PURL
(820 K)
Title:
THE BIOLOGIC DECAY PERIOD OF SODIUM IN NORMAL MAN, IN PATIENTS WITH CONGESTIVE HEART FAILURE, & IN PATIENTS WITH THE NEPHROTIC SYNDROME AS DETERMINED BY SODIUM-22 AS THE TRACER( CONT'D IN ABSTRACT )
Subject Terms:
HREX; SODIUM
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1949 Dec 31
Declassification Status:
Never classified
Accession Number:
NV0702754
Originating Research Org.:
REYNOLDS ELECTRICAL AND ENGINEERING COMPANY
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2012 May 14
Description/Abstract:
(CONT'D FROM TITLE) (JOURNAL OF LABORATORY AND CLINICAL MEDICINE, VOL. 34, 1949, PGS 1-13) (PARTIAL). FAILURE OR FROM CHRONIC GLOMERULONEPHRITIS OF THE NEPHROTIC TYPE. BECAUSE OF THE NATURE OF THE EXPERIMENTS, THE TRUE BIOLOGIC HALF-LIFE PERIOD WAS NOT MEASURED DIRECTLY. INSTEAD, THE TIME NECESSARY TO REDUCE THE SERUM CONCENTRATION TO ONE-HALF THE INITIAL LEVEL AFTER THE ESTABLISHMENT OF EQUILIBRIUM AND THE TIME REQUIRED TO ELIMINATE ONE- HALF THE INJECTED SODIUM-22 IN THE URINE WERE DETERMINED. THE IMPORTANCE OF THESE OBSERVATIONS AND THE RELATIVE GENERAL SIGNIFICANCE OF THESE TIME PERIODS IN THE BIOLOGIC APPLICATION OF RADIOELEMENTS, PARTICULARLY RADIOSODIUM, ARE DISCUSSED.