Document Details

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METABOLISM OF INJECTED PLUTONIUM IN TWO HEALTHY MEN

NEWTON, D; TALBOT, R J; WARNER, A J

HREX; HUMANS; METABOLISM; PLUTONIUM; PLUTONIUM INJECTION EXPERIMENT

Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV

JOURNAL ARTICLE

Never classified

0007

NV0701334

1994 Aug 27

2017 Dec 21

THE METABOLISM OF PLUTONIUM HAS BEEN STUDIED FOLLOWING INTRAVENOUS INJECTION OF 237PU AS PU (IV) CITRATE INTO TWO HEALTHY MALE VOLUNTEERS. MEASUREMENTS OF THE TRACER IN SAMPLES OF BLOOD AND EXCRETA WERE MADE BY GAMMA-RAY SPECTROMETRY, AND PATTERNS OF ORGAN UPTAKE WERE INVESTIGATED THROUGH SERIAL MEASUREMENTS WITH A SCINTILLATION COUNTER VIEWING THE LIVER AND SELECTED SKELETAL SITES. EXCRETION IN URINE AND FECES MEASURED DURING THE FIRST 3 WEEKS ACCORDED CLOSELY WITH THE PATTERNS DEDUCED BY DURBIN FROM THE REPORT OF LANGHAM ET AL. ON PATIENTS INJECTED WITH 239PU. HOWEVER, CONCENTRATIONS IN BLOOD WERE ROUGHLY TWICE THOSE SUGGESTED BY DURBIN DURING MOST OF THE 14 DAYS COVERED BY MEASUREMENTS. IN ONE SUBJECT, ROUGHLY 55 PERCENT OF THE INJECTION; IN THE OTHER, THE INCREASE WAS PROLONGED, REACHING 70 PERCENT AFTER SEVERAL MONTHS.