Document Details
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Title:
THEORETIC & EXPERIMENTAL CONSIDERATIONS OF BIOLOGIC DECAY PERIODS: STUDIES IN MAN WITH THE USE OF SODIUM-22 ( COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, VOL. 13, 1948, PG. 63-74 ) (PARTIAL
Author(s):
BURCH, G E [TULANE UNIVERSITY]; CRONVICH, J A [TULANE UNIVERSITY]; REASER, P; THREEFOOT, S A [TULANE UNIVERSITY]
Subject Terms:
HREX; SODIUM 22
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1948 Dec 31
Declassification Status:
Never classified
Document Pages:
0013
Accession Number:
NV0702739
Originating Research Org.:
REYNOLDS ELECTRICAL AND ENGINEERING COMPANY
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2012 May 14
Description/Abstract:
( CONT MAN AND IN SUBJECTS WITH CHRONIC CONGESTIVE HEART FAILURE OR WITH THE NEPHROTIC SYNDROME OF CHRONIC GLOMERULONEPHRITIS. CLINICAL PHASES OF THE DISEASES VARIED IN THESE PATIENTS. THE NATURE OF THE EXPERIMENTS MADE IT POSSIBLE TO DETERMINE DIRECTLY THE TRUE BIOLOGIC HALF-LIFE PERIOD FOR SODIUM. IT WAS NECESSARY TO INTRODUCE NEW TERMS FOR BIOLOGIC DECAY PERIODS, SUCH AS THE TIME REQUIRED FOR THE TRACER TO REACH ONE-HALF THE INITIAL CONCENTRATION IN THE COMPARTMENT UNDER STUDY, THE TIME REQUIRED TO ELIMINATE ONE-HALF OF THE TRACER MATERIAL BY WAY OF THE URINE, AND THE TIME REQUIRED TO ELIMINATE ONE-HALF OF THE TRACER SUBSTANCE ADMINISTERED. ALTHOUGH THE PRESENT INVESTIGATIONS WERE CHIEFLY CONCERNED WITH SODIUM, THE THEORETIC CONSIDERATIONS ARE APPLICABLE TO ANY TYPE OF TRACER, ORGANISM, OR COMPARTMENT. THE MATHEMATICAL DATA MAY PROVE TO BE OF VALUE TO OTHERS INTERESTED IN THIS FIELD OF BIOLOGIC RESEARCH.