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Title: 24-hour human urine and serum profiles of Bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics

Abstract

Here we present data to evaluate potential absorption of Bisphenol A through non-metabolizing tissues of the upper digestive tract. Concurrent serum and urine concentrations of d6-BPA, and its glucuronide and sulfate conjugates, were measured over a 24 h period in 10 adult male volunteers following ingestion of 30 μg d6-BPA/kg body weight in soup. The pharmacokinetic behavior of BPA and its metabolites in this cohort (rapid absorption, complete elimination, evidence against sublingual absorption) was reported. This Data in Brief article contains the corresponding individual pharmacokinetic data, reports the demographics of the cohort and provides additional details related to the analytical methods employed and is related to [4].

Authors:
ORCiD logo [1];  [2];  [2];  [2];  [2];  [3];  [2]
  1. Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Oregon State Univ., Corvallis, OR (United States)
  2. U.S. Food and Drug Administration, Jefferson, AR (United States)
  3. The Ohio State Univ., Columbus, OH (United States)
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1213564
Report Number(s):
PNNL-ACT-SA-10050
Journal ID: ISSN 2352-3409; PII: S2352340915000360
Grant/Contract Number:  
AC05-76RL01830
Resource Type:
Accepted Manuscript
Journal Name:
Data in Brief
Additional Journal Information:
Journal Volume: 4; Journal Issue: C; Journal ID: ISSN 2352-3409
Publisher:
Elsevier
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Teeguarden, Justin G., Twaddle, Nathan C., Churchwell, Mona I., Yang, Xiaoxia, Fisher, Jeffrey W., Seryak, Liesel M., and Doerge, Daniel R.. 24-hour human urine and serum profiles of Bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics. United States: N. p., 2015. Web. https://doi.org/10.1016/j.dib.2015.03.002.
Teeguarden, Justin G., Twaddle, Nathan C., Churchwell, Mona I., Yang, Xiaoxia, Fisher, Jeffrey W., Seryak, Liesel M., & Doerge, Daniel R.. 24-hour human urine and serum profiles of Bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics. United States. https://doi.org/10.1016/j.dib.2015.03.002
Teeguarden, Justin G., Twaddle, Nathan C., Churchwell, Mona I., Yang, Xiaoxia, Fisher, Jeffrey W., Seryak, Liesel M., and Doerge, Daniel R.. Tue . "24-hour human urine and serum profiles of Bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics". United States. https://doi.org/10.1016/j.dib.2015.03.002. https://www.osti.gov/servlets/purl/1213564.
@article{osti_1213564,
title = {24-hour human urine and serum profiles of Bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics},
author = {Teeguarden, Justin G. and Twaddle, Nathan C. and Churchwell, Mona I. and Yang, Xiaoxia and Fisher, Jeffrey W. and Seryak, Liesel M. and Doerge, Daniel R.},
abstractNote = {Here we present data to evaluate potential absorption of Bisphenol A through non-metabolizing tissues of the upper digestive tract. Concurrent serum and urine concentrations of d6-BPA, and its glucuronide and sulfate conjugates, were measured over a 24 h period in 10 adult male volunteers following ingestion of 30 μg d6-BPA/kg body weight in soup. The pharmacokinetic behavior of BPA and its metabolites in this cohort (rapid absorption, complete elimination, evidence against sublingual absorption) was reported. This Data in Brief article contains the corresponding individual pharmacokinetic data, reports the demographics of the cohort and provides additional details related to the analytical methods employed and is related to [4].},
doi = {10.1016/j.dib.2015.03.002},
journal = {Data in Brief},
number = C,
volume = 4,
place = {United States},
year = {2015},
month = {9}
}

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Works referenced in this record:

Concurrent determination of bisphenol A pharmacokinetics in maternal and fetal rhesus monkeys
journal, February 2013

  • Patterson, Tucker A.; Twaddle, Nathan C.; Roegge, Cindy S.
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24-hour human urine and serum profiles of bisphenol A: Evidence against sublingual absorption following ingestion in soup
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    Works referencing / citing this record:

    Pilot Study on the Effect of Orally Administered Bisphenol A on Glucose and Insulin Response in Nonobese Adults
    journal, February 2019

    • Hagobian, Todd Alan; Bird, Alyssa; Stanelle, Sean
    • Journal of the Endocrine Society, Vol. 3, Issue 3
    • DOI: 10.1210/js.2018-00322

    Exposure assessment to bisphenol A (BPA) in Portuguese children by human biomonitoring
    journal, October 2017

    • Correia-Sá, Luísa; Kasper-Sonnenberg, Monika; Schütze, André
    • Environmental Science and Pollution Research, Vol. 24, Issue 35
    • DOI: 10.1007/s11356-017-0358-7