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Title: VUV action spectroscopy of protonated leucine-enkephalin peptide in the 6-14 eV range

Abstract

We have studied the VUV photodissociation of gas-phase protonated leucine-enkephalin peptide ion in the 5.7 to 14 eV photon energy range by coupling a linear quadrupole ion trap with a synchrotron radiation source. We report VUV activation tandem mass spectra at 6.7, 8.4 and 12.8 eV photon energies and photodissociation yields for a number of selected fragments. The obtained results provide insights into both near VUV radiation damage and electronic properties of a model peptide. We could distinguish several absorption bands and assign them to particular electronic transitions, according to previous theoretical studies. Furthermore, the photodissociation yields appear to be very different for the various observed fragmentation channels, depending both on the type of fragments and their position along the peptide backbone. The present results are discussed in light of recent gas-phase spectroscopic data on peptides.

Authors:
 [1];  [2];  [3];  [4]; ORCiD logo [5]
+ Show Author Affiliations
  1. Univ. of Belgrade, Belgrade (Serbia)
  2. UMR1324 Centre des Sciences du Gout et de l'Alimentation, Dijon (France)
  3. SOLEIL, Gif sur Yvette Cedex (France)
  4. SOLEIL, Gif sur Yvette Cedex (France); INRA, Nantes (France)
  5. Univ. of Belgrade, Belgrade (Serbia); Univ. of Notre Dame, Notre Dame, IN (United States)
Publication Date:
Research Org.:
University of Notre Dame, IN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1234511
Alternate Identifier(s):
OSTI ID: 1234110
Grant/Contract Number:  
FC02-04ER15533
Resource Type:
Accepted Manuscript
Journal Name:
Journal of Chemical Physics
Additional Journal Information:
Journal Volume: 143; Journal Issue: 24; Journal ID: ISSN 0021-9606
Publisher:
American Institute of Physics (AIP)
Country of Publication:
United States
Language:
English
Subject:
74 ATOMIC AND MOLECULAR PHYSICS; action spectroscopy; VUV; leucine-enkephalin; mass spectrometry; photons; peptides; photodissociation; mass spectra; bond cleavage

Citation Formats

Ranković, M. Lj., Canon, F., Nahon, L., Giuliani, A., and Milosavljević, A. R. VUV action spectroscopy of protonated leucine-enkephalin peptide in the 6-14 eV range. United States: N. p., 2015. Web. doi:10.1063/1.4939080.
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Ranković, M. Lj., Canon, F., Nahon, L., Giuliani, A., & Milosavljević, A. R. VUV action spectroscopy of protonated leucine-enkephalin peptide in the 6-14 eV range. United States. https://doi.org/10.1063/1.4939080
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Ranković, M. Lj., Canon, F., Nahon, L., Giuliani, A., and Milosavljević, A. R. Tue . "VUV action spectroscopy of protonated leucine-enkephalin peptide in the 6-14 eV range". United States. https://doi.org/10.1063/1.4939080. https://www.osti.gov/servlets/purl/1234511.
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@article{osti_1234511,
title = {VUV action spectroscopy of protonated leucine-enkephalin peptide in the 6-14 eV range},
author = {Ranković, M. Lj. and Canon, F. and Nahon, L. and Giuliani, A. and Milosavljević, A. R.},
abstractNote = {We have studied the VUV photodissociation of gas-phase protonated leucine-enkephalin peptide ion in the 5.7 to 14 eV photon energy range by coupling a linear quadrupole ion trap with a synchrotron radiation source. We report VUV activation tandem mass spectra at 6.7, 8.4 and 12.8 eV photon energies and photodissociation yields for a number of selected fragments. The obtained results provide insights into both near VUV radiation damage and electronic properties of a model peptide. We could distinguish several absorption bands and assign them to particular electronic transitions, according to previous theoretical studies. Furthermore, the photodissociation yields appear to be very different for the various observed fragmentation channels, depending both on the type of fragments and their position along the peptide backbone. The present results are discussed in light of recent gas-phase spectroscopic data on peptides.},
doi = {10.1063/1.4939080},
journal = {Journal of Chemical Physics},
number = 24,
volume = 143,
place = {United States},
year = {Tue Dec 29 00:00:00 EST 2015},
month = {Tue Dec 29 00:00:00 EST 2015}
}
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https://doi.org/10.1063/1.4939080
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Works referenced in this record:

Principles that Govern the Folding of Protein Chains
journal, July 1973

Investigation of the Amino Acids Glycine, Proline, and Methionine by Photoemission Spectroscopy
journal, November 2007

  • Plekan, Oksana; Feyer, Vitaliy; Richter, Robert
  • The Journal of Physical Chemistry A, Vol. 111, Issue 43
  • DOI: 10.1021/jp075384v

VUV Photodynamics and Chiral Asymmetry in the Photoionization of Gas Phase Alanine Enantiomers
journal, April 2014

  • Tia, Maurice; Cunha de Miranda, Barbara; Daly, Steven
  • The Journal of Physical Chemistry A, Vol. 118, Issue 15
  • DOI: 10.1021/jp5016142

Thermal Vaporization of Biological Nanoparticles:  Fragment-Free Vacuum Ultraviolet Photoionization Mass Spectra of Tryptophan, Phenylalanine−Glycine−Glycine, and β-Carotene
journal, February 2006

  • Wilson, Kevin R.; Jimenez-Cruz, Michael; Nicolas, Christophe
  • The Journal of Physical Chemistry A, Vol. 110, Issue 6
  • DOI: 10.1021/jp0543734

Vacuum-Ultraviolet Photoionization Studies of the Microhydration of DNA Bases (Guanine, Cytosine, Adenine, and Thymine) †
journal, August 2007

  • Belau, Leonid; Wilson, Kevin R.; Leone, Stephen R.
  • The Journal of Physical Chemistry A, Vol. 111, Issue 31
  • DOI: 10.1021/jp0705929

Modeling Photoionization of Aqueous DNA and Its Components
journal, March 2015

  • Pluhařová, Eva; Slavíček, Petr; Jungwirth, Pavel
  • Accounts of Chemical Research, Vol. 48, Issue 5
  • DOI: 10.1021/ar500366z

Microhydration Effects on the Ultrafast Photodynamics of Cytosine: Evidences for a Possible Hydration-Site Dependence
journal, October 2015

  • Ho, Jr-Wei; Yen, Hung-Chien; Shi, Hui-Qi
  • Angewandte Chemie International Edition, Vol. 54, Issue 49
  • DOI: 10.1002/anie.201507524

Photoionization of a protein isolated in vacuo
journal, January 2011

  • Milosavljević, Aleksandar R.; Nicolas, Christophe; Lemaire, Joel
  • Physical Chemistry Chemical Physics, Vol. 13, Issue 34
  • DOI: 10.1039/c1cp21211g

Photodissociation of protonated leucine-enkephalin in the VUV range of 8–40 eV
journal, January 2011

  • Bari, S.; Gonzalez-Magaña, O.; Reitsma, G.
  • The Journal of Chemical Physics, Vol. 134, Issue 2
  • DOI: 10.1063/1.3515301

Contribution of synchrotron radiation to photoactivation studies of biomolecular ions in the gas phase: ION ACTIVATION BY SYNCHROTRON RADIATION
journal, December 2013

  • Giuliani, Alexandre; Milosavljević, Aleksandar R.; Canon, Francis
  • Mass Spectrometry Reviews, Vol. 33, Issue 6
  • DOI: 10.1002/mas.21398

Gas phase Photo-Formation and Vacuum UV Photofragmentation Spectroscopy of Tryptophan and Tyrosine Radical-Containing Peptides
journal, August 2011

  • Brunet, Claire; Antoine, Rodolphe; Allouche, Abdul-Rahman
  • The Journal of Physical Chemistry A, Vol. 115, Issue 32
  • DOI: 10.1021/jp205617x

Electrospray: From ions in solution to ions in the gas phase, what we know now
journal, November 2009

  • Kebarle, Paul; Verkerk, Udo H.
  • Mass Spectrometry Reviews, Vol. 28, Issue 6
  • DOI: 10.1002/mas.20247

Leucine enkephalin-A mass spectrometry standard
journal, July 2010

  • Sztáray, Judit; Memboeuf, Antony; Drahos, László
  • Mass Spectrometry Reviews, Vol. 30, Issue 2
  • DOI: 10.1002/mas.20279

Nanosolvation-Induced Stabilization of a Protonated Peptide Dimer Isolated in the Gas Phase
journal, June 2013

  • Milosavljević, Aleksandar R.; Cerovski, Viktor Z.; Canon, Francis
  • Angewandte Chemie International Edition, Vol. 52, Issue 28
  • DOI: 10.1002/anie.201301667

VUV photofragmentation of protonated leucine-enkephalin peptide dimer below ionization energy
journal, March 2014

  • Milosavljević, Aleksandar R.; Cerovski, Viktor Z.; Ranković, Miloš Lj.
  • The European Physical Journal D, Vol. 68, Issue 3
  • DOI: 10.1140/epjd/e2014-40826-y

Action spectroscopy of a protonated peptide in the ultraviolet range
journal, January 2015

  • Canon, Francis; Milosavljević, Aleksandar R.; Nahon, Laurent
  • Physical Chemistry Chemical Physics, Vol. 17, Issue 39
  • DOI: 10.1039/C4CP04762A

DESIRS: a state-of-the-art VUV beamline featuring high resolution and variable polarization for spectroscopy and dichroism at SOLEIL
journal, May 2012

  • Nahon, Laurent; de Oliveira, Nelson; Garcia, Gustavo A.
  • Journal of Synchrotron Radiation, Vol. 19, Issue 4
  • DOI: 10.1107/S0909049512010588

Fast in vacuo photon shutter for synchrotron radiation quadrupole ion trap tandem mass spectrometry
journal, May 2012

  • Milosavljević, A. R.; Nicolas, C.; Gil, J. -F.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 279
  • DOI: 10.1016/j.nimb.2011.10.032

Letter to the editors
journal, November 1984

Theoretical Study of the Electronic Spectroscopy of Peptides. 1. The Peptidic Bond:  Primary, Secondary, and Tertiary Amides
journal, January 1996

  • Serrano-Andrés, Luis; Fülscher, Markus P.
  • Journal of the American Chemical Society, Vol. 118, Issue 48
  • DOI: 10.1021/ja961996+

Theoretical Study of the Electronic Spectroscopy of Peptides. 2. Glycine and N -Acetylglycine
journal, January 1996

  • Serrano-Andrés, Luis; Fülscher, Markus P.
  • Journal of the American Chemical Society, Vol. 118, Issue 48
  • DOI: 10.1021/ja9619972

Theoretical Study of the Electronic Spectroscopy of Peptides. III. Charge-Transfer Transitions in Polypeptides
journal, October 1998

  • Serrano-Andrés, Luis; Fülscher, Markus P.
  • Journal of the American Chemical Society, Vol. 120, Issue 42
  • DOI: 10.1021/ja981148+

Charge Transfer Transitions in Neutral and Ionic Polypeptides:  A Theoretical Study
journal, September 2001

  • Serrano-Andrés, Luis; Fülscher, Markus P.
  • The Journal of Physical Chemistry B, Vol. 105, Issue 38
  • DOI: 10.1021/jp0034473

Length effects in VUV photofragmentation of protonated peptides
journal, January 2012

  • González-Magaña, O.; Reitsma, G.; Bari, S.
  • Physical Chemistry Chemical Physics, Vol. 14, Issue 13
  • DOI: 10.1039/c2cp23470j

Infrared Spectroscopy and Theoretical Studies on Gas-Phase Protonated Leu-enkephalin and Its Fragments:  Direct Experimental Evidence for the Mobile Proton
journal, May 2007

  • Polfer, Nick C.; Oomens, Jos; Suhai, Sándor
  • Journal of the American Chemical Society, Vol. 129, Issue 18
  • DOI: 10.1021/ja068014d

Photoinduced fragmentation of gas-phase protonated leucine- enkephalin peptide in the VUV range
journal, September 2015

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