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Title:
THE PATHOLOGICAL PHYSIOLOGY OF RADIATION INJURY IN THE MAMMAL. I. PHYSICAL AND BIOLOGICAL FACTORS IN RADIATION ACTION ( CHAPTER 14 ) (PARTIAL)
Author(s):
BRUES, A M [ARGONNE NATIONAL LABORATORY]; PATT, H M [ARGONNE NATIONAL LABORATORY]
Subject Terms:
HREX
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
Declassification Status:
Never classified
Document Pages:
0021
Accession Number:
NV0702389
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2012 May 14
Description/Abstract:
THE PHYSICAL AND BIOLOGICAL FACTORS AFFECTING SENSITIVITY TO IONIZING RADIATIONS ARE DISCUSSED WITH EMPHASIS DIRECTED TOWARD THE RESPONSE OF MAMMALIAN TISSUE. IT IS SHOWN THAT THE BIOLOGICAL EFFECT MAY BE INFLUENCED BY THE QUALITY, QUANTITY, MANNER, AND COMPLETENESS OF IRRADIATION. IN VIEW OF THE COMPLEXITY OF CELL PHYSIOLOGY AND THE UBIQUITOUS NATURE OF THE ENERGY ABSORPTION, IT IS NOT SURPRISING THAT THE EFFECTS OF RADIATION ARE MANIFESTED IN MANY WAYS AND THAT MANY FACTORS HAVE THE CAPACITY OF INFLUENCING THE RADIATION RESPONSES. THERE IS REASON TO THINK THAT THE CHEMICAL EFFECTS OF IONIZATION AND EXCITATION ARE RESPONSIBLE FOR THE EARLY CYTOLOGICAL DAMAGE FOLLOWING MODERATE DOSAGES OF RADIATION AND THAT THIS, IN TURN, BEARS A CAUSAL RELATION TO THE OVER-ALL INJURY IN THE MAMMALIAN ORGANISM.