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TREATMENT OF ACUTE RADIATION INJURY UNDER MEDICALLY AUSTERE CONDITIONS

WALD, N; HINSHAW, J R; AMES, W R; INGRAM, M; THOMAS, E D; UNRUH, C M; ANDREWS, G A; BRENNAN, J T; SAENGER, E L; ANDERSON, C G; HEKHUIS, G L; BOND, V P

TBI/PBI

Location - DOE/NNSA NUCLEAR TESTING ARCHIVE Address - P.O. Box 98521 City - Las Vegas State - NV Zip - 89193-8521 Phone - (702)794-5106 Fax - (702)862-4240 Email - NTA@NV.DOE.GOV

REPORT

1967 Apr 01

Unknown

0058

NV0757922

TRC-67-21

DEFENSE NUCLEAR AGENCY, U.S.

1999 Jul 13

2003 Sep 18

THIS REPORT SUMMARIZES THE WORK OF A COMMITTEE CONVENED TO DEFINE THE BEST PLAN FOR MEDICAL MANAGEMENT OF LARGE NUMBERS OF RADIATION CASUALTIES UNDER AUSTERE MEDICAL CONDITIONS AND TO EVALUATE SPECIFIC COURSES OF RESEARCH WHICH WOULD IMPROVE THE ABILITY TO COPE WITH CIVIL DEFENSE ASPECTS OF RADIATION SICKNESS. RADIATION INJURY IS VIEWED AS ONLY ONE OF A NUMBER OF NOXIOUS AGENTS WHICH MIGHT BE EXPECTED TO ACT CUMULATIVELY OR SYNERGISTICALLY UNDER THE SHELTER CONDITIONS POSTULATED. THE MEDICAL SIGNIFICANCE OF PRE-EXISTING DISEASE AND DISABILITY IN THE SHELTER POPULATION AND THE MEDICAL EFFECTS OF CONFINE LARGE RANDOMLY SELECTED GROUPS OF PERSONS UNDER THE AUSTERE CONDITIONS POSTULATED ARE EMPHASIZED THROUGHOUT. MEASURES MOST LIKELY TO INFLUENCE ULTIMATE RADIATION-RELATED MORTALITY INCLUDE MANAGEMENT OF INFECTION AND OF HEMORRHAGIC MANIFESTATIONS OF RADIATION INJURY, AND MANAGEMENT OF SURGICAL PROBLEMS. AVAILABLE CHEMICAL "PROTECTIVE AGENTS" ARE MENTIONED BUT THEIR EFFECTIVENESS IN PREVENTING RADIATION MORTALITY IS CONSIDERED TO BE DOUBTFUL UNDER SHELTER CONDITIONS POSTULATED. SPACE AND WATER ARE THE MOST IMPORTANT REQUIREMENTS FOR SURVIVAL UNDER SHELTER CONDITIONS, AND PRESENT ALLOCATIONS SHOULD BE REVISED. RECOMMENDATIONS FOR SPECIFIC RESEARCH ARE MADE BUT THESE RECOMMENDATIONS WOULD BE SUBJECT TO REVISION, DEPENDING UPON THE OUTCOME OF THE RECOMMENDATIONS WITH RESPECT TO OPERATIONS.