Document Details
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(288 K)
Title:
REGRESSION OF A RADIOACTIVE MERCURIAL DIURETIC FROM THE PLASMA OF MAN ( LETTER TO THE EDITOR ) ( NATURE, VOL. 163, APRIL 23, 1949, PGS. 640-641 ) (PARTIAL)
Author(s):
BURCH, G E [TULANE UNIVERSITY]; CRONVICH, J A; GORDON, W H; MILNOR, J P; OVERMAN, W J; RAY, C T; REASER, P B; THREEFOOT, S A
Subject Terms:
HREX; MERCURY
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1949 Apr 23
Declassification Status:
Never classified
Document Pages:
0003
Accession Number:
NV0702744
Originating Research Org.:
REYNOLDS ELECTRICAL AND ENGINEERING COMPANY
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2012 May 14
Description/Abstract:
INVESTIGATIONS HAVE BEEN CARRIED OUT WITH THE USE OF RADIOACTIVE MERCURY INCORPORATED IN A MERCURIAL DIURETIC, 'MERCUHYDRIN', IN ORDER TO OBSERVE FOR A PERIOD OF 100-180 MINUTES THE CONCENTRATION-TIME COURSE OF THE ISOTOPE IN THE PLASMA OF MAN AFTER INTRAVENOUS INJECTION. FIFTEEN SUBJECTS WERE STUDIED. LABELLED MERCURIAL DIURETIC WAS INJECTED INTO THE ANTECUBITAL VEIN OF ONE ARM OF THE SUBJECTS OVER A PERIOD OF ABOUT 20 SECONDS, AND BLOOD SAMPLES WERE DRAWN RAPIDLY FROM THE ANTECUBITAL VEIN OF THE CONTRALATERAL SIDE. THE ANALYSIS OF THE REGRESSION OF MERCURY FROM THE PLASMA OF MAN IS UNDOUBTEDLY AN OVER-SIMPLIFICATION OF MULTIPLE COMPLEX PHENOMENA BUT IT SERVES AS A BASIS FOR AN UNDERSTANDING OF OTHER DATA DEPENDENT UPON THE CONCENTRATION OF MERCURY IN THE PLASMA.