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Title: Development of a Process for the Spinning of Synthetic Spider Silk

Spider silks have unique mechanical properties but current efforts to duplicate those properties with recombinant proteins have been unsuccessful. Here, this study was designed to develop a single process to spin fibers with excellent and consistent mechanical properties. As-spun fibers produced were brittle, but by stretching the fibers the mechanical properties were greatly improved. A water-dip or water-stretch further increased the strength and elongation of the synthetic spider silk fibers. Given the promising results of the water stretch, a mechanical double-stretch system was developed. Both a methanol/water mixture and an isopropanol/water mixture were independently used to stretch the fibers with this system. We found that the methanol mixture produced fibers with high tensile strength while the isopropanol mixture produced fibers with high elongation.
 [1] ;  [1] ;  [1] ;  [1]
  1. Utah State Univ., Logan, UT (United States). Dept. of Biological Engineering and Synthetic Biomanufacturing Center
Publication Date:
Accepted Manuscript
Journal Name:
ACS Biomaterials Science & Engineering
Additional Journal Information:
Journal Volume: 1; Journal Issue: 7; Journal ID: ISSN 2373-9878
American Chemical Society (ACS)
Research Org:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org:
USDOE Office of Science (SC); National Science Foundation (NSF)
Country of Publication:
United States
36 MATERIALS SCIENCE; 59 BASIC BIOLOGICAL SCIENCES; spider silk; spinning; mechanical properties; XRD; process development
OSTI Identifier: