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Title: Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago

New direct-acting antivirals (DAAs) provide an opportunity to combat hepatitis C virus (HCV) infection in persons who inject drugs (PWID). In our paper, we use a mathematical model to predict the impact of a DAA-treatment scale-up on HCV prevalence among PWID and the estimated cost in metropolitan Chicago.
Authors:
 [1] ;  [1] ;  [2] ;  [3] ;  [4] ;  [1] ;  [4]
  1. Loyola Univ. Chicago, Maywood, IL (United States). Medical Center
  2. Univ. of Illinois, Chicago, IL (United States)
  3. Food and Drug Administration, Silver Spring, MD (United States)
  4. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Publication Date:
Report Number(s):
LA-UR-14-29030
Journal ID: ISSN 1932-6203
Grant/Contract Number:
AC52-06NA25396
Type:
Accepted Manuscript
Journal Name:
PLoS ONE
Additional Journal Information:
Journal Volume: 10; Journal Issue: 8; Journal ID: ISSN 1932-6203
Publisher:
Public Library of Science
Research Org:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES
OSTI Identifier:
1222580
Alternate Identifier(s):
OSTI ID: 1235741

Echevarria, Desarae, Gutfraind, Alexander, Boodram, Basmattee, Major, Marian, Del Valle, Sara, Cotler, Scott J., and Dahari, Harel. Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago. United States: N. p., Web. doi:10.1371/journal.pone.0135901.
Echevarria, Desarae, Gutfraind, Alexander, Boodram, Basmattee, Major, Marian, Del Valle, Sara, Cotler, Scott J., & Dahari, Harel. Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago. United States. doi:10.1371/journal.pone.0135901.
Echevarria, Desarae, Gutfraind, Alexander, Boodram, Basmattee, Major, Marian, Del Valle, Sara, Cotler, Scott J., and Dahari, Harel. 2015. "Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago". United States. doi:10.1371/journal.pone.0135901. https://www.osti.gov/servlets/purl/1222580.
@article{osti_1222580,
title = {Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago},
author = {Echevarria, Desarae and Gutfraind, Alexander and Boodram, Basmattee and Major, Marian and Del Valle, Sara and Cotler, Scott J. and Dahari, Harel},
abstractNote = {New direct-acting antivirals (DAAs) provide an opportunity to combat hepatitis C virus (HCV) infection in persons who inject drugs (PWID). In our paper, we use a mathematical model to predict the impact of a DAA-treatment scale-up on HCV prevalence among PWID and the estimated cost in metropolitan Chicago.},
doi = {10.1371/journal.pone.0135901},
journal = {PLoS ONE},
number = 8,
volume = 10,
place = {United States},
year = {2015},
month = {8}
}