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OUTLINE OF PRESENTATION RE PLUTONIUM PATIENTS ( PLUTONIUM INJECTION EXPERIMENT )

HREX; AGREEMENT; EXCRETION; INJECTIONS; OUTLINE; PATIENTS; PLUTONIUM; PRESENTATION; STUDIES

Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV

BOOK

Never classified

0002

NV0703545

1994 Aug 27

2012 May 14

PLUTONIUM INJECTED PATIENTS - OUTLINE - THE REASONS FOR INJECTIONS AND STUDIES EARLIER IS THAT EXCRETION DATA IS NEEDED FOR HUMAN BURDEN. ESTIMATION AND AN UNEASINESS OVER USE OF ANIMAL DATA FOR HUMANS EXISTED. THE RECENT STUDIES SHOW COMPLETION OF EXCRETION CURVES AND A LATE DISTRIBUTION OF PU IN EXHUMED HUMAN BONES. A WRITTEN CONSENT FOR PATIENTS WAS RARE IN 1945. IN SOME REPORTED CASES (CHICAGO) A WITNESS CLAIMED THAT ORAL CONSENT WAS OBTAINED BY A PHYSICIAN. THE NAMED PHYSICIAN DENIED INVOLVEMENT. IN OAK RIDGE THERE WAS NO DISCLOSURE MADE TO ONE OAK RIDGE PATIENT. IN ROCHESTER, THERE WAS NO RECORD OF DISCLOSURE TO 11 PATIENTS. DR. BASSETT, IN CHARGE OF THE WARD, IS DECEASED. SAN FRANCISCO - THERE IS NO RECORD OF DISCLOSURE TO TWO PU AND ONE AM PATIENT. NAMED PHYSICIAN DID NOT RECALL CASES. THE THIRD CAL CASE IN JULY 1947 HAD GOOD DISCLOSURE ON HOSPITAL CHART WITH WITNESS SIGNATURES. THE LATE STUDIES SHOW CHR NOT KNOWLEDGEABLE RE EARLY DISCLOSURE. THE CHR CONTACT WITH CAL-3 MADE UNDER PRETENSE OF FOLLOW-UP OF EARLIER THERAPY. A CONSENT FORM WAS NOT USED FOR CAL-3. A 1973 CHR STUDY REFERRED TO HUMAN USE COMMITTEE IN NOVEMBER 1973 WELL AFTER THE STUDY WAS BEGUN. ON APRIL 8, 1974, THE COMMITTEE ADVISED ON STEPS TO COMPLY WITH GUIDELINES.