Document Details


Title:
OPERATION UPSHOT-KNOTHOLE, NEVADA PROVING GROUNDS, MARCH - JUNE 1953, PROJECT 23.2, BACTERIOLOGICAL STUDIES ON ANIMALS EXPOSED TO NEUTRON RADIATION
Subject Terms:
BACTERIA; BIOLOGICAL EFFECTS; FALLOUT; ANIMALS; NEUTRONS; RADIATION DOSES; RADIATION INJURIES; UPSHOT OPERATION; UPSHOT-KNOTHOLE OPERATION
Document Location:
Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV
Document Type:
REPORT
Publication Date:
1953 Jul 31
Declassification Status:
Unknown
Document Pages:
0022
Accession Number:
NV0006189
Document Number(s):
WT794
Originating Research Org.:
UNITED STATES NAVAL RADIOLOGICAL DEFENSE LABORATOR
OpenNet Entry Date:
1994 Aug 26
OpenNet Modified Date:
2003 Sep 18
Description/Abstract:
MICE EXPOSED TO SUPRALETNAL DOSES OF NEUTRON RADIATION AND COMBINED NE UTRON AND GAMMA RADIATION FROM THE NUCLEAR DEVICE USED IN UPSHOT-KNOTH OLE 9 (MAY 8, 1953) DIED WITHIN 2 1/2 TO 4 DAYS. BACTERIOLOGICAL EXAM INATION OF THE HEART BLOOD AND SPLEEN FROM ANIMALS SACRIFICED WHILE MO RIBUND REVEALED THAT 78 PER CENT OF THE ANIMALS RECEIVING ONLY NEUTRON RADIATION AND 96 PER CENT OF THE ANIMALS RECEIVING COMBINED NEUTRON A ND GAMMA RADIATION SUFFERED AN EXTENSIVE INVASION BY THE NORMAL INTEST INAL BACTERIA. CONTRARY TO FINDINGS REPORTED ELSEWHERE ON ANIMALS EXP OSED TO X RAYS, INVASION BY TWO OR MORE SPECIES OF BACTERIA WAS FOUND TO BE A COMMON OCCURRENCE. IN A LARGE NUMBER OF ANIMALS EXAMINED, POS ITIVE CULTURES WERE OBTAINED ONLY FROM THE SPLEEN. THIS IS INTERPRETE D AS INDICATING THAT, ALTHOUGH THE FILTERING MECHANISM OF THE SPLEEN S TILL FUNCTIONED, THIS ORGAN WAS UNABLE TO DESTROY THE INVADING BACTERI A EITHER BECAUSE OF THE OVERWHELMING NUMBER OF BACTERIA OR BECAUSE OF THE INJURY TO THE SPLEEN ITSELF. HENCE, THE ORGANISMS CONTINUED TO MU LTIPLY AND EVENTUALLY SPILLED BACK INTO THE CIRCULATORY SYSTEM.


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