National Library of Energy BETA

Sample records for rch aberd een

  1. Basic ReseaRch DiRections

    National Nuclear Security Administration (NNSA)

    Basic ReseaRch DiRections for User Science at the National Ignition Facility Report on the National Nuclear Security Administration - Office of Science Workshop on Basic Research Directions on User Science at the National Ignition Facility BASIC RESEARCH DIRECTIONS FOR USER SCIENCE AT THE NATIONAL IGNITION FACILITY Report on the National Nuclear Security Administration (NNSA) - Office of Science (SC) Workshop on Basic Research Directions on User Science at the National Ignition Facility Chairs:

  2. EEN Hellas | Open Energy Information

    OpenEI (Open Energy Information) [EERE & EIA]

    Place: Greece Product: EEN Hellas subsidiary of EDF Energies Nouvelles. It develops, finances and operates energy projects in Greece. References: EEN Hellas1 This article is a...

  3. Pontotoc Co. Greene Co. Hale Co. OAK GROVE C OAL D EGAS CEDAR...

    Gasoline and Diesel Fuel Update

    LITT LE SAND Y CREEK COAL D EGAS FAYETTE SW FAYETTE N WAT TS CR EEKALD YELLOW CR EEKALD RPDOKTIBBEHACNT Y-1 BALLS BRAN CH BU TT AH ATCH IE RIVER NETT LET ON ABERD EEN E ...

  4. OAK GROVE C OAL D EGAS CEDAR COVE COAL D EGAS BLU E CREEK COAL...

    Gasoline and Diesel Fuel Update

    LITT LE SAND Y CREEK COAL D EGAS FAYETTE SW FAYETTE N WAT TS CR EEKALD YELLOW CR EEKALD RPDOKTIBBEHACNT Y-1 BALLS BRAN CH BU TT AH ATCH IE RIVER NETT LET ON ABERD EEN E ...

  5. Pontotoc Co. Greene Co. Hale Co. OAK GROVE C OAL D EGAS CEDAR...

    Annual Energy Outlook

    LITT LE SAND Y CREEK COAL DEGAS FAYETTE SW FAYETTE N WAT TS CR EEKALD YELLOW CR EEKALD RPDOKTIBBEHACNT Y-1 BALLS BRAN CH BU TT AH ATCH IE RIVER NETT LETON ABERD EEN E TAYLOR ...

  6. EEN regulates the proliferation and survival of multiple myeloma cells by potentiating IGF-1 secretion

    SciTech Connect

    Huang, Er-Wen; Xue, Sheng-Jiang; Li, Xiao-Yan; Xu, Suo-Wen; Cheng, Jian-Ding; Zheng, Jin-Xiang; Shi, He; Lv, Guo-Li; Li, Zhi-Gang; Li, Yue; Liu, Chang-Hui; Chen, Xiao-Hui; Liu, Hong; Li, Jie; Liu, Chao

    2014-05-02

    Highlights: • Levels of EEN expression paralleled with the rate of cell proliferation. • EEN was involved in the proliferation and survival of multiple myeloma (MM) cells. • EEN regulated the activity of IGF-1-Akt/mTOR pathway. • EEN regulated proliferation and survival of MM cells by enhancing IGF-1 secretion. - Abstract: The molecular mechanisms of multiple myeloma are not well defined. EEN is an endocytosis-regulating molecule. Here we report that EEN regulates the proliferation and survival of multiple myeloma cells, by regulating IGF-1 secretion. In the present study, we observed that EEN expression paralleled with cell proliferation, EEN accelerated cell proliferation, facilitated cell cycle transition from G1 to S phase by regulating cyclin-dependent kinases (CDKs) pathway, and delayed cell apoptosis via Bcl2/Bax-mitochondrial pathway. Mechanistically, we found that EEN was indispensable for insulin-like growth factor-1 (IGF-1) secretion and the activation of protein kinase B-mammalian target of rapamycin (Akt-mTOR) pathway. Exogenous IGF-1 overcame the phenotype of EEN depletion, while IGF-1 neutralization overcame that of EEN over-expression. Collectively, these data suggest that EEN may play a pivotal role in excessive cell proliferation and insufficient cell apoptosis of bone marrow plasma cells in multiple myeloma. Therefore, EEN may represent a potential diagnostic marker or therapeutic target for multiple myeloma.

  7. Basic ReseaRch DiRections

    National Nuclear Security Administration (NNSA)

    Report on the National Nuclear Security Administration - Office of Science Workshop on ... IGNITION FACILITY Report on the National Nuclear Security Administration (NNSA) - Office ...

  8. MEMORANDUM TO: F I L E S I T E NAME: ALTERNATE

    Office of Legacy Management (LM)

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  9. I

    Office of Legacy Management (LM)

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  10. NMMSS Newsletter, March 2009

    National Nuclear Security Administration (NNSA)

    R e p o rtin g M o n th T ra n s a c tio ns D u e In ve n to ry D u e Ja n ua ry 2 0 0 9 F e b ru a ry 1 0 F e b ru a ry 1 6 F e b ru a ry 2 0 09 M a rch 1 1 M a rch 1 6 M a rch 2 00 9 A p ril 1 0 A p ril 1 5 A p ril 2 0 09 M a y 1 2 M a y 1 5 M a y 2 0 0 9 Ju n e 1 0 Ju n e 1 5

  11. Synthesis and characterization of molybdenum complexes containing diphosphine ligands of the type (ArCH{sub 2}){sub 2}PC{sub 2}H{sub 4}P(CH{sub 2}Ar){sub 2} (Ar = C{sub 6}H{sub 4}X). Electronic control of {eta}{sup 2}-dihydrogen versus dihydride coordination in MoH{sub 2}(CO)((RCH{sub 2}){sub 2}PC{sub 2}H{sub 4}P(CH{sub 2}R){sub 2}){sub 2} (R = Me, Pr{sup i}, C{sub 6}H{sub 4}X) and implications on the reaction coordinate for H{sub 2} cleavage

    SciTech Connect

    Luo, Xiao-Liang; Kubas, G.J.; Burns, C.J.; Eckert, J.

    1994-11-09

    The bis(dinitrogen) molybdenum complexes trans-Mo(N{sub 2}){sub 2}((ArCH{sub 2}){sub 2}PC{sub 2}H{sub 4}P(CH{sub 2}Ar){sub 2}){sub 2} (Ar = C{sub 6}H{sub 5} (1a), C{sub 6}H{sub 4-} m-Me (1b), C{sub 6}H{sub 4}-o-Me (1c), C{sub 6}H{sub 4}-p-Me (1d), C{sub 6}H{sub 4}-o-F (1e), C{sub 6}H{sub 4}-m-F (1f) C{sub 6}H{sub 4}-p-F (1g), C{sub 6}H{sub 4}-m-OMe (1h), C{sub 6}H{sub 4}-p-OMe (1i)) are prepared by reduction of MoCl{sub 5} with magnesium under a dinitrogen atmosphere in the presence of the appropriate diphosphine ligand. Treatment of 1a and 1b with ethyl acetate in refluxing benzene under argon affords the formally 16-electron complexes MoCl{sub 5} with magnesium under a dinitrogen atmosphere in the presence of the appropriate diphosphine ligand. Treatment of 1a and 1b with ethyl acetate in refluxing benzene under argon affords the formally 16-electron complexes Mo(CO)((ArCH{sub 2}){sub 2}PC{sub 2}H{sub 4}P(CH{sub 2}Ar){sub 2}){sub 2} (Ar = C{sub 6}H{sub 5} (2a), C{sub 6}H{sub 4}-m-Me (2b)), which are shown by {sup 1}H NMR spectroscopy to contain an agostic Mo{hor_ellipsis}H-C interaction between the molybdenum and an ortho aryl hydrogen atom. The {eta}{sup 2}-H{sub 2} coordination in 3a and 3b is unambiguously established by IR, NMR, and neutron scattering spectroscopies and a single-crystal X-ray diffraction analysis of 3b. The predisposition toward hydrogen dissociation in these complexes is discussed.

  12. Nanogeochemistry: Geochemical reactions and mass transfers in...

    Office of Scientific and Technical Information (OSTI)

    ...een-Prokaryotic-and-Eukaryotic-Cellsslide2150310 Sandia National Laboratories ... (80 m2g) in fault gouge accounting for >50% energy consumed in earthquake http:...

  13. Nitroaliphatic difluoroformals

    DOEpatents

    Peters, Howard M.; Simon, Jr., Robert L.

    1978-01-01

    Nitroaliphatic difluoroformals of the formula RCH.sub.2 OCF.sub.2 OCH.sub.2 R' wherein R = FC(NO.sub.2).sub.2 -- and R' = F.sub.2 C(NO.sub.2)-- or CF.sub.3 --; or R = R' = CF.sub.3 OCH.sub.2 C(NO.sub.2).sub.2 --. The compounds are prepared in accordance with the following reaction: ##STR1## carried out at temperatures of from about 95.degree. C to about 150.degree. C. The compounds are especially useful as energetic plasticizers in explosive compositions.

  14. Microsoft Word - November2015draft.docx

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    On t he L ab's p roperty, nine s ites have b een identified for inclusion within the Park. Gun S ite F acilities: TA--- 8 --- 1 Laboratory a nd S hop, TA--- 8 --- 2 S hop a nd ...

  15. Jay Srinivasan! Group Lead, Computational Systems!

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Group Lead, Computational Systems! NUG - Feb 2015 Computational Systems Update NERSC - 2014 --- 2 --- Sponsored C ompute S ystems Carver, P DSF, J GI, K BASE, H EP 8 x F DR I B /global/ scratch 4 PB /project 5 PB /home 250 TB 45 P B s tored, 2 40 P B capacity, 4 0 y ears o f community d ata HPSS 48 GB/s 2.2 P B L ocal Scratch 70 GB/s 6.4 P B L ocal Scratch 140 GB/s 80 GB/s 2 x 10 Gb 1 x 100 Gb Science D ata N etwork Vis & A naly?cs, D ata T ransfer N odes, Adv. A rch., S cience G ateways 80

  16. WIPP Update 5_15_14

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    WIPP e vent b ioassay t esting program c omes t o a c lose Final b ioassay r esults f rom t he F ebruary 1 4 r adiological e vent h ave b een r eported. T he m aximum lifetime...

  17. Geophex Airborne Unmanned Survey System

    SciTech Connect

    Won, I.L.; Keiswetter, D.

    1995-12-31

    Ground-based surveys place personnel at risk due to the proximity of buried unexploded ordnance (UXO) items or by exposure to radioactive materials and hazardous chemicals. The purpose of this effort is to design, construct, and evaluate a portable, remotely-piloted, airborne, geophysical survey system. This non-intrusive system will provide stand-off capability to conduct surveys and detect buried objects, structures, and conditions of interest at hazardous locations. During a survey, the operators remain remote from, but within visual distance of, the site. The sensor system never contacts the Earth, but can be positioned near the ground so that weak geophysical anomalies can be detected. The Geophex Airborne Unmanned Survey System (GAUSS) is designed to detect and locate small-scale anomalies at hazardous sites using magnetic and electromagnetic survey techniques. The system consists of a remotely-piloted, radio-controlled, model helicopter (RCH) with flight computer, light-weight geophysical sensors, an electronic positioning system, a data telemetry system, and a computer base-station. The report describes GAUSS and its test results.

  18. Gainache. Lori M From: Conrad, Jill A

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Gainache. Lori M From: Conrad, Jill A Setit:Friday, February 15, 2013 LOS PM TO: Alex Nazara-i Lale)(nazarali@ctuir~org), Alyssa Buck (Abuc k1gcrpLjd.Org), HNRTC Smith, Anthory; 'Rambi Rodriquez (ba mbirod riquez@ctu i .rg.)Y; 'Barbara Harper (barbaraharer@ctuir.com)'; HNRTC - Landeen, Dan, Dana Mil ler (drn1er@yrenr.com). Darla lackson (darlaijnezperce-org); Dave Rowland (b)(6) davidb@nezperce.org; Doreen Dogsleep {ddoogs een@ynerwm ~corn); HNRTC - Bohnee, Gabriel; 'George Klin~ger (gedrgek

  19. Catalytic Combustion for Ultra-Low NOx Hydrogen Turbines

    SciTech Connect

    Etemad, Shahrokh; Baird, Benjamin; Alavandi, Sandeep

    2011-06-30

    Precision Combustion, Inc., (PCI) in close collaboration with Solar Turbines, Incorporated, has developed and demonstrated a combustion system for hydrogen fueled turbines that reduces NOx to low single digit level while maintaining or improving current levels of efficiency and eliminating emissions of carbon dioxide. Full scale Rich Catalytic Hydrogen (RCH1) injector was developed and successfully tested at Solar Turbines, Incorporated high pressure test facility demonstrating low single digit NOx emissions for hydrogen fuel in the range of 2200F-2750F. This development work was based on initial subscale development for faster turnaround and reduced cost. Subscale testing provided promising results for 42% and 52% H2 with NOx emissions of less than 2 ppm with improved flame stability. In addition, catalytic reactor element testing for substrate oxidation, thermal cyclic injector testing to simulate start-stop operation in a gas turbine environment, and steady state 15 atm. operation testing were performed successfully. The testing demonstrated stable and robust catalytic element component life for gas turbine conditions. The benefit of the catalytic hydrogen combustor technology includes capability of delivering near-zero NOx without costly post-combustion controls and without requirement for added sulfur control. In addition, reduced acoustics increase gas turbine component life. These advantages advances Department of Energy (DOE’s) objectives for achievement of low single digit NOx emissions, improvement in efficiency vs. postcombustion controls, fuel flexibility, a significant net reduction in Integrated Gasification Combined Cycle (IGCC) system net capital and operating costs, and a route to commercialization across the power generation field from micro turbines to industrial and utility turbines.

  20. APS2013_Koniges.pptx

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Number o f C ores Speedup The P IC c ode W arp s cales w ell o n H opper a nd E dison with E dison b eing ~ 2X f aster t han H opper Warp h as b een s hown t o scale t o 1 28k o n H opper Plasma P hysics S imulaAons o n N ext G eneraAon P laEorms A. K oniges, R . G erber, D . S kinner, Y . Y ao, Y . H e, D . G rote, J ---L V ay, H . K aiser, a nd T . S terling APS D ivision o f P lasma P hysics A nnual M eeOng, D enver, C O, N ovember 2 013 --- M ore t han 5 00 c ores --- O pAmized f or S IMD (

  1. Microsoft Word - WIPP Update 12.9.14.doc

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    December 9 , 2 014 WIPP e mployees e ncounter o dor w hile m onitoring w aste c ontainers Late l ast w eek, f our w aste h andling t echnicians a t t he W aste I solation P ilot P lant ( WIPP) w ere p erforming s urface temperature m easurements o n t ransuranic w aste c ontainers i n t he W aste H andling B ay w hen t hey e ncountered an a bnormal o dor. T he o dor w as d escribed a s a " cleaning s olution---like" o dor, s imilar t o o dors t hat h ave b een detected i n t he p ast w

  2. Microsoft Word - Document11

    U.S. Department of Energy (DOE) - all webpages (Extended Search)

    Margaret L ivingstone What A rt C an T ell Us A bout T he Brain Abstract: Artists h ave b een d oing e xperiments o n v ision l onger t han n eurobiologists. S ome major w orks o f a rt h ave p rovided i nsights a s t o h ow w e s ee; s ome o f t hese i nsights are s o f undamental t hat t hey c an b e u nderstood i n t erms o f t he u nderlying neurobiology. F or e xample, a rtists h ave l ong r ealized t hat c olor a nd l uminance c an play i ndependent r oles i n v isual p erception. P icasso