Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations
Abstract
Here, a structure for lossless ion manipulation (SLIM) module was constructed with electrode arrays patterned on a pair of parallel printed circuit boards (PCB) separated by 5 mm and utilized to investigate capabilities for ion trapping at 4 Torr. Positive ions were confined by application of RF having alternating phases on a series of inner rung electrodes and by positive DC potentials on surrounding guard electrodes on each PCB. An axial DC field was also introduced by stepwise varying the DC potential of the inner rung electrodes so as to control the ion transport and accumulation inside the ion trap. We show that ions could be trapped and accumulated with 100% efficiency, stored for at least 5 hours with no losses, and could be rapidly ejected from the SLIM trap.
- Authors:
-
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Biological Sciences Division
- Publication Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States). Environmental Molecular Sciences Laboratory (EMSL)
- Sponsoring Org.:
- USDOE Office of Science (SC), Biological and Environmental Research (BER); USDOE Laboratory Directed Research and Development (LDRD) Program
- OSTI Identifier:
- 1208779
- Report Number(s):
- PNNL-SA-107651
Journal ID: ISSN 0003-2700; 48680; 48135; KP1601010
- Grant/Contract Number:
- AC05-76RL01830
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Analytical Chemistry
- Additional Journal Information:
- Journal Volume: 87; Journal Issue: 12; Journal ID: ISSN 0003-2700
- Publisher:
- American Chemical Society (ACS)
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS; lossless ion trapping; high pressure; SLIM; ion manipulation; ion storage; ion accumulation; ion release; Environmental Molecular Sciences Laboratory
Citation Formats
Zhang, Xinyu, Garimella, Sandilya V. B., Prost, Spencer A., Webb, Ian K., Chen, Tsung-Chi, Tang, Keqi, Tolmachev, Aleksey V., Norheim, Randolph V., Baker, Erin S., Anderson, Gordon A., Ibrahim, Yehia M., and Smith, Richard D. Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations. United States: N. p., 2015.
Web. doi:10.1021/acs.analchem.5b00214.
Zhang, Xinyu, Garimella, Sandilya V. B., Prost, Spencer A., Webb, Ian K., Chen, Tsung-Chi, Tang, Keqi, Tolmachev, Aleksey V., Norheim, Randolph V., Baker, Erin S., Anderson, Gordon A., Ibrahim, Yehia M., & Smith, Richard D. Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations. United States. https://doi.org/10.1021/acs.analchem.5b00214
Zhang, Xinyu, Garimella, Sandilya V. B., Prost, Spencer A., Webb, Ian K., Chen, Tsung-Chi, Tang, Keqi, Tolmachev, Aleksey V., Norheim, Randolph V., Baker, Erin S., Anderson, Gordon A., Ibrahim, Yehia M., and Smith, Richard D. Sun .
"Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations". United States. https://doi.org/10.1021/acs.analchem.5b00214. https://www.osti.gov/servlets/purl/1208779.
@article{osti_1208779,
title = {Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations},
author = {Zhang, Xinyu and Garimella, Sandilya V. B. and Prost, Spencer A. and Webb, Ian K. and Chen, Tsung-Chi and Tang, Keqi and Tolmachev, Aleksey V. and Norheim, Randolph V. and Baker, Erin S. and Anderson, Gordon A. and Ibrahim, Yehia M. and Smith, Richard D.},
abstractNote = {Here, a structure for lossless ion manipulation (SLIM) module was constructed with electrode arrays patterned on a pair of parallel printed circuit boards (PCB) separated by 5 mm and utilized to investigate capabilities for ion trapping at 4 Torr. Positive ions were confined by application of RF having alternating phases on a series of inner rung electrodes and by positive DC potentials on surrounding guard electrodes on each PCB. An axial DC field was also introduced by stepwise varying the DC potential of the inner rung electrodes so as to control the ion transport and accumulation inside the ion trap. We show that ions could be trapped and accumulated with 100% efficiency, stored for at least 5 hours with no losses, and could be rapidly ejected from the SLIM trap.},
doi = {10.1021/acs.analchem.5b00214},
journal = {Analytical Chemistry},
number = 12,
volume = 87,
place = {United States},
year = {Sun Jun 14 00:00:00 EDT 2015},
month = {Sun Jun 14 00:00:00 EDT 2015}
}
Web of Science
Works referenced in this record:
Geonium theory: Physics of a single electron or ion in a Penning trap
journal, January 1986
- Brown, Lowell S.; Gabrielse, Gerald
- Reviews of Modern Physics, Vol. 58, Issue 1
Gas-phase kinetics and catalytic reactions of small silver and gold clusters
journal, May 2005
- Bernhardt, Thorsten M.
- International Journal of Mass Spectrometry, Vol. 243, Issue 1
Electromagnetic traps for charged and neutral particles
journal, July 1990
- Paul, Wolfgang
- Reviews of Modern Physics, Vol. 62, Issue 3
Studies of Clusters and Biomolecules in ELISA
journal, January 2003
- Andersen, J. U.; Andersen, L. H.; Hvelplund, P.
- Hyperfine Interactions, Vol. 146/147, Issue 1-4
Size-Dependent Electron-Impact Detachment of Internally Cold and Clusters
journal, August 2004
- Diner, A.; Toker, Y.; Strasser, D.
- Physical Review Letters, Vol. 93, Issue 6
Conetrap: A compact electrostatic ion trap
journal, February 2001
- Schmidt, Henning T.; Cederquist, Henrik; Jensen, Jens
- Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 173, Issue 4
Lifting of the trapping potential during ion storage for multi-anion production in a Penning trap
journal, March 2012
- Martinez, Franklin; Bandelow, Steffi; Breitenfeldt, Christian
- International Journal of Mass Spectrometry, Vol. 313
Permanent magnet Penning trap for heavy ion storage
journal, August 2002
- Suess, L.; Finch, C. D.; Parthasarathy, R.
- Review of Scientific Instruments, Vol. 73, Issue 8
Accumulation and Storage of Ionized Duplex DNA Molecules in a Quadrupole Ion Trap
journal, October 1994
- Doktycz, Mitchel J.; Habibi-Goudarzi, Sohrab.; McLuckey, Scott A.
- Analytical Chemistry, Vol. 66, Issue 20
Quadrupole ion trap studies of fundamental organic reactions
journal, January 2004
- Gronert, Scott
- Mass Spectrometry Reviews, Vol. 24, Issue 1
Detection of electrospray ionization using a quadrupole ion trap storage/reflectron time-of-flight mass spectrometer
journal, October 1993
- Michael, Steven M.; Chien, Benjamin M.; Lubman, David M.
- Analytical Chemistry, Vol. 65, Issue 19
Development of High-Sensitivity Ion Trap Ion Mobility Spectrometry Time-of-Flight Techniques: A High-Throughput Nano-LC-IMS-TOF Separation of Peptides Arising from a Drosophila Protein Extract
journal, October 2003
- Myung, Sunnie; Lee, Young Jin; Moon, Myeong Hee
- Analytical Chemistry, Vol. 75, Issue 19
Nondestructive Ion Trap Mass Analysis at High Pressure
journal, February 2011
- Xu, Wei; Maas, Jeffrey B.; Boudreau, Frank J.
- Analytical Chemistry, Vol. 83, Issue 3
Ion funnels for the masses: Experiments and simulations with a simplified ion funnel
journal, October 2005
- Julian, Ryan R.; Mabbett, Sarah R.; Jarrold, Martin F.
- Journal of the American Society for Mass Spectrometry, Vol. 16, Issue 10, p. 1708-1712
A novel ion funnel for focusing ions at elevated pressure using electrospray ionization mass spectrometry
journal, October 1997
- Schaffer, Scott A.; Tang, Keqi; Anderson, Gordon A.
- Rapid Communications in Mass Spectrometry, Vol. 11, Issue 16
An Ion Funnel Interface for Improved Ion Focusing and Sensitivity Using Electrospray Ionization Mass Spectrometry
journal, October 1998
- Shaffer, Scott A.; Prior, David C.; Anderson, Gordon A.
- Analytical Chemistry, Vol. 70, Issue 19, p. 4111-4119
Improving mass spectrometer sensitivity using a high-pressure electrodynamic ion funnel interface
journal, September 2006
- Ibrahim, Yehia; Tang, Keqi; Tolmachev, Aleksey V.
- Journal of the American Society for Mass Spectrometry, Vol. 17, Issue 9, p. 1299-1305
Reactions of Gaseous Ions. VIII. Multiple Order Ion-Molecule Reactions and the Ultra-High Pressure Mass Spectrum of Ethylene
journal, April 1961
- Field, F. H.
- Journal of the American Chemical Society, Vol. 83, Issue 7
High‐Pressure Ion–Molecule Reactions in Carbon Monoxide and Carbon Monoxide–Methane Mixtures
journal, February 1971
- Chong, Shuang‐Ling; Franklin, J. L.
- The Journal of Chemical Physics, Vol. 54, Issue 4
High pressure investigations of positive ion/molecule reactions in pure sulfur hexafluoride and in a mixture of sulfur hexafluoride and argon
journal, July 1996
- Bederski, Krzysztof; Wójcik, Leszek
- International Journal of Mass Spectrometry and Ion Processes, Vol. 154, Issue 3
High pressure mass spectrometric study of ion/molecule reactions in the carbon dioxide–methane mixtures
journal, March 2003
- Wójcik, Leszek; Markowski, Artur
- Vacuum, Vol. 70, Issue 2-3
The high-pressure segmented quadrupole collision cell (HP-SQCC) as an ion molecule reactor
journal, June 2005
- Guo, Yuzhu; Siu, K. W. Michael; Baranov, Vladimir I.
- Journal of the American Society for Mass Spectrometry, Vol. 16, Issue 6
Isomeric identification and quantification of polycyclic aromatic hydrocarbons in environmental samples by liquid chromatography tandem mass spectrometry using a high pressure quadrupole collision cell
journal, June 1998
- Mansoori, Bashir A.
- Rapid Communications in Mass Spectrometry, Vol. 12, Issue 11
Analytical performance of a high-pressure radio frequency-only quadrupole collision cell with an axial field applied by using conical rods
journal, August 1998
- Mansoori, Bashir A.; Dyer, Edward W.; Lock, Christopher M.
- Journal of the American Society for Mass Spectrometry, Vol. 9, Issue 8
Development of a new ion mobility time-of-flight mass spectrometer
journal, February 2015
- Ibrahim, Yehia M.; Baker, Erin S.; Danielson, William F.
- International Journal of Mass Spectrometry, Vol. 377
Electrodynamic Containment of Charged Particles
journal, March 1959
- Wuerker, R. F.; Shelton, H.; Langmuir, R. V.
- Journal of Applied Physics, Vol. 30, Issue 3
Exchange-Collision Technique for the rf Spectroscopy of Stored Ions
journal, June 1968
- Major, F. G.; Dehmelt, H. G.
- Physical Review, Vol. 170, Issue 1
Effect of charge exchange reactions on the motion of ions in three-dimensional quadrupole electric fields
journal, November 1976
- Bonner, R. F.; March, R. E.; Durup, J.
- International Journal of Mass Spectrometry and Ion Physics, Vol. 22, Issue 1-2
Recent improvements in and analytical applications of advanced ion trap technology
journal, September 1984
- Stafford, G. C.; Kelley, P. E.; Syka, J. E. P.
- International Journal of Mass Spectrometry and Ion Processes, Vol. 60, Issue 1
Collisional focusing effects in radio frequency quadrupoles
journal, May 1992
- Douglas, D. J.; French, J. B.
- Journal of the American Society for Mass Spectrometry, Vol. 3, Issue 4, p. 398-408
A cooler for intense low-energy ion beams
journal, September 2002
- Varentsov, V. L.; Habs, D.
- Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 490, Issue 1-2
Development of an electrospray approach to deposit complex molecules on plasma modified surfaces
journal, November 2003
- Kitching, K. J.; Lee, H-N.; Elam, W. T.
- Review of Scientific Instruments, Vol. 74, Issue 11, p. 4832-4839
High-Sensitivity Ion Mobility Spectrometry/Mass Spectrometry Using Electrodynamic Ion Funnel Interfaces
journal, May 2005
- Tang, Keqi; Shvartsburg, Alexandre A.; Lee, Hak-No
- Analytical Chemistry, Vol. 77, Issue 10, p. 3330-3339
Ion mobility spectrometry—mass spectrometry performance using electrodynamic ion funnels and elevated drift gas pressures
journal, July 2007
- Baker, Erin Shammel; Clowers, Brian H.; Li, Fumin
- Journal of the American Society for Mass Spectrometry, Vol. 18, Issue 7, p. 1176-1187
Enhanced Ion Utilization Efficiency Using an Electrodynamic Ion Funnel Trap as an Injection Mechanism for Ion Mobility Spectrometry
journal, February 2008
- Clowers, Brian H.; Ibrahim, Yehia M.; Prior, David C.
- Analytical Chemistry, Vol. 80, Issue 3, p. 612-623
Ion Funnel Trap Interface for Orthogonal Time-of-Flight Mass Spectrometry
journal, October 2007
- Ibrahim, Yehia; Belov, Mikhail E.; Tolmachev, Aleksey V.
- Analytical Chemistry, Vol. 79, Issue 20
Automated Gain Control Ion Funnel Trap for Orthogonal Time-of-Flight Mass Spectrometry
journal, July 2008
- Ibrahim, Yehia M.; Belov, Mikhail E.; Liyu, Andrei V.
- Analytical Chemistry, Vol. 80, Issue 14
Experimental Evaluation and Optimization of Structures for Lossless Ion Manipulations for Ion Mobility Spectrometry with Time-of-Flight Mass Spectrometry
journal, September 2014
- Webb, Ian K.; Garimella, Sandilya V. B.; Tolmachev, Aleksey V.
- Analytical Chemistry, Vol. 86, Issue 18, p. 9169-9176
Characterization of Ion Dynamics in Structures for Lossless Ion Manipulations
journal, September 2014
- Tolmachev, Aleksey V.; Webb, Ian K.; Ibrahim, Yehia M.
- Analytical Chemistry, Vol. 86, Issue 18, p. 9162-9168
Simulation of Electric Potentials and Ion Motion in Planar Electrode Structures for Lossless Ion Manipulations (SLIM)
journal, September 2014
- Garimella, Sandilya V. B.; Ibrahim, Yehia M.; Webb, Ian K.
- Journal of The American Society for Mass Spectrometry, Vol. 25, Issue 11, p. 1890-1896
Mobility-Resolved Ion Selection in Uniform Drift Field Ion Mobility Spectrometry/Mass Spectrometry: Dynamic Switching in Structures for Lossless Ion Manipulations
journal, September 2014
- Webb, Ian K.; Garimella, Sandilya V. B.; Tolmachev, Aleksey V.
- Analytical Chemistry, Vol. 86, Issue 19, p. 9632-9637
Experimental investigation of planar ion traps
journal, March 2006
- Pearson, C. E.; Leibrandt, D. R.; Bakr, W. S.
- Physical Review A, Vol. 73, Issue 3
Radial stratification of ions as a function of mass to charge ratio in collisional cooling radio frequency multipoles used as ion guides or ion traps
journal, January 2000
- Tolmachev, Aleksey V.; Udseth, Harold R.; Smith, Richard D.
- Rapid Communications in Mass Spectrometry, Vol. 14, Issue 20
Works referencing / citing this record:
Ultra-high-resolution ion mobility spectrometry—current instrumentation, limitations, and future developments
journal, April 2019
- Kirk, Ansgar T.; Bohnhorst, Alexander; Raddatz, Christian-Robert
- Analytical and Bioanalytical Chemistry, Vol. 411, Issue 24
Recent technical advances in proteomics
journal, January 2019
- Yates, III, John R.
- F1000Research, Vol. 8
Advances in targeted proteomics and applications to biomedical research
journal, August 2016
- Shi, Tujin; Song, Ehwang; Nie, Song
- PROTEOMICS, Vol. 16, Issue 15-16
Nanowell-mediated multidimensional separations combining nanoLC with SLIM IM-MS for rapid, high-peak-capacity proteomic analyses
journal, November 2018
- Dou, Maowei; Chouinard, Christopher D.; Zhu, Ying
- Analytical and Bioanalytical Chemistry, Vol. 411, Issue 21
Profiling microbial lignocellulose degradation and utilization by emergent omics technologies
journal, July 2016
- Rosnow, Joshua J.; Anderson, Lindsey N.; Nair, Reji N.
- Critical Reviews in Biotechnology, Vol. 37, Issue 5
Recent technical advances in proteomics
journal, January 2019
- Yates, III, John R.
- F1000Research, Vol. 8