Document Details
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Title:
RADIOACTIVE IODIDE UPTAKE OF NORMAL NEWBORN INFANTS ( A.M.A. AMERICAN JOURNAL OF DISEASES OF CHILDREN, OCT 1954, VOL. 88, PP 439-442 )
Author(s):
Subject Terms:
HREX; CHILDREN; INFANTS; IODINE; UPTAKE
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1954 Oct 31
Declassification Status:
Never classified
Document Pages:
0005
Accession Number:
NV0703500
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2012 May 14
Description/Abstract:
THYROID FUNCTION OF THE NEWBORN WAS STUDIED BY DANOWSKI AND CO-WORKERS AND BY MAN AND CO-WORKERS, WHO DETERMINED THE PLASMA LEVEL OF THE THYROXINE-LIKE PROTEIN-BOUND IODINE AND BUTANOL-EXTRACTABLE IODIDE. IN INFANTS 1 TO 3 DAYS OLD, PROTEIN-BOUND IODINE AVERAGED 12.0 GAMMA PER 100 CUBIC CENTIMETERS, AND BUTANOL-EXTRACTABLE IODINE IN INFANTS OF 2 TO 6 DAYS WAS 7.0 TO 11.7 GAMMA PER 100 CUBIC CENTIMETERS. THESE RESULTS ARE COMPATIBLE WITH HYPERTHYROIDISM IN ADULTS OR OLDER CHILDREN. SEVERAL REPORTS INDICATED THAT IODINE-131 UPTAKES BY THE THYROIDS OF NORMAL CHILDREN "LESS THAN 1 YEAR" TO 14 YEARS OF AGE WERE WELL WITHIN THE BROAD RANGE OF NORMAL ADULTS. APPARENTLY, NO IODINE- 131 STUDIES HAVE BEEN REPORTED ON NEWBORN INFANTS. THE ABSENCE OF SUCH STUDIES RESULTS PARTLY FROM THE PREVIOUS LACK OF SATISFACTORY INSTRUMENTS FOR ACCURATE DETECTION OF SAFE DOSES.