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Title: Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy

Authors:
 [1] ;  [1] ;  [1] ;  [2] ;  [1] ;  [1] ;  [1] ;  [1] ;  [3] ;  [1] ;  [1] ;  [1] ;  [1] ;  [4] ;  [4] ;  [5] ;  [2] ;  [4] ;  [1]
  1. Department of Entomology and Nematology, UCD Comprehensive Cancer Center, University of California Davis, One Shields Avenue, Davis, California 95616, United States
  2. Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, United States
  3. Department of Entomology and Nematology, UCD Comprehensive Cancer Center, University of California Davis, One Shields Avenue, Davis, California 95616, United States, Department of Applied Chemistry, China Agricultural University, Beijing 100193, People’s Republic of China
  4. Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States
  5. Department of Pharmacology, University of California Davis, Davis, California 95616, United States
Publication Date:
Type:
Published Article
Journal Name:
Journal of Medicinal Chemistry
Additional Journal Information:
Journal Volume: 57; Journal Issue: 16; Related Information: CHORUS Timestamp: 2017-11-09 11:18:55; Journal ID: ISSN 0022-2623
Publisher:
American Chemical Society
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
OSTI Identifier:
1150841