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CARCINOMA OF THE EYELID - ANALYSIS OF 301 CASES & REVIEW OF THE LITERATURE ( REPRINTED FROM THE NEW ENGLAND JOURNAL OF MEDICINE 241:725-732, NOV. 10, 1949 )

SCHULTZ, M D [HARVARD UNIVERSITY]; STETSON, C G [HARVARD UNIVERSITY]

HREX

Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV

JOURNAL ARTICLE

Never classified

0013

NV0702373

1994 Aug 27

2017 Dec 21

THE EXPERIENCE WITH TREATMENT OF CARCINOMA OF THE EYELID AT THE MASSACHUSETTS GENERAL HOSPITAL AND AT THE COLLIS P. HUNTINGTON MEMORIAL HOSPITAL DURING THE TWELVE-YEAR PERIOD FROM 1933 THROUGH 1944 IS REVIEWED. THE STUDY WAS BASED ON 301 CASES OF PRIMARY CARCINOMA OF THE EYELID HAVING AN AVERAGE DURATION OF THREE AND A HALF YEARS. HISTOLOGICAL EXAMINATION SHOWED THAT 82 PERCENT OF THE BIOPSIED LESIONS WERE BASAL-CELL CARCINOMAS; 14.5 PERCENT WERE SQUAMOUS-CELL TUMORS. SEVENTY-SIX PERCENT OF PATIENTS RECEIVED IRRADIATION, AND 24 PERCENT WERE TREATED BY SURGICAL PROCEDURES. EVALUATION OF THE RESULTS OF TREATMENT HAS BEEN BASED ON THE GROUP OF CASES IN WHICH THE FOLLOW-UP PERIOD WAS THREE YEARS OR LONGER; PRIMARY FAILURE TO CONTROL THE DISEASE WAS MANIFESTED WITHIN THREE YEARS IN 86 PERCENT OF THE GROUP. APPARENT CURES WERE ULTIMATELY OBTAINED IN 97.5 PERCENT OF THE CASES. FAILURES FROM THE INITIAL TREATMENT, HOWEVER, OCCURRED IN 13 PERCENT; ALL EXCEPT 5 OF THESE 29 LESIONS WERE CONTROLLED BY SUBSEQUENT MANAGEMENT. THE SECONDARY TREATMENT IN MOST CASES WAS NOT THE SAME AS THE PRIMARY HAD BEEN. THE NET FAILURES COMPRISED 2.5 PERCENT OF THE CASES. FROM A PERCENTAGE STANDPOINT THERE WAS NOTHING TO INDICATE THAT THE METHOD OF TREATMENT INFLUENCED THE END-RESULTS. THESE RESULTS HAVE BEEN COMPARED WITH THOSE PREVIOUSLY PUBLISHED BY OTHER WORKERS.