Document Details

Health Division and Biological Section of Research Division Report for the Month of May 1946
Subject Terms:
ORNL, pile, radiation, report; Victoreen pocket chamber; health division, medical; health physics, biology
Document Location:
DOE INFORMATION CENTER 1 Way, Oak Ridge, TN 37831; Eva Butler; Phone: 865-241-4780; Toll-Free: 800-382-6938, Option 6; FAX: 865-574-3521; Email:
Document Categories:
Health, Safety and Environment\Worker Health and Safety
Document Type:
Publication Date:
1946 May 31
Declassification Date:
1953 May 29
Declassification Status:
Document Pages:
Accession Number:
Document Number(s):
MonH-114, Copy 23A
Originating Research Org.:
Clinton Laboratories
OpenNet Entry Date:
1998 Jun 16
This document concerns the report for the month of May 1946. Pre-employment and termination examinations have continued at a slightly accelerated rate. New forms are being devised so that within the near future a complete set of workable forms will be available in order to accomplish accurate statistical records, accurate supply records, work simplification and more efficient routing of patients, and a better conception of the medical care required by the Clinton Laboratories' personnel. An operating manual for the Medical Section is being prepared, and plans have been developed for moderate revision of the facilities of the Medical Section. The graphite stringer Number 21 became jammed in the pile on April 30, 1946. A spill of monopotassium phosphate occurred during the manipulation of the stringer due to a broken sample can. Air activity in the Pile Building became excessive several times during the month, and most of the air contamination was traced to the exhaust from the pneumatic tube. During the transfer of metal waste solution from Tank A-6 to W-9 on May 9, 1946, a leaking valve contaminated the ground in the vicinity, and the area was roped off and contaminated dirt was removed to the burial ground. Recent summaries of information obtained with CF-1, ABC, A, and C-58 mice given small daily doses of fast neutrons or gamma rays, have revealed (1) the late effects consisted of generalized atrophy and neoplasia of hemopoietic organs attended by shortened life span, loss of weight, possible increased tumor incidence in organs other than hemopoietic, modified blood picture, and a changed pathology and histology; (2) generalized atrophy appeared to result from the inroads of subliminal damage which in time added up to the exhaustion of vital reserves; (3) different thresholds of damage were found; (4) threshold responses of the peripheral blood were at least a factor of 10 less sensitive than survival responses in CF-1 mice; (5) some differences were noted in the responses of different strains of animals, but these were more a matter of degree than of type and usually could be associated directly with species characteristics; (6) no fundamental differences were observed in the responses of males and females to radiation, although the effects being studied were sometimes obscured by sex features such as pugnaciousness in CF-1 males; (7) the r/n ratio of gamma rays to fast neutrons for the different effects varied roughly from 8 to 1 to 2 or 3 times this amount for the conditions and methods used; (8) evidence indicates the degree of biologic effect varies with dose and density of the ionization produced.

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