Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy
Abstract
The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions (heavier than protons). This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes this species an interesting candidate for the laser driven ion source. Two mechanisms (magnetic vortex acceleration and hole-boring radiation pressure acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He3 ions, having almost the same penetration depth as He4 with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.
- Authors:
- Publication Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). Accelerator & Fusion Research Division
- Sponsoring Org.:
- USDOE Office of Science (SC)
- OSTI Identifier:
- 1188514
- Alternate Identifier(s):
- OSTI ID: 1209689; OSTI ID: 1234541
- Report Number(s):
- LBNL-186519
Journal ID: ISSN 1098-4402; PRABFM; 061302
- Grant/Contract Number:
- AC02-05CH11231; FG02-12ER41798; AC02- 05CH11231
- Resource Type:
- Published Article
- Journal Name:
- Physical Review Special Topics. Accelerators and Beams
- Additional Journal Information:
- Journal Name: Physical Review Special Topics. Accelerators and Beams Journal Volume: 18 Journal Issue: 6; Journal ID: ISSN 1098-4402
- Publisher:
- American Physical Society
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 43 PARTICLE ACCELERATORS; 62 RADIOLOGY AND NUCLEAR MEDICINE
Citation Formats
Bulanov, S. S., Esarey, E., Schroeder, C. B., Leemans, W. P., Bulanov, S. V., Margarone, D., Korn, G., and Haberer, T. Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy. United States: N. p., 2015.
Web. doi:10.1103/PhysRevSTAB.18.061302.
Bulanov, S. S., Esarey, E., Schroeder, C. B., Leemans, W. P., Bulanov, S. V., Margarone, D., Korn, G., & Haberer, T. Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy. United States. https://doi.org/10.1103/PhysRevSTAB.18.061302
Bulanov, S. S., Esarey, E., Schroeder, C. B., Leemans, W. P., Bulanov, S. V., Margarone, D., Korn, G., and Haberer, T. Wed .
"Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy". United States. https://doi.org/10.1103/PhysRevSTAB.18.061302.
@article{osti_1188514,
title = {Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy},
author = {Bulanov, S. S. and Esarey, E. and Schroeder, C. B. and Leemans, W. P. and Bulanov, S. V. and Margarone, D. and Korn, G. and Haberer, T.},
abstractNote = {The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions (heavier than protons). This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes this species an interesting candidate for the laser driven ion source. Two mechanisms (magnetic vortex acceleration and hole-boring radiation pressure acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He3 ions, having almost the same penetration depth as He4 with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.},
doi = {10.1103/PhysRevSTAB.18.061302},
journal = {Physical Review Special Topics. Accelerators and Beams},
number = 6,
volume = 18,
place = {United States},
year = {Wed Jun 24 00:00:00 EDT 2015},
month = {Wed Jun 24 00:00:00 EDT 2015}
}
https://doi.org/10.1103/PhysRevSTAB.18.061302
Web of Science
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