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Title:
INJURY DUE TO ACCIDENTAL HIGH-DOSE EXPOSURE TO 10 MEV ELECTRONS ( HEALTH PHYSICS, VOL. 13, PP 241-251, 1967 )
Author(s):
LANZEL, L H [ARGONNE CANCER RESEARCH HOSPITAL]; ROZENFELD, M L [ARGONNE CANCER RESEARCH HOSPITAL]; TARLOV, A R [ARGONNE CANCER RESEARCH HOSPITAL]
Subject Terms:
HREX
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1966 Mar 31
Declassification Status:
Never classified
Document Pages:
0016
Accession Number:
NV0704445
Originating Research Org.:
HAZELTON LABS, INCORPORATED
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2012 May 14
Description/Abstract:
AN INDUSTRIAL WORKER WAS ACCIDENTALLY EXPOSED TO A 10-MEV ELECTRON BEAM FROM A LINEAR ACCELERATOR. DOSIMETRIC INFORMATION WAS ASSEMBLED IMMEDIATELY AFTER THE EVENT, AND LATER, THROUGH A RECONSTRUCTION OF THE ACCIDENT. THE DOSE GRADIENT ABOUT THE PRIMARY ELECTRON BEAM WAS HIGH, GIVING ESTIMATED DOSES TO VARIOUS PARTS OF THE RIGHT HAND WHICH RANGED FROM 40,000 TO 240,000 RAD. THE INTERIOR OF THE BODY RECEIVED DOSES RANGING FROM 0.2 TO 5 RAD. THESE MEASUREMENTS OF THE INTERNAL DOSE WERE CONSISTENT WITH ESTIMATES MADE IMMEDIATELY AFTER THE ACCIDENT BASED ON THE VICTIM'S FILM BADGE READING AND CALCULATIONS OF BREMSSTRAHLUNG FORMATION IN THE SKIN OF THE CHEST FROM A HIGHLY SCATTERED ELECTRON BEAM. THIS EARLY ESTIMATE HAD PROVIDED GREAT CONFIDENCE THAT THE INJURED WOULD SURVIVE, SINCE THE BLOOD-FORMING TISSUES WOULD NOT HAVE BEEN IMPAIRED BY THESE DOSAGES. CLINICAL OBSERVATIONS PERTAINING TO THE DEVELOPMENT OF SKIN CHANGES AND LOSS OF NEUROLOGIC FUNCTION IN THE HAND AND LEG LED TO MUCH LOWER ESTIMATES OF THE DOSAGE RECEIVED BY THESE EXTREMITIES THAN THE PHYSICAL DOSIMETRY LATER PROVIDED. THIS CASE ILLUSTRATES THAT THE ULTIMATE EXTENT TO TISSUE INJURY AND NECROSIS CAN BE AS YET ANTICIPATED FROM EARLY CLINICAL OBSERVATION. THE LATE, OR DELAYED, EFFECTS OF IRRADIATION EVENTUATED IN DOUBLE AMPUTATION 5-6 MONTHS AFTER EXPOSURE. EXPERIMENTAL DATA PRIMATES IS BADLY NEEDED TO PROVIDE A FOUNDATION FOR PROGNOSIS AND A GUIDE TO THERAPY OF INJURED HUMANS.