Document Details
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(279 K)
Title:
RELATIONSHIP OF WEIGHT, VENOUS PRESSURE AND RADIOSTRONTIUM ( SODIUM-22 ) EXTREATION IN CHRONIC HEART FAILURE ( CONTINUED IN ABSTRACT )
Author(s):
Subject Terms:
HREX; SODIUM 22; STRONTIUM
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1947 Dec 31
Declassification Status:
Never classified
Document Pages:
0004
Accession Number:
NV0702747
Originating Research Org.:
REYNOLDS ELECTRICAL AND ENGINEERING COMPANY
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2012 May 14
Description/Abstract:
(CONT'D FROM TITLE) (PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, VOL. 66, 1947, PGS. 369-372) (PARTIAL). RELATIONSHIP OF WEIGHT, VENOUS PRESSURE AND SODIUM EXCRETION WAS OBSERVED. EACH SUBJECT RECEIVED AN INTRAVENOUS INJECTION OF A TRACER DOSE OF SODIUM-22. OVER A 2-MONTH PERIOD, ALL URINE SAMPLES WERE COLLECTED SEPARATELY AND THE CONCENTRATION OF RADIOSODIUM DETERMINED FOR EACH, AS WELL AS FOR DAILY SAMPLES OF BLOOD SERUM. THE FINDINGS IN THIS STUDY WERE IN ACCORD WITH THE GENERALLY ACCEPTED IDEAS OF CONGESTIVE HEART FAILURE, THAT IS, THE PATIENTS WITH CONGESTIVE HEART FAILURE WERE FOUND TO EXCRETE LESS THAN NORMAL AMOUNTS OF SODIUM AND WATER DURING THE PERIOD THAT THE FAILURE WAS ADVANCING, BUT DURING THE PERIOD OF IMPROVEMENT THE EXCRETION OF SALT AND WATER EXCEEDED THAT OBSERVED IN THE NORMAL SUBJECT. THE ACTUAL MECHANISMS OF THE RETENTION OF SODIUM AND WATER IN CONGESTIVE HEART FAILURE REMAIN UNKNOWN.