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Title: Rational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine Detoxification

Authors:
 [1] ;  [2] ;  [1] ;  [1] ;  [1] ;  [2] ;  [1] ;  [1]
  1. Molecular Modeling and Biopharmaceutical Center and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky 40536, United States
  2. Department of Molecular and Cellular Biochemistry and Center for Structural Biology, University of Kentucky, 741 South Limestone Street, Lexington, Kentucky 40536, United States
Publication Date:
Grant/Contract Number:
W-31-109-Eng-38
Type:
Published Article
Journal Name:
ACS Chemical Biology
Additional Journal Information:
Journal Name: ACS Chemical Biology Journal Volume: 9 Journal Issue: 8; Journal ID: ISSN 1554-8929
Publisher:
American Chemical Society
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
OSTI Identifier:
1158719

Fang, Lei, Chow, K. Martin, Hou, Shurong, Xue, Liu, Chen, Xiabin, Rodgers, David W., Zheng, Fang, and Zhan, Chang-Guo. Rational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine Detoxification. United States: N. p., Web. doi:10.1021/cb500257s.
Fang, Lei, Chow, K. Martin, Hou, Shurong, Xue, Liu, Chen, Xiabin, Rodgers, David W., Zheng, Fang, & Zhan, Chang-Guo. Rational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine Detoxification. United States. doi:10.1021/cb500257s.
Fang, Lei, Chow, K. Martin, Hou, Shurong, Xue, Liu, Chen, Xiabin, Rodgers, David W., Zheng, Fang, and Zhan, Chang-Guo. 2014. "Rational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine Detoxification". United States. doi:10.1021/cb500257s.
@article{osti_1158719,
title = {Rational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine Detoxification},
author = {Fang, Lei and Chow, K. Martin and Hou, Shurong and Xue, Liu and Chen, Xiabin and Rodgers, David W. and Zheng, Fang and Zhan, Chang-Guo},
abstractNote = {},
doi = {10.1021/cb500257s},
journal = {ACS Chemical Biology},
number = 8,
volume = 9,
place = {United States},
year = {2014},
month = {6}
}