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Title:

POSTNATAL HISOGENESIS AND ENDOCINE FUNCTION OF ABNORMAL TESTES IN THE AXC RAT (24105) ( PROCEEDINGS OF SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1958, V98, PP 553-557 )

Author(s):

HERTZ, R [NATIONAL INSTITUTE OF HEALTH]; VILAR, O [NATIONAL INSTITUTE OF HEALTH]

Subject Terms:

HREX

Document Location:

Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV

Document Type:

JOURNAL ARTICLE

Publication Date:

1958 Dec 31

Declassification Status:

Never classified

Document Pages:

0005

Accession Number:

NV0703819

OpenNet Entry Date:

1994 Aug 27

OpenNet Modified Date:

2012 May 14

Description/Abstract:

IN THE AXC MALE RAT THE ANOMALOUS PATTERN INCLUDES A TOTAL ABSENCE OF KIDNEY AND URETER ON ONE SIDE FREQUENTLY ASSOCIATED WITH PRESENCE ON THE SAME SIDE OF AN ATROPHIC TESTIS WHICH LACKS A VAS DEFERENS OR EPIDIDYMIS. THE PURPOSE IS TO REPORT OBSERVATIONS ON POSTNATAL DEVELOPMENT OF THE ABNORMAL TESTIS IN THE AXC RAT. ALL ANIMALS WERE SACRIFICED BY ETHER AT INDICATED AGE. TESTES WHICH COULD BE EXPECTED TO BE ATROPHIC WERE IDENTIFIED BY OCCURRENCE ON THE SAME SIDE AS THE OBSERVED ABSENCE OF VAS DEFERENS, KIDNEY, URETER AND SEMINAL VESICLE. DETAILED HISTOCHEMICAL AND HISTOLOGICAL ANALYSIS OF THE POSTNATAL DEVELOPMENT OF THE DEFECTIVE TESTIS REVEALS THAT THIS TESTIS CAN NOT BE DIFFERENTIATED FROM THE NORMAL TESTIS UNTIL PUBERTY.

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