Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer
Abstract
Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry provides unparalleled mass accuracy and resolving power.[1],[2] With electrospray ionization (ESI), ions are typically transferred into the mass spectrometer through a skimmer, which serves as a conductance-limiting orifice. However, the skimmer allows only a small fraction of incoming ions to enter the mass spectrometer. An ion funnel, originally developed by Smith and coworkers at Pacific Northwest National Laboratory (PNNL)[3-5] provides much more efficient ion focusing and transfer. The large entrance aperture of the ion funnel allows almost all ions emanating from a heated capillary to be efficiently captured and transferred, resulting in nearly lossless transmission.
- Authors:
-
- Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab. (MagLab), Ion Cyclotron Resonance Program
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
- Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry
- Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab. (MagLab), Ion Cyclotron Resonance Program; Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry
- Publication Date:
- Research Org.:
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)
- Sponsoring Org.:
- USDOE; National Science Foundation (NSF)
- OSTI Identifier:
- 1188871
- Report Number(s):
- PNNL-SA-104452
Journal ID: ISSN 1076-5174; 48135; 47418; KP1601010
- Grant/Contract Number:
- AC05-76RL01830; CHE-1019193; DMR-11-57490; P41 GM103493
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Journal of Mass Spectrometry
- Additional Journal Information:
- Journal Volume: 50; Journal Issue: 1; Journal ID: ISSN 1076-5174
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION; 42 ENGINEERING; FT MS; ICR; quadrupole ion guide; ion funnel; mass selection; Environmental Molecular Sciences Laboratory
Citation Formats
Chen, Yu, Leach, Franklin E., Kaiser, Nathan K., Dang, Xibei, Ibrahim, Yehia M., Norheim, Randolph V., Anderson, Gordon A., Smith, Richard D., and Marshall, Alan G. Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer. United States: N. p., 2015.
Web. doi:10.1002/jms.3523.
Chen, Yu, Leach, Franklin E., Kaiser, Nathan K., Dang, Xibei, Ibrahim, Yehia M., Norheim, Randolph V., Anderson, Gordon A., Smith, Richard D., & Marshall, Alan G. Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer. United States. https://doi.org/10.1002/jms.3523
Chen, Yu, Leach, Franklin E., Kaiser, Nathan K., Dang, Xibei, Ibrahim, Yehia M., Norheim, Randolph V., Anderson, Gordon A., Smith, Richard D., and Marshall, Alan G. Mon .
"Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer". United States. https://doi.org/10.1002/jms.3523. https://www.osti.gov/servlets/purl/1188871.
@article{osti_1188871,
title = {Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer},
author = {Chen, Yu and Leach, Franklin E. and Kaiser, Nathan K. and Dang, Xibei and Ibrahim, Yehia M. and Norheim, Randolph V. and Anderson, Gordon A. and Smith, Richard D. and Marshall, Alan G.},
abstractNote = {Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry provides unparalleled mass accuracy and resolving power.[1],[2] With electrospray ionization (ESI), ions are typically transferred into the mass spectrometer through a skimmer, which serves as a conductance-limiting orifice. However, the skimmer allows only a small fraction of incoming ions to enter the mass spectrometer. An ion funnel, originally developed by Smith and coworkers at Pacific Northwest National Laboratory (PNNL)[3-5] provides much more efficient ion focusing and transfer. The large entrance aperture of the ion funnel allows almost all ions emanating from a heated capillary to be efficiently captured and transferred, resulting in nearly lossless transmission.},
doi = {10.1002/jms.3523},
journal = {Journal of Mass Spectrometry},
number = 1,
volume = 50,
place = {United States},
year = {Mon Jan 19 00:00:00 EST 2015},
month = {Mon Jan 19 00:00:00 EST 2015}
}
Web of Science
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Works referencing / citing this record:
Characterisation and optimisation of ion discrimination in a mini ion funnel for a miniature mass spectrometer
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