skip to main content

DOE PAGESDOE PAGES

Title: The life science X-ray scattering beamline at NSLS-II

We report the current development status of the High Brightness X-ray Scattering for Life Sciences (or Life Science X-ray Scattering, LiX) beamline at the NSLS-II facility of Brookhaven National Laboratory. This instrument will operate in the x-ray energy range of 2.1-18 keV, provide variable beam sizes from 1 micron to ~0.5 mm, and support user experiments in three scientific areas: (1) high-throughput solution scattering, in-line size exclusion chromatography and flow mixers-based time-resolved solution scattering of biological macro-molecules, (2) diffraction from single- and multi-layered lipid membranes, and (3) scattering-based scanning probe imaging of biological tissues. In order to satisfy the beam stability required for these experiments and to switch rapidly between different types of experiments, we have adopted a secondary source with refractive lenses for secondary focusing, a detector system consisting of three Pilatus detectors, and specialized experimental modules that can be quickly exchanged and each dedicated to a defined set of experiments. The construction of this beamline is on schedule for completion in September 2015. User experiments are expected to start in Spring 2016.
Authors:
 [1] ;  [1] ;  [1] ;  [1] ;  [1] ;  [1] ;  [2] ;  [1]
  1. Brookhaven National Lab. (BNL), Upton, NY (United States)
  2. Brookhaven National Lab. (BNL), Upton, NY (United States); Institut fur Werkstoffforschung, Hamburg (Germany)
Publication Date:
Report Number(s):
BNL-108470-2015-JA
Journal ID: ISSN 0094-243X; R&D Project: LS001
Grant/Contract Number:
SC00112704
Type:
Accepted Manuscript
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 1741; Conference: Synchrotron Radiation Instrumentation (SRI 2015), New York, NY (United States, 6-10 Jul 2015; Journal ID: ISSN 0094-243X
Publisher:
AIP
Research Org:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Org:
USDOE Office of Science (SC)
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE
OSTI Identifier:
1228834

DiFabio, Jonathan, Yang, Lin, Chodankar, Shirish, Pjerov, Sal, Jakoncic, Jean, Lucas, Michael, Krywka, Christina, and Graziano, Vito. The life science X-ray scattering beamline at NSLS-II. United States: N. p., Web. doi:10.1063/1.4952872.
DiFabio, Jonathan, Yang, Lin, Chodankar, Shirish, Pjerov, Sal, Jakoncic, Jean, Lucas, Michael, Krywka, Christina, & Graziano, Vito. The life science X-ray scattering beamline at NSLS-II. United States. doi:10.1063/1.4952872.
DiFabio, Jonathan, Yang, Lin, Chodankar, Shirish, Pjerov, Sal, Jakoncic, Jean, Lucas, Michael, Krywka, Christina, and Graziano, Vito. 2015. "The life science X-ray scattering beamline at NSLS-II". United States. doi:10.1063/1.4952872. https://www.osti.gov/servlets/purl/1228834.
@article{osti_1228834,
title = {The life science X-ray scattering beamline at NSLS-II},
author = {DiFabio, Jonathan and Yang, Lin and Chodankar, Shirish and Pjerov, Sal and Jakoncic, Jean and Lucas, Michael and Krywka, Christina and Graziano, Vito},
abstractNote = {We report the current development status of the High Brightness X-ray Scattering for Life Sciences (or Life Science X-ray Scattering, LiX) beamline at the NSLS-II facility of Brookhaven National Laboratory. This instrument will operate in the x-ray energy range of 2.1-18 keV, provide variable beam sizes from 1 micron to ~0.5 mm, and support user experiments in three scientific areas: (1) high-throughput solution scattering, in-line size exclusion chromatography and flow mixers-based time-resolved solution scattering of biological macro-molecules, (2) diffraction from single- and multi-layered lipid membranes, and (3) scattering-based scanning probe imaging of biological tissues. In order to satisfy the beam stability required for these experiments and to switch rapidly between different types of experiments, we have adopted a secondary source with refractive lenses for secondary focusing, a detector system consisting of three Pilatus detectors, and specialized experimental modules that can be quickly exchanged and each dedicated to a defined set of experiments. The construction of this beamline is on schedule for completion in September 2015. User experiments are expected to start in Spring 2016.},
doi = {10.1063/1.4952872},
journal = {AIP Conference Proceedings},
number = ,
volume = 1741,
place = {United States},
year = {2015},
month = {9}
}