Document Details
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(869 K)
Title:
THE BIOLOGIC DECAY PERIODS OF SODIUM IN NORMAL MAN, IN PATIENTS WITH CONGESTIVE HEART FAILURE, AND IN PATIENTS WITH THE NEPHROTIC SYNDROME AS DETERMINED BY SODIUM AS THE TRACER( CONT'D IN ABSTRACT )
Author(s):
Subject Terms:
HREX
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1949 Jan 31
Declassification Status:
Never classified
Document Pages:
0013
Accession Number:
NV0702729
Originating Research Org.:
REYNOLDS ELECTRICAL AND ENGINEERING COMPANY
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2012 May 14
Description/Abstract:
(CONT'D FROM TITLE) (JOURNAL OF LABORATORY AND CLINICAL MEDICINE, VOL. 34, NO. 1, JANUARY 1949, PGS. 1-13). FAILURE OR FROM CHRONIC GLOMERULONEPHRITIS OF THE NEPHROTIC TYPE. BECAUSE OF THE NATURE OF THE EXPERIMENTS, THE TRUE BIOLOGIC HALF-LIFE PERIOD WAS NOT MEASURED DIRECTLY. INSTEAD, THE TIME NECESSARY TO REDUCE THE SERUM CONCENTRATION TO ONE-HALF THE INITIAL LEVEL AFTER THE ESTABLISHMENT OF EQUILIBRIUM, AND THE TIME REQUIRED TO ELIMINATE ONE- HALF THE INJECTED SODIUM-22 IN THE URINE WERE DETERMINED. THE IMPORTANCE OF THESE OBSERVATIONS AND THE RELATIVE GENERAL SIGNIFICANCE OF THESE TIME PERIODS IN THE BIOLOGIC APPLICATION OF RADIOELEMENTS, PARTICULARLY RADIOSODIUM, ARE DISCUSSED.