Document Details
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Title:
EFFECT OF DIETARY ZINC ON THE ABSORPTION OF ORALLY ADMINISTERED ZN 65
Author(s):
FURCHNER, J E [LOS ALAMOS SCIENTIFIC LABORATORY]; RICHMOND, C R [LOS ALAMOS SCIENTIFIC LABORATORY]
Subject Terms:
HREX; ZINC; ZINC 65
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
Declassification Status:
Never classified
Document Pages:
0003
Accession Number:
NV0701354
OpenNet Entry Date:
1994 Aug 27
OpenNet Modified Date:
2017 Dec 21
Description/Abstract:
AN ATTEMPT TO MODIFY THE ABSORPTION OF ORAL 65ZN IN RATS WAS MADE BY THE ADDITION OF NATURAL ZINC ACETATE TO THE DIET OF MALE SPRAGUE- DAWLEY RATS. AFTER THE RATS WERE MAINTAINED ON A ZINC-SUPPLEMENTED DIET FOR 4 WEEKS, AN ORAL DOSE OF 65ZNCL WAS ADMINISTERED TO THE RATS. THE RETENTION OF 65ZN WAS DETERMINED BY WHOLE-BODY ASSAY TECHNIQUES. DIFFERENCES IN PERCENT 65ZN RETAINED WERE ATTRIBUTED TO DIFFERENCES IN THE ZINC ACETATE LEVEL IN THE DIET. DATA FROM 1 HUMAN SUBJECT SUGGEST THAT INTESTINAL ABSORPTION MAY BE DECREASED BY INCREASING DIETARY ZINC LEVELS.