Document Details


Title:
COMPARATIVE UTILIZATION OF DIETARY RADIUM-226 AND OTHER ALKALINE EARTHS BY PIGS AND SHEEP ( IN 8397 ) ( RA-226)
Subject Terms:
MEETINGS; BARIUM; MAGNESIUM; RADIUM; STRONTIUM; SHEEP; SWINE; DIET; CALCIUM; METABOLISM; INGESTION; RADIONUCLIDE KINETICS
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
JOURNAL ARTICLE
Publication Date:
1969 May 05
Declassification Status:
Never classified
Document Pages:
0008
Accession Number:
NV0008625
Originating Research Org.:
HEALTH AND SAFETY LABORATORY - ATOMIC ENERGY COMMI
OpenNet Entry Date:
1994 Aug 26
OpenNet Modified Date:
2003 Sep 18
Description/Abstract:
SKELETAL AND SOFT-TISSUE BURDENS OF THE ALKALINE-EARTH ELEMENTS (MG, S R, BA, AND 226-RA), INCLUDING 90-SR, WERE MEASURED IN PIGS AND SHEEP A T VARIOUS STAGES OF GROWTH. INTAKES OF THESE SAME NUCLIDES BY THE PIG S FROM BIRTH TO 177 DAYS AND BY THE SHEEP FROM ABOUT 155 TO 285 DAYS W ERE ALSO MEASURED. THE PIGS RECEIVED ONLY MILK DURING THE FIRST 6 WEE KS, AFTER WHICH THEY WERE FED THE SAME DRY FEED AND DEIONIZED WATER AS WERE THE SHEEP DURING THE CONTROLLED PERIOD. MARKED SPECIES DIFFEREN CES WERE OBSERVED IN THE EXTENT TO WHICH THE PIGS AND SHEEP UTILIZED T HE ALKALINE EARTHS FROM THEIR DIET. FROM BIRTH TO MATURITY, THE PIGS USED THE FOLLOWING PERCENTAGES OF THEIR DIETARY ALLOWANCES: 47 CA, 6.5 SR, 1.0 BA, AND 0.5 RA; THE SHEEP DURING THE CONTROLLED PERIOD USED 17 CA, 7.8 SR, 11.0 BA, AND 9.2 RA. LESS THAN HALF OF THE PI G RADIUM BURDEN AT 117 DAYS WAS IN THE SKELETON, AND 97 OF THE SHEEP RADIUM BURDEN WAS CONFINED TO THE SKELETON. ESSENTIALLY ALL THE 226-R A IN THE MILK CONSUMED BY THE PIG WAS UTILIZED. ALTHOUGH HUMANS AND L OWER ANIMALS ABSORB AND RETAIN CALCIUM IN PREFERENCE TO STRONTIUM, THE PHYSIOLOGICAL FACTORS INVOLVED IN THIS DISCRIMINATION BETWEEN TWO CHE MICALLY SIMILAR ELEMENTS ARE NOT WELL UNDERSTOOD. BY STUDYING THE COM PARATIVE UPTAKE AND RETENTION OF THE ALKALINE-EARTH ELEMENTS IN A RUMI NANT AND NONRUMINANT ANIMAL, WE HAVE GAINED INFORMATION THAT MAY FURTH ER OUR UNDERSTANDING OF COMPARATIVE ALKALINE-EARTH METABOLISM IN MAN.


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