|
April 1997 |
Computational Modeling Predicts IL-10 Control of Lesion Sterilization by Balancing Early Host Immunity–Mediated Antimicrobial Responses with Caseation during Mycobacterium tuberculosis Infection
|
journal
|
December 2014 |
Role of NADPH oxidases in the redox biology of liver fibrosis
|
journal
|
December 2015 |
Traveling Wave Model to Interpret a Wound-Healing Cell Migration Assay for Human Peritoneal Mesothelial Cells
|
journal
|
March 2004 |
Fibroblasts in fibrosis: novel roles and mediators
|
journal
|
May 2014 |
Multi-Scale Modeling Predicts a Balance of Tumor Necrosis Factor-α and Interleukin-10 Controls the Granuloma Environment during Mycobacterium tuberculosis Infection
|
journal
|
July 2013 |
Mechanisms of fibrosis in coal workers' pneumoconiosis. Increased production of platelet-derived growth factor, insulin-like growth factor type I, and transforming growth factor beta and relationship to disease severity.
|
journal
|
October 1994 |
Isolation and primary culture of murine alveolar type II cells.
|
journal
|
April 1996 |
Evaluation of health-related quality-of-life and dyspnea scales in patients with idiopathic pulmonary fibrosis. Correlation with pulmonary function tests
|
journal
|
April 2005 |
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
|
journal
|
April 2008 |
Involvement of Epithelial Cell Apoptosis in Interstitial Lung Diseases
|
journal
|
January 2008 |
A Novel, Non-Prostanoid EP2 Receptor-Selective Prostaglandin E2 Agonist Stimulates Local Bone Formation and Enhances Fracture Healing
|
journal
|
November 2003 |
Biochemical Pathways of Caspase Activation During Apoptosis
|
journal
|
November 1999 |
Is Nox4 a key regulator of the activated state of fibroblasts in systemic sclerosis?
|
journal
|
September 2014 |
Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-β in human normal lung epithelial cells
|
journal
|
October 1998 |
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
|
journal
|
April 2008 |
What Differentiates Normal Lung Repair and Fibrosis?: Inflammation, Resolution of Repair, and Fibrosis
|
journal
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April 2008 |
Cellular Mechanisms of Fatal Early-Onset Autoimmunity in Mice with the T Cell-Specific Targeting of Transforming Growth Factor-β Receptor
|
journal
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September 2006 |
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
|
journal
|
July 1993 |
Health-related quality of life in patients with idiopathic pulmonary fibrosis. What is the main contributing factor?
|
journal
|
April 2005 |
Recent Developments in Myofibroblast Biology
|
journal
|
April 2012 |
Combining experiments with multi-cell agent-based modeling to study biological tissue patterning
|
journal
|
March 2007 |
Pathogenesis, current treatments and future directions for idiopathic pulmonary fibrosis
|
journal
|
June 2013 |
Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis [Correction]
|
journal
|
August 2015 |
The epithelium in idiopathic pulmonary fibrosis: breaking the barrier
|
journal
|
January 2014 |
Idiopathic Pulmonary Fibrosis: Pathogenesis and Therapeutic Approaches
|
journal
|
January 2004 |
Deficient repair response of IPF fibroblasts in a co-culture model of epithelial injury and repair
|
journal
|
January 2014 |
Diminished Prostaglandin E 2 Contributes to the Apoptosis Paradox in Idiopathic Pulmonary Fibrosis
|
journal
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July 2010 |
Pirfenidone: an update on clinical trial data and insights from everyday practice
|
journal
|
February 2014 |
Identification of specific EP receptors responsible for the hemodynamic effects of PGE2
|
journal
|
September 1999 |
A New Hope for Idiopathic Pulmonary Fibrosis
|
journal
|
May 2014 |
Therapeutic advances in idiopathic pulmonary fibrosis
|
journal
|
November 2015 |
Multiscale Computational Modeling Reveals a Critical Role for TNF-α Receptor 1 Dynamics in Tuberculosis Granuloma Formation
|
journal
|
February 2011 |
Regulation of immunity by self-reactive T cells
|
journal
|
June 2005 |
Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity
|
journal
|
September 2001 |
Pirfenidone: an update on clinical trial data and insights from everyday practice
|
journal
|
February 2014 |
Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2
|
journal
|
August 2015 |
Integration of TGF- β - and EGFR-based signaling pathways using an agent-based model of epithelial restitution: An agent-based model of epithelial restitution
|
journal
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October 2012 |
Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action
|
journal
|
October 1988 |
Regulation of Immune Responses by Tgf-β
|
journal
|
April 1998 |
The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system
|
journal
|
June 2008 |
TGF-β type II receptor–deficient thymocytes develop normally but demonstrate increased CD8+ proliferation in vivo
|
journal
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December 2005 |
Synergy between Individual TNF-Dependent Functions Determines Granuloma Performance for Controlling Mycobacterium tuberculosis Infection
|
journal
|
March 2009 |
Identifying Mechanisms of Homeostatic Signaling in Fibroblast Differentiation
|
journal
|
August 2015 |
IL-4, IL-13, and dexamethasone augment fibroblast proliferation in asthma
|
journal
|
April 2001 |
T Cell-Produced Transforming Growth Factor-β1 Controls T Cell Tolerance and Regulates Th1- and Th17-Cell Differentiation
|
journal
|
May 2007 |
Tissue repair and the dynamics of the extracellular matrix
|
journal
|
June 2004 |
Incidence and Prevalence of Idiopathic Pulmonary Fibrosis
|
journal
|
October 2006 |
Wound healing: an overview of acute, fibrotic and delayed healing
|
journal
|
January 2004 |
Stimulation of prostaglandin (PG) F2α and PGE2 release by tumour necrosis factor-α and interleukin-1α in cultured human luteal phase endometrial cells
|
journal
|
October 1995 |
Agent-Based Computational Modeling of Wounded Epithelial Cell Monolayers
|
journal
|
September 2004 |
Pirfenidone: A Novel Anti-fibrotic Agent and Progressive Chronic Allograft Rejection
|
journal
|
October 2002 |
Pharmacological treatment of idiopathic pulmonary fibrosis – preclinical and clinical studies of pirfenidone, nintedanib, and N-acetylcysteine
|
journal
|
January 2015 |
Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis
|
journal
|
April 2015 |
Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model
|
journal
|
December 2004 |
Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis
|
journal
|
January 2008 |
Deficient repair response of IPF fibroblasts in a co-culture model of epithelial injury and repair
|
journal
|
January 2014 |
PGE 2 inhibition of TGF-β1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling
|
journal
|
August 2007 |
The clinical significance of 5% change in vital capacity in patients with idiopathic pulmonary fibrosis: extended analysis of the pirfenidone trial
|
journal
|
December 2011 |
Recent Developments in Myofibroblast Biology
|
journal
|
April 2012 |
The relative balance of GM-CSF and TGF-β1 regulates lung epithelial barrier function
- Overgaard, Christian E.; Schlingmann, Barbara; Dorsainvil White, StevenClaude
-
American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 308, Issue 12
https://doi.org/10.1152/ajplung.00042.2014
|
journal
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June 2015 |
The Wound Healing Process: An Overview of the Cellular and Molecular Mechanisms
|
journal
|
October 2009 |
PGE2 receptor EP2 mediates the antagonistic effect of COX‐2 on TGF‐β signaling during mammary tumorigenesis
|
journal
|
November 2009 |
Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-β in human normal lung epithelial cells
|
journal
|
October 1998 |
Prostaglandin E Receptors
|
journal
|
February 2007 |
MOUSE CD1-SPECIFIC NK1 T CELLS: Development, Specificity, and Function
|
journal
|
April 1997 |
Computational Modeling Predicts IL-10 Control of Lesion Sterilization by Balancing Early Host Immunity–Mediated Antimicrobial Responses with Caseation during Mycobacterium tuberculosis Infection
|
journal
|
December 2014 |
Myofibroblasts contribute to but are not necessary for wound contraction
|
journal
|
September 2015 |
Pirfenidone for the treatment of idiopathic pulmonary fibrosis
|
journal
|
November 2013 |
Redox processes inform multivariate transdifferentiation trajectories associated with TGFβ-induced epithelial–mesenchymal transition
|
journal
|
November 2014 |
IL-4 and IL-13 induce myofibroblastic phenotype of human lung fibroblasts through c-Jun NH2-terminal kinase–dependent pathway
|
journal
|
June 2001 |
Potential Action of IL-4 and IL-13 as Fibrogenic Factors on Lung Fibroblasts in vitro
|
journal
|
January 2003 |
Quality of life of idiopathic pulmonary fibrosis patients
|
journal
|
May 2001 |
TGF-β-induced EMT: mechanisms and implications for fibrotic lung disease
|
journal
|
September 2007 |
Quality of life and dyspnoea in patients treated with bosentan for idiopathic pulmonary fibrosis (BUILD-1)
|
journal
|
August 2009 |
Regulation of immunity by self-reactive T cells
|
journal
|
June 2005 |
Consequences of altered TGF-β expression and responsiveness in breast cancer: evidence for autocrine and paracrine effects
|
journal
|
January 2002 |
Prostaglandin E 2 Inhibits Fibroblast to Myofibroblast Transition via E. Prostanoid Receptor 2 Signaling and Cyclic Adenosine Monophosphate Elevation
|
journal
|
November 2003 |
The Myofibroblast
|
journal
|
June 2007 |
Agent‐based models in translational systems biology
|
journal
|
September 2009 |
Stimulation of prostaglandin (PG) F2α and PGE2 release by tumour necrosis factor-α and interleukin-1α in cultured human luteal phase endometrial cells
|
journal
|
October 1995 |
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
|
journal
|
July 1993 |
Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta.
|
journal
|
August 1988 |
The Wound Healing Process: An Overview of the Cellular and Molecular Mechanisms
|
journal
|
October 2009 |
Is Nox4 a key regulator of the activated state of fibroblasts in systemic sclerosis?
|
journal
|
September 2014 |
Health-related Quality of Life in Patients with Idiopathic Pulmonary Fibrosis -Cross-sectional and Longitudinal Study-
|
journal
|
January 2007 |
Epithelial repair mechanisms in the lung
|
journal
|
June 2010 |
The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system
|
journal
|
June 2008 |
Factors Affecting Wound Healing
|
journal
|
February 2010 |
Bone marrow transplantation alters lung antigen-presenting cells to promote TH17 response and the development of pneumonitis and fibrosis following gammaherpesvirus infection
|
journal
|
September 2015 |
Idiopathic pulmonary fibrosis: multiple causes and multiple mechanisms?
|
journal
|
November 2007 |
The role of airway epithelial cells and innate immune cells in chronic respiratory disease
|
journal
|
September 2014 |
Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution.
|
journal
|
December 1990 |
Pharmacological treatment of idiopathic pulmonary fibrosis – preclinical and clinical studies of pirfenidone, nintedanib, and N-acetylcysteine
|
journal
|
January 2015 |
Airway Epithelial Cells: Current Concepts and Challenges
|
journal
|
September 2008 |
Multiscale agent-based cancer modeling
|
journal
|
September 2008 |
State of the art in the diagnosis and management of interstitial lung disease
|
journal
|
April 2015 |
Multi-Scale Modeling Predicts a Balance of Tumor Necrosis Factor-α and Interleukin-10 Controls the Granuloma Environment during Mycobacterium tuberculosis Infection
|
journal
|
July 2013 |
Redox processes inform multivariate transdifferentiation trajectories associated with TGFβ-induced epithelial–mesenchymal transition
|
journal
|
November 2014 |
Pirfenidone for the treatment of idiopathic pulmonary fibrosis
|
journal
|
November 2013 |
TGF-β-induced EMT: mechanisms and implications for fibrotic lung disease
|
journal
|
September 2007 |
Strategies for Efficient Numerical Implementation of Hybrid Multi-scale Agent-Based Models to Describe Biological Systems
|
journal
|
November 2014 |
Collagen I matrix turnover is regulated by fibronectin polymerization
|
journal
|
May 2010 |
Efficacy of Nintedanib in Idiopathic Pulmonary Fibrosis across Prespecified Subgroups in INPULSIS
|
journal
|
January 2016 |
Tissue repair and the dynamics of the extracellular matrix
|
journal
|
June 2004 |
Traveling Wave Model to Interpret a Wound-Healing Cell Migration Assay for Human Peritoneal Mesothelial Cells
|
journal
|
March 2004 |
Broad Therapeutic Efficacy of Nintedanib in Idiopathic Pulmonary Fibrosis
|
journal
|
January 2016 |
Role of NADPH oxidases in the redox biology of liver fibrosis
|
journal
|
December 2015 |
Synergistic Induction of Cyclooxygenase-2 by Transforming Growth Factor-β1 and Epidermal Growth Factor Inhibits Apoptosis in Epithelial Cells
|
journal
|
December 1999 |
PGE 2 inhibition of TGF-β1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling
|
journal
|
August 2007 |
Quality of life and dyspnoea in patients treated with bosentan for idiopathic pulmonary fibrosis (BUILD-1)
|
journal
|
August 2009 |
Emerging Patterns in Tumor Systems: Simulating the Dynamics of Multicellular Clusters with an Agent-based Spatial Agglomeration Model
|
journal
|
December 2002 |
Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions
|
journal
|
January 2007 |
Drug-induced pulmonary fibrosis.
|
journal
|
April 1984 |
IL-4 and IL-13 induce myofibroblastic phenotype of human lung fibroblasts through c-Jun NH2-terminal kinase–dependent pathway
|
journal
|
June 2001 |
Systems Pharmacology Approach Toward the Design of Inhaled Formulations of Rifampicin and Isoniazid for Treatment of Tuberculosis: Design of Inhaled Formulations for Treatment of TB
|
journal
|
March 2015 |
A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
|
journal
|
May 2014 |
TGF-β1 as an Enhancer of Fas-Mediated Apoptosis of Lung Epithelial Cells
|
journal
|
June 2002 |
Sensitivity Analyses of the Change in FVC in a Phase 3 Trial of Pirfenidone for Idiopathic Pulmonary Fibrosis
|
journal
|
July 2015 |
Health-Related Quality of Life and 6 Min Walk Distance in Patients with Idiopathic Pulmonary Fibrosis
|
journal
|
January 2011 |
Isolation and primary culture of murine alveolar type II cells.
|
journal
|
April 1996 |
Evaluation of health-related quality-of-life and dyspnea scales in patients with idiopathic pulmonary fibrosis. Correlation with pulmonary function tests
|
journal
|
April 2005 |
Bone marrow transplantation alters lung antigen-presenting cells to promote TH17 response and the development of pneumonitis and fibrosis following gammaherpesvirus infection
|
journal
|
September 2015 |
Quality of life of idiopathic pulmonary fibrosis patients
|
journal
|
May 2001 |
Emerging Patterns in Tumor Systems: Simulating the Dynamics of Multicellular Clusters with an Agent-based Spatial Agglomeration Model
|
journal
|
December 2002 |
General Principles of Wound Healing
|
journal
|
June 1997 |
Potential Action of IL-4 and IL-13 as Fibrogenic Factors on Lung Fibroblasts in vitro
|
journal
|
January 2003 |
Health-related quality of life in patients with idiopathic pulmonary fibrosis: a systematic review
|
journal
|
July 2005 |
Viral Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis
|
journal
|
June 2011 |
Combining experiments with multi-cell agent-based modeling to study biological tissue patterning
|
journal
|
March 2007 |
Synergistic Induction of Cyclooxygenase-2 by Transforming Growth Factor-β1 and Epidermal Growth Factor Inhibits Apoptosis in Epithelial Cells
|
journal
|
December 1999 |
Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model
|
journal
|
December 2004 |
Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases
|
journal
|
June 2002 |
PGE2 receptor EP2 mediates the antagonistic effect of COX‐2 on TGF‐β signaling during mammary tumorigenesis
|
journal
|
November 2009 |
Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis
|
journal
|
April 2015 |
Regulation of local immunity by airway epithelial cells
|
journal
|
December 2007 |
The relative balance of GM-CSF and TGF-β1 regulates lung epithelial barrier function
- Overgaard, Christian E.; Schlingmann, Barbara; Dorsainvil White, StevenClaude
-
American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 308, Issue 12
https://doi.org/10.1152/ajplung.00042.2014
|
journal
|
June 2015 |
Health-related quality of life in patients with idiopathic pulmonary fibrosis. What is the main contributing factor?
|
journal
|
April 2005 |
The role of airway epithelial cells and innate immune cells in chronic respiratory disease
|
journal
|
September 2014 |
A Novel, Non-Prostanoid EP2 Receptor-Selective Prostaglandin E2 Agonist Stimulates Local Bone Formation and Enhances Fracture Healing
|
journal
|
November 2003 |
Involvement of Epithelial Cell Apoptosis in Interstitial Lung Diseases
|
journal
|
January 2008 |
Multiscale agent-based cancer modeling
|
journal
|
September 2008 |
Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE 2
|
journal
|
February 2003 |
Biochemical Pathways of Caspase Activation During Apoptosis
|
journal
|
November 1999 |
Mechanisms of fibrosis in coal workers' pneumoconiosis. Increased production of platelet-derived growth factor, insulin-like growth factor type I, and transforming growth factor beta and relationship to disease severity.
|
journal
|
October 1994 |
Agent-based model of inflammation and wound healing: insights into diabetic foot ulcer pathology and the role of transforming growth factor-β1
|
journal
|
September 2007 |
Health-related Quality of Life in Patients with Idiopathic Pulmonary Fibrosis -Cross-sectional and Longitudinal Study-
|
journal
|
January 2007 |
Myofibroblast Differentiation by Transforming Growth Factor-β1 Is Dependent on Cell Adhesion and Integrin Signaling via Focal Adhesion Kinase
|
journal
|
January 2003 |
State of the art in the diagnosis and management of interstitial lung disease
|
journal
|
April 2015 |
T Cell-Produced Transforming Growth Factor-β1 Controls T Cell Tolerance and Regulates Th1- and Th17-Cell Differentiation
|
journal
|
May 2007 |
Pirfenidone: A Novel Anti-fibrotic Agent and Progressive Chronic Allograft Rejection
|
journal
|
October 2002 |
Collagen I matrix turnover is regulated by fibronectin polymerization
|
journal
|
May 2010 |
Fibroblasts in fibrosis: novel roles and mediators
|
journal
|
May 2014 |
Pathogenesis, current treatments and future directions for idiopathic pulmonary fibrosis
|
journal
|
June 2013 |
Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
|
journal
|
January 2007 |
Wound healing: an overview of acute, fibrotic and delayed healing
|
journal
|
January 2004 |
Prostaglandin E 2 Synthesis and Suppression of Fibroblast Proliferation by Alveolar Epithelial Cells Is Cyclooxygenase-2–Dependent
|
journal
|
December 2002 |
Strategies for Efficient Numerical Implementation of Hybrid Multi-scale Agent-Based Models to Describe Biological Systems
|
journal
|
November 2014 |
TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains
|
journal
|
June 1990 |
Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta
|
journal
|
August 1988 |
Identifying Mechanisms of Homeostatic Signaling in Fibroblast Differentiation
|
journal
|
August 2015 |
Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2
|
journal
|
August 2015 |
The effect of transforming growth factor-beta on cell proliferation and collagen formation by lung fibroblasts.
|
journal
|
March 1987 |
The Differential Effect of Prostaglandin E2 on Transforming Growth Factor-β and Insulin-induced Collagen Formation in Lung Fibroblasts
|
journal
|
October 1989 |
Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action
|
journal
|
October 1988 |