Document Details
PURL
Title:
IRRADIATION OF THE GASTROINTESTINAL TRACT OF THE RAT BY INGESTED RUTHENIUM-106
Author(s):
Subject Terms:
MINERAL METABOLISMRadiation and Radiation ProtectionRadiobiologyRATES - MINERAL UPTAKERUTHENIUM ISOTOPES RU-106
Document Location:
DOE Public Reading Room - Hanford Battelle P.O. Box 999 MS H2-53 Richland WA 99352 (509)372-7443
Document Type:
REPORT
Publication Date:
1956 Oct 01
Declassification Status:
Declassified
Document Pages:
32
Accession Number:
RL-1-364450
Document Number(s):
HW-45546
Originating Research Org.:
GE - HAPO
OpenNet Entry Date:
2004 Feb 24
OpenNet Modified Date:
2015 Aug 24
Description/Abstract:
RATS WERE SACRIFICED AT INTERVALS FROM 35 MINUTES TO 30 HOURS FOLLOWING INTRAGASTRIC ADMINISTRATION OF A SOLUTION OF RU-106 CHLORIDE. DISTRIBUTION OF RU-106 WITHING THE VARIOUS SEGMENTS OF THE GASTROINTESTINAL TRACT, AND DISTRIBUTION OF TRACT CONTENTS WERE DETD. ANALAYSIS WERE ALSO MADE FOR ABSORBED RU-106 IN BLOOD AND KIDNEYS. LARGES DOSE IS DELIVERED TO THE LOWER LARGE INTESTINE. SIGNIFICATN ABSORPTION FROM THE GASTROINTENSITINAL TRACT OCCURS DURING NOT MORE THAN THE FIRST 35 MINUTES FOLLOWING INTRAGSTRIC ADMINISTRATION. RU IS RAPIDLY CLEARED FROM THE BLOOD. MAX CONCN OF RU IN THE KIDNEY COMES WITHIN 3 HOURS AFTER FEEDING, AND IS LOST WITH A HALF LIFE OF ABOUT 1 DAY.