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EPIDEMIOLOGICAL FOLLOW-UP OF THE NEW JERSEY RADIUM CASES I. REPORT OF THE MEDICAL STUDY GROUP II. RESUMES OF FINDINGS FROM ( TC )

FLORIN, A A; FISHER, H W; HENLE, C B; ET AL

Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV

REPORT

1964 Nov 30

Never classified

0049

NV0015190

NYO21812

NEW JERSEY DEPARTMENT OF HEALTH

1994 Aug 26

2003 Sep 18

EPIDEMIOLOGICAL FOLLOW-UP OF THE NEW JERSEY RADIUM CASES I. REPORT OF THE MEDICAL STUDY GROUP ( APRIL 1964 ) II. RESUMES OF FINDINGS FROM IN DIVIDUAL CASE STUDIES. SELECTED PRELIMINARY DATA RADIUM CASES STUDIED , AS WELL AS DATA ON CASES SEEN AT FOLLOW-UP EXAMINATIONS BY THE PROJE CT MEDICAL STAFF SINCE THE LAST PROGRESS REPORT (NYO-10604) ARE PRESEN TED. TEN ADDITIONAL RESUMES OF FINDINGS FROM INDIVIDUAL CASE STUDIES A RE INCLUDED, BRINGING THE TOTAL OF SUCH PUBLISHED RESUMES TO 160. FIVE PREVIOUSLY UNREPORTED MALIGANCIES WHICH HAVE BEEN ENCOUNTERED ARE LIST ED. FIVE RADIUM CASES DIED AND THREE POST MORTEM EXAMINATIONS WERE PER FORMED. DIAGNOSES FROM DEATH CERTIFICATES OR POST MORTEM EXAMINATIONS ARE PRESENTED. DEATH CERTIFICATES HAVE BEEN STUDIED FOR 212 PERSON KNO WN OR BELIEVED TO HAVE BEEN RADIUM WORKERS. A TOTAL OF 70 CASES AMONG THE 212 HAD MALIGANCIES MENTIONED ON THEIR DEATH CERTIFICATES. ELEVEN INDIVIDUALS SHOWED CHANGES ON ROENTGENOGRAMS IN THE INTERVAL BETWEEN I NITIAL AND FOLLOW-UP EXAMINATIONS. A SINGLE CASE HAS DEVELOPED MULTIPL E MYELOMA SINCE THE INITIAL EXAMINATION. BONE SPECIMENS FROM 15 CASES HAVE BEEN STUDIED ROENTGENOGRAPHICALLY TO DATE. PRELIMINARY COMPARISON S OF ROENTGENOGRAPHIC AND GROSS AND HISTOLOGY EXAMINATIONS OF BONE SPE CIMENS ARE PRESENTED. RESULTS OF SCORING ROENTGENOGRAPHS BY THE MIT AN D ARGONNE NATIONAL LABORATORY SYSTEM, AND BY A PROPOSED NEW JERSEY RAD IUM RESEARCH PROJECT SYSTEM, ARE PRESENTED, IN ADDITION TO A DETAILED CRITIQUE OF THE PROBLEMS INCLUDED IN DEVISING A SUTABLE SCORING SYSTEM . OSTEOSARCOMA, NECROSIS OF ARTICULAR ASPECT OF BONE, AND THE PRESENCE OF NUMEROUR PUNCHED-OUT RADIOLUCENCIES IN BONE APPEAR ON PRELIMINARY E XAMINATION TO BE ASSOCIATED IN THE REPORTED CASES WITH BODY BURDENS OF IN THE REPORTED CASES WITH BODY BURDENS OF RADIUM-226 IN EXCESS OF 0.0 247 MICROCURIE. FEW CASES UNUSUAL DENTAL CHANGES BETWEEN INITIAL AND F OLLOW-UP EXAMINATIONS. ALVEOLAR BONE HEALED SATISFACTORILY AFTER DENTA L PROCEDURES, IRRESPECTIVE OF BODY BURDEN. PATHOLOGY STUDIES WHICH HAV E BEEN PERFORMED ON CASE SPECIMENS ARE REPORTED.