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Title:
FAST NEUTRON RADIOTHERAPY IN THE TREATMENT OF LOCALLY ADVANCED ADENOCCARCINOMA OF THE PROSTATE ( AM J CLIN ONOCOL (CCT) 12(4) )
Author(s):
DAVIS, L W [MONTEFIORE HOSPITAL]; GRIFFIN, T W [UNIVERSITY OF WASHINGTON, SEATTLE]; KRALL, J M [RADIATION THERAPY ONCOLOGY GROUP - PHILADELPHIA, PENNA.]; LARAMORE, G E [UNIVERSITY OF WASHINGTON, SEATTLE]; MAOR, M H; PARKER, R G [UNIVERSITY OF CALIFORNIA]; RUSSELL, K J [UNIVERSITY OF WASHINGTON, SEATTLE]
Subject Terms:
HREX; NEUTRON THERAPY STUDY; STRONTIUM 90
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1989 Dec 31
Declassification Status:
Never classified
Document Pages:
0004
Accession Number:
NV0702224
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2017 Dec 21
Description/Abstract:
THE MAJOR CLINICAL EXPERIENCES USING FAST NEUTRONS FOR THE TREATMENT OF LOCALLY ADVANCED PROSTATIC CARCINOMAS ARE REVIEWED. IN ALL TRIALS TO DATE, THERE IS EVIDENCE THAT TREATMENT REGIMENTS EMPLOYING A COMPONENT OF FAST NEUTRONS ACHIEVE RESULTS THAT EQUAL OR SURPASS THOSE OBTAINABLE WITH CONVENTIONAL MEGAVOLTAGE EXTERNAL BEAM IRRADIATION FOR COMPARABLE GROUPS OF PATIENTS. LATE COMPLICATIONS OF NEUTRON TREATMENT HAVE NOT EXCEEDED THE COMPLICATION RATE EXPECTED BY PHOTON IRRADIATION. THE STRUCTURE OF THE CURRENT RADIATION THERAPY ONCOLOGY GROUP PHASE III RANDOMIZED TRIAL COMPARING NEUTRON AND PHOTON TREATMENT OF PATIENTS WITH STAGES B(2), C, AND D(1) DISEASE IS DISCUSSED.