Document Details
Title:
CONSIDERATIONS IN THE ASSESSMENT OF PLUTONIUM DEPOSITION IN MAN
Author(s):
VOELZ, G [LOS ALAMOS SCIENTIFIC LABORATORY]; UMBARGER, J [LOS ALAMOS SCIENTIFIC LABORATORY]; MCINROY, J [LOS ALAMOS SCIENTIFIC LABORATORY]; HEALY, J [LOS ALAMOS SCIENTIFIC LABORATORY]
Subject Terms:
BODY BURDEN; MEASURING INSTRUMENTS; LYMPH NODES; PLUTONIUM 239; PROCEDURES; URINE; RADIATION DOSES; GRAPHS; PLUTONIUM DIOXIDE; EXCRETION; DATA; RADIONUCLIDE KINETICS; LUNGS; PLUTONIUM 238
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
REPORT
Publication Date:
1975 Dec 12
Declassification Status:
Never classified
Document Pages:
0021
Accession Number:
NV0067584
Document Number(s):
LAUR751887
Originating Research Org.:
LOS ALAMOS SCIENTIFIC LABORATORY
OpenNet Entry Date:
1994 Aug 26
OpenNet Modified Date:
2003 Sep 18
Description/Abstract:
DATA FROM HUMAN CASES OF PLUTONIUM INHALATION ARE USED TO ILLUSTRATE S EVERAL IMPORTANT PROBLEMS IN THE CURRENT METHODS OF ESTIMATING PLUTONI UM BODY BURDENS. INDIVIDUALS EXPOSED TO PLUTONIUM 238 OXIDE PARTICLES IN A HIGHLY INSOLUABLE MATRIX SHOWED AN UNUSUALLY SLOW RISING URINARY EXCRETION CURVE OVER 300-400 DAYS. IN VIVO CHEST COUNTS DURING THE FIR ST MONTHS ESTIMATED LUNG BURDENS TO BE 10-30 NANOCURIES BUT URINARY EX CRETION METHODS CALCULATE CRETION METHODS CALCULATE RESIDUAL SYSTEMIC BODY BURDENS OF 50 TO 100 NANOCURIES AT 1200 DAYS AFTER EXPOSURE. CURRENT ASSUMPTIONS USED IN TH E IN VIVO CALIBRATION DO NOT CONSIDER POSSIBLE LUNG DISTRIBUTION OF PA CRETION METHODS CALCULATE RESIDUAL SYSTEMIC BODY BURDENS OF 50 TO 100 NANOCURIES AT 1200 DAYS AFTER EXPOSURE. CURRENT ASSUMPTIONS USED IN TH E IN VIVO CALIBRATION DO NOT CONSIDER POSSIBLE LUNG DISTRIBUTION OF PA RTICULATES SOON AFTER EXPOSURE THAT COULD ALTER THE INTERPRETATION SIG NIFICANTLY.